Investigating biomolecules at near-atomic resolutions allows you to explore the very architecture of life. Cryo electron microscopy (Cryo-EM) single particle analysis is rapidly becoming a mainstream structural biology technique, facilitating the study of:
- Dynamic biological processes
- Protein structure
- Protein complexes and aggregates
- Large virus assemblies
Cryo-electron microscopy is a multi-step process. See how it can speed up your research and development with our single particle analysis workflow:
Multi-level support at every stage
You can rely on our expertise to support both your investment and your research endeavors. Our highly knowledgeable cryo-EM application specialists can assist with everything from sample preparation to data processing. Rest assured when you trust your long-term ongoing support to a cryo-EM leader currently supporting 100+ systems worldwide.
Advice for planning and building
Control costs and limit laboratory downtime by relying on our advanced expertise of lab infrastructure. Thermo Fisher Scientific offers the expertise you need to precisely plan every aspect of your laboratory, helping to reduce building costs, while optimizing your laboratory for the best results.
Flexible options to get you in the game
We provide a variety of ways to meet your financial needs, from assistance with grants to leasing and financing options. Our experts are well versed in the unique procurement requirements of universities, governments, industry and research labs.
Structure-guided design of SARS-CoV-2 antivirals
Register to watch our recorded webinar from Dr. Quan Wang of ShanghaiTech University and Dr. Renhong Yan of Westlake University on new cryo-EM studies of the structural basis of key molecular processes including RNA replication/transcription and receptor recognition.
Determining protein and small molecule structures with Microcrystal Electron Diffraction.
Structure-guided design of SARS-CoV-2 antivirals
Register to watch our recorded webinar from Dr. Quan Wang of ShanghaiTech University and Dr. Renhong Yan of Westlake University on new cryo-EM studies of the structural basis of key molecular processes including RNA replication/transcription and receptor recognition.
Determining protein and small molecule structures with Microcrystal Electron Diffraction.
Structural Biology Research
Cryo-electron microscopy enables the structural analysis of challenging biological targets such as large complexes, flexible species and membrane protein.
Infectious Disease Research
Cryo-EM techniques enable multiscale observations of 3D biological structures in their near-native states, informing faster, more efficient development of therapeutics.
Drug Discovery
Learn how to take advantage of rational drug design for many more major drug target classes, leading to best-in-class drugs.
Cryo-electron microscopy provides near-atomic resolution 3D protein structure. It can determine structural information for complexes and crystallization-resistant samples, as well as vital cellular context.
Cryo-EM enables the 3D structural visualization of virus particles, and the antigen-antibody interface, at near-atomic resolutions. A virus’s inherent structural symmetry makes it the ideal target for cryo-EM analysis.
