Life Science Imaging Techniques Supported by Amira Software

Cryo-TEM and cryo-electron tomography (cryo-ET) are cutting-edge cryogenic imaging techniques that provide high-resolution insights into cellular structures and protein complexes in their native states. Amira Software is a powerful, multifaceted platform designed for the visualization, manipulation, and analysis of 3D-image data for cryo-ET and cryo-TEM. It offers a comprehensive toolbox that includes AI-based image denoising, precise segmentation, and rapid filament analysis, enabling researchers to transform complex imaging data into insights. Amira Software leverages AI for semi-automated analysis of cryo-TEM images of viral particles and nanocarriers, significantly accelerating the drug development process while ensuring reliable and standardized analysis. With features like ergonomic manual annotation and cross-correlation-based cylindric template matching, Amira Software significantly reduces the time required for data analysis, making it an essential tool for cell biologists and pharmaceutical researchers aiming to understand cellular structures and functions at a deeper level.

Volume electron microscopy (volume EM) is a transformative imaging technique that enables researchers to visualize and analyze the intricate 3D ultrastructure of cells and tissues at nanometer resolution. Amira Software offers user-friendly and precise tools dedicated for volume EM data quality enhancement and analysis for all common modalities: array tomography, SBF-SEM, and FIB-SEM. Furthermore, the Thermo Scientific Volumescope 2 SEM and Amira Software offer a powerful combination for this approach. The fully integrated workflow from acquisition to image analysis seamlessly transforms images into quantitative information. Amira Live Tracker allows visualization and navigation of 3D images data during acquisition, optimizing imaging outcomes and automating 3D volume reconstructions. The imported 3D images can be further processed and analyzed within Amira Software using AI-based automated workflows.

Experience faster, more accurate insights with Amira Software, offering streamlined workflows, enhanced data analysis, and optimized research outcomes for your volume EM data.

Amira Software, with its robust architecture for multi-volume data processing and visualization, is a preferred tool for researchers integrating data from diverse imaging modalities. It offers seamless integration of structural and functional information across multiple scales, supported by flexible and precise automatic registration tools in the Multi-Planar Workroom. This enables researchers to conduct correlative studies using proven intermodal registration methods, enhancing workflows across numerous fields in the life sciences.

Amira Software's advanced visualization capabilities enable the generation of detailed 3D reconstructions from 2D light microscopy images, offering deeper insights into the structure and function of biological specimens. The software includes sophisticated image processing techniques such as deconvolution, segmentation, and quantitative analysis, allowing researchers to extract meaningful information from their data.

Amira Software supports a wide range of file formats commonly used in light microscopy, ensuring seamless integration with various imaging systems.

Amira Software addresses MRI challenges such as complex data interpretation, high noise levels, and the need for precise anatomical differentiation with advanced imaging, detailed separation, and comprehensive examination tools. It facilitates the creation of intricate 3D reconstructions, allowing researchers to explore anatomical structures with precision. Amira Software supports quantitative analysis, including volumetric measurements and statistical evaluations, enhancing MRI dataset interpretation. Its user-friendly interface and customizable workflows streamline MRI data analysis, making it an ideal tool in both clinical and research settings.

Amira Software is an ideal choice for bioengineers and preclinical researchers, offering advanced tools for bone segmentation, separation, and detailed measurement in 3D models. Its robust, semi-automated workflows, including specialized cortical and trabecular bone segmentation, save time and effort. Amira Software's performance-optimized registration tools and multi-volume architecture enable automatic co-registration of image data, facilitating in vivo distribution studies of therapeutic agents tagged with radioactive nuclei. Its comprehensive toolbox allows for precise anatomical segmentation and quantification of radiotracer uptake in functional images.