Atomic resolution cryo-EM with enhanced productivity and compact design


The award-winning Thermo Scientific Krios G4 Cryo-Transmission Electron Microscope (Cryo-TEM) enables you to unravel life at the atomic level—easier, faster, and more reliably than ever before. The most compact TEM in its class, the Krios G4 Cryo-TEM consists of a highly stable 300 kV TEM platform and the industry-leading Autoloader (a cryogenic sample manipulation robot), making it ideally suited for automated applications such as cryo-electron tomography (cryo-ET), single-particle analysis (SPA), and micro-electron diffraction (MicroED).

Krios G4 Cryo-TEM features

Atomic resolution cryo-EM

Solve more structures at record-breaking resolutions with the Krios G4 Cryo-TEM. Increase your lab’s productivity and performance with innovative upgrades.

Innovative technology and software

The Thermo Scientific Selectris X Imaging Filter with Thermo Scientific Falcon 4i Direct Electron Detector and Thermo Scientific E-CFEG cold field emission source improve image contrast to reach higher resolutions in shorter time.

Every Krios Cryo-TEM has a story

To unlock the mysteries of life -- aging, curing disease, and enhancing health, scientists require deep understanding of cell behavior, functionality, and structure.

Krios Cryo-TEM resources

Learn more from scientists who are using the Krios Cryo-TEM in their research and take a closer look with on-demand webinars.

Cryo-TEM service and support

To ensure optimal system performance, we provide you access to a world-class network of field service experts, technical support, and workflow validation.

Cryo-EM in biosafety labs

Our decontamination solution enables pathogen research and comprehensive instrument service in higher biosafety-level containment facilities (e.g. BSL3).