Therapeutic drug monitoring (TDM) represents significant workflow demands and revenue generation for clinical laboratories. A high throughput, validated paper spray mass spectrometry assay using the Thermo Scientific VeriSpray source is presented as a facile and rapid TDM strategy for the direct, quantitative analysis of clozapine and its metabolite in human serum samples. Quantitative results obtained compare favourably with a validated clinical LC-MS assay.

For Research Use Only. Not for use in diagnostic procedures.

 

About the presenter

Chris Gill, Chemistry Professor, Vancouver Island University

Chris Gill, Chemistry Professor, Vancouver Island University

    Chris is a Chemistry Professor at Vancouver Island University (Nanaimo, BC) as well as co-director of the Applied Environmental Research Laboratories (AERL). He maintains an active international collaboration network, including the tenure of visiting professorships during sabbaticals in Germany and Italy. He has been awarded the Distinguished Researcher Award at VIU, a Distinguished Chemistry Alumni Award at the University of British Columbia, and has recently moved his laboratories into expanded space in the recently completed VIU Health and Sciences Centre.

 
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Resources

CMD Wide-format style fixes
Style Sheet for Global Design System