Practical paths to accessing cryo-EM
Thermo Fisher Scientific offers accessible ways to leverage the advantages of cryo-EM without making a full investment. Explore options for various levels of cryo-EM access and support and walk away with never-before-seen structures that prove the power of cryo-EM for your work.
Cryo-EM labs and service centers
Ideal for: Scientists in drug discovery who want secure, supported access to facilitate faster success.
What it is: Three levels of service to support every step as you apply cryo-EM to your projects.
Where: Service centers located around the world partner with Thermo Fisher Scientific.
Ideal for: Academic researchers who want to steer their facility selection and access state-of-the-art technology.
What it is: A laboratory directory that makes it easier to find a facility and jumpstart your next discovery.
Where: More than 15 centralized facilities located around the world.
Cryo-EM contract research organizations
Our partner service centers include contract research organizations (CRO) that offer three unique levels of cryo-EM service. These service options offer practical resources so you can get fast, reliable cryo-EM results tailored to the biopharmaceutical industry and build the confidence you need to start solving your structures. In this controlled environment, you can discover the value and true potential of cryo-EM for structure-based drug design. Learn the technology from cryo-EM experts and give yourself an unprecedented advantage with never-before-seen structural insights that make for more effective drugs. In using these services, you’ll also learn cryo-EM basics and theory through one-on-one sessions with experts at the service centers.
Three levels of service to accommodate your needs and support you every step of the way:
- Starter Kit (Level 1): Determine if cryo-EM is right for your sample
- Explore (Level 2): Obtain 3D structural insights for your project
- Impact (Level 3): Apply cryo-EM to multiple projects
State-of-the-art centralized facilities
Structural biologists increasingly turn to cryo-EM to understand challenging biological proteins that are hard to crystalize. Thermo Fisher Scientific connects you to world-class facilities where you can advance your research by obtaining cryo-EM structures and proof of concept data for cryo-EM using your own samples. Most facilities have an application form that will guide you through proposal requirements. Although the requirements vary by facility, generally you can expect to submit a research proposal for independent scientific and technical evaluation that speaks to the following:
- Scientific background and project significance
- Technical suitability and feasibility including descriptions of the sample and sample quality
Individual facilities also offer different levels of service, which may include sample preparation, grid screening, and cryo-EM training. Here you’ll find a list of global facilities. Select a region and click on the facility name to visit their website and learn more about next steps.
HHMI Janelia research Campus Cryo-EM facility | Ashburn, VA
Pacific Northwest Cryo-EM Center | Portland, OR
Princeton University Imaging & Analysis Center | Princeton, NJ
Purdue Cryo-EM Facility | West Lafayette, IN
Stanford-SLAC Cryo-EM Facilities | Menlo Park, CA
University of Massachusetts Medical School Cryo-EM Core Facility | Worcester, MA
Ceitec Cryo-Electron Microscopy and Tomography Core Facility | Brno, Czech Republic
Diamond Electron Bio-Imaging Centre (eBIC) | Oxfordshire, England
EMBL Cryo-Electron Microscopy Service Platform | Heidelberg, Germany
ESRF Cryo-EM Facility | Grenoble, France
NeCEN | Leiden, Netherlands
SciLifeLab Cryo-EM National Facility | Stockholm and Umeå, Sweden
National Centre for Biological Science Cryo-EM Facility | Bangalore, India
University of Wollongong Cryo-EM Facility | Wollongong, Australia