The screening and routine quantitation of veterinary drugs in diverse sample matrices are demanding applications that require laboratories to develop workflows that will not only address regulatory guidelines, but also enable detection of compounds beyond the scope of routine targeted quantitative assays.
This presentation will discuss two workflow solutions. First, we will present a new multi-class, multi-residue veterinary drug method using a new LC- triple quadrupole mass spectrometer system with high sensitivity and robustness for routine analysis. The method was evaluated using extracts of bovine muscle, salmon (fillet), and milk obtained using a modified QuEChERS sample preparation protocol. Secondly, examples will be shown to demonstrate how powerful HRAM MS technology can enhance quantitation and screening beyond targeted analysis and be a key problem-solving force in your laboratory.
Dave Borts, Assistant Professor, Department of Veterinary Diagnostic and Production Animal Medicine Iowa State University
Dave Borts joined the faculty at Iowa State University in March of 2016. He is an Assistant Professor in the Department of Veterinary Diagnostic and Production Animal Medicine and the Section Leader for the Analytical Chemistry Services unit of the Veterinary Diagnostic Laboratory, and holds courtesy appointments in the Biomedical Sciences Department and Interdisciplinary Toxicology Program at Iowa State. Dave received a BS in Chemistry from Iowa State University, an MS in Chemistry from the University of Michigan, and a PhD in Analytical Chemistry from Purdue University. Prior to his arrival at Iowa State, Dave worked in industry for 17 years with GlaxoSmithKline, BASF, and DuPont. During this time he was part of teams that brought a number of new products to market in the pharmaceutical and crop protection industries. Dave has expertise in a broad range of analytical and mass spectrometry applications including quantitative bioanalysis, structure elucidation, metabolomics, and ambient ionization techniques.
Ed George, Senior Applications Scientist, Environmental and Food Safety, Chromatography and Mass Spectrometry Thermo Fisher Scientific
Ed George has a BS in Chemistry from the University of Notre Dame with a concentration in Environmental Science. He worked for 15 years in the commercial environmental laboratory industry, where he was responsible for developing novel sample preparation, GC–MS/MS and LC–MS/MS analysis methods for a range of contaminants in water and solid wastes. He has participated in several collaborative method development projects with the US EPA. From 2005–2009, he worked for Varian, Inc. as an Application Lab Manager. Ed joined Bruker Daltonics in January 2010 as an applications chemist and later became Product Manager single quadrupole instruments. Ed joined Thermo Fisher Scientific in 2014 where he’s worked in the Environmental and Food Safety Vertical marketing team developing applications and solutions for triple quadrupole as well as high resolution mass spectrometers.
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