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This work is an update to Application Note 164 (featured in the United States Pharmacopeia (USP)) using fast separations and an HPIC system to reduce run times by 50%-- from 10 minutes to 5 minutes.
Understand the use of three different anion-exchange columns with amperometric detection to analyze common simple sugars, sugar alcohols, and glycols in pharmaceutical formulations.
Read about an IC-based method for the determination of ammonia (as ammonium) in sodium bicarbonate. The method performance characteristics were measured according to the requirements described in the USP General Chapter 1225 guidelines.
See how an IC method is developed to replace the titrimetric assay for potassium bitartrate in the United States Pharmacopeia (USP) Potassium Bitartrate monograph.
Study this alternative method for lithium citrate analysis that is automated, fast, and uses an aqueous mobile phase (eluent). IC offers a significant improvement to the existing assays because it can simultaneously determine lithium, sodium, calcium, and other common cations in a single injection.
See how this IC method developed for the assay of zinc oxide in sunscreen based on the method in the proposed zinc oxide monograph is demonstrated.
Get an understanding of the efficacy of the Thermo Scientific Dionex IonPac AS15-5µm column for the determination of fluoride in sodium fluoride tooth gel.
Evaluate how the Thermo Scientific™ Dionex™ CarboPac™ PA200 column for the separation of α, β, and γ-cyclodextrins and for the determination of β-CD according to the USP Betadex Sulfobutyl Ether Sodium monograph.
The goal of this work is to develop a simplified IC application in conjunction with mass-selective detection to facilitate the identification and quantification of highly polar aliphatic and unsaturated organic acids in pharmaceutical solutions.
Thank you for downloading our most popular pharmaceutical applications. Looking for more? Check out these additional resources:
- Ion Chromatography Tips and Tricks
- Polar and Ionic Components in Pharmaceutical and Biopharmaceutical Industry
- 5 Quick Tips to Develop and Improve Your Method
- Pharma & Biopharma Learning Center, including
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