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Initially considered as genomic “junk”, long noncoding RNAs (lncRNAs) have gained attention as critical regulators of coding RNA and alternative splicing. LncRNAs have been associated with tumorigenesis, tumor progression and metastasis, thus emerging as a new class of promising cancer biomarkers and targets for therapeutic agents.
Extracting robust expression data from clinical research samples represents a unique opportunity to find actionable biomarkers.