wf14843-SuperScript-Publication-Scavenger-Hunt

Did you know SuperScript™ Reverse Transcriptase was first introduced more than 25 years ago? That’s right—with over 35,000 publications to date, SuperScript Reverse Transcriptase (RT) has been used to synthesize cDNA from a wide range of RNA templates, from tumor tissue to Ebola virus.

In celebration of the use of SuperScript RT as an invaluable tool for molecular biology research, we invite you to join us on a very cool publication scavenger hunt. If you can find qualifying publications on SuperScript RT, you can enter to win SuperScript RT for your lab!**

It’s simple.

Every two months, we will highlight a selected application where SuperScript RT is used to synthesize cDNA. To join the hunt, find a publication relevant to the application and enter the citation using SuperScript RT. Up to 10 winners will be randomly drawn from the entries each month, and the winner can select to receive SuperScript VILO Master Mix or the new SuperScript IV First-Strand Synthesis System, 50 reactions. Very cool, indeed!

Let the hunt begin!

Skin cancer, the most common type of cancer, accounts for the majority of newly diagnosed cancer cases each year; more than the breast, prostate, lung and colon cancer cases combined, according to the Skin Cancer Foundation and the American Cancer Society, Cancer Facts and Figures 2015. The vast majority of skin cancer cases, referred to as keratinocyte carcinomas and melanomas, are fortunately very treatable when detected early. Research into causes, prevention and early treatment of skin cancer is being done throughout the world and RT-PCR represents one of the most common and important tests in cancer diagnosis. Here are some examples of publications citing the use of SuperScript RT in RT-PCR applications for the analysis and diagnosis of skin cancer.

  • Aissaoui, H etal. (2015) MDA-9/Synthenin is Essential for Factor VIIa-induced Signaling, Migration, and Metastasis in Melanoma Cells. J.Biol. Chem. 290: 3333- 3348. RT-PCR using SuperScript II Reverse Transcriptase
  • Romero A.I. etal (2014) Regulation of CD4+ NKG2D+ Th1 Cells in patients with metastatic melanoma treated with Sorafenib: role of IL-15Ra and NKG2D Triggering. Cancer Res. 74: 68-80. Total RNA isolated from melanoma cell, cDNA synthesized by SuperScript III Reverse Transcriptase followed by qPCR.

 

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 SuperScript III RT
 
 SuperScript VILO cDNA Synthesis Kit and Master Mix
 
 SuperScript II RT
 
 SuperScript RT
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 SuperScript VILO Master Mix (cat. 11755050)
 
 SuperScript IV first-strand synthesis system (cat. 18091050)