What can you get from high pressure ion chromatography?

What can you get from high pressure ion chromatography?

A new level of performance. We made sure each component of our IC systems was built to operate with ease at high backpressures. The speed and resolution achieved from Thermo Scientific™ HPIC™ high pressure ion chromatography system was worth the effort.

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What is high pressure ion chromatography?

Thermo Scientific™ Dionex™ HPIC™ systems redefine the way ion chromatography is performed due to their continuous operation up to 5000 psi when configured as a Reagent-Free™ (RFIC™) system. This feature allows the use of new high-efficiency 4μm particle-size columns, which provide better performance.


Why develop high pressure ion chromatography capabilities?

Many of our customers need higher resolution, and one can get significant gains in resolution by reducing an IC column’s particle size. While column efficiency doubles by reducing the particle size from 8µm to 4µm, the smaller particle size increases the column pressure four-fold. Dionex HPIC high pressure ion chromatography systems were designed to operate comfortably at these higher backpressures.

Featured Dionex column video

Dionex IonPac 4µm Columns, their features, and applications.


How can I balance resolution and speed in my Dionex HPIC system?

Our 4µm columns are available in capillary (0.4mm), microbore (2mm) and standard bore (4mm) inner diameters. Different lengths allow you to choose the optimum balance between resolution and throughput.

  • Use the longer, 250mm length 4µm particle size columns for higher resolution separations of complex sample matrices.
  • Use the shorter, 150 mm length 4µm particle size columns at higher flow rates to increase productivity without sacrificing performance.

What Dionex HPIC systems are available?

Integrated, plug-and-play high pressure ion chromatography systems
Dionex Integrion HPIC System Meet your routine ion analysis demands using the easy-to-use, reliable, integrated IC system
Dionex ICS-4000 Capillary HPIC System Perform high-resolution ion chromatography quickly and at less cost
Modular, highly configurable high pressure ion chromatography systems
Dionex ICS-5000+ Capillary HPIC System Get best-in-class resolution, speed, and sensitivity while saving time and eluent with this modular, high-pressure capillary ion chromatography system
Dionex ICS-5000+ Standard & Microbore HPIC System Get significant increases in resolution and throughput in this high-pressure modular IC system for standard bore and microbore columns
Dionex ICS-5000+ Hybrid HPIC System Simplify even the toughest IC x IC methods and trace analyses. Get best-in-class resolution, sensitivity, and throughput in a dual-channel, high-pressure system

What 4μm particle size IC columns are available?

Thermo Scientific™ Dionex™ IonPac™ 4 μm Particle-size IC Columns

IC Column Application Format
Dionex IonPac AS28-4µm Fast, high-resolution of trace concentrations of low molecular weight organic acids (glycolate, acetate) and inorganic anions Standard, microbore, and capillary
Dionex IonPac AS19-4µm High-resolution separation of oxyhalides and inorganic anions in complex sample matrices Standard, microbore, and capillary
Dionex IonPac AS11-HC-4µm  High-resolution separation of organic acids and inorganic anions in complex sample matrices Standard, microbore, and capillary
Dionex IonPac AS18-4µm  Fast, high-resolution separation of inorganic anions in diverse matrices Standard, microbore, and capillary
Dionex IonPac CS19-4µm Fast, high-resolution separation of cations and small polar amines in diverse matrices Standard, microbore, and capillary
Dionex IonPac CS12A-5µm  High-efficiency and fast analysis of mono- and divalent cations Standard, microbore, and capillary
Dionex CarboPac™ SA10-4µm IC Columns Direct quantification of nonderivatized carbohydrates in biofuels and food samples with minimal sample preparation using pulsed amperometric detection Standard and microbore
Dionex CarboPac SA10-Fast-4µm IC Columns Fast, direct quantification of nonderivatized carbohydrates in biofuels and food samples with minimal sample preparation using pulsed amperometric detection Standard and microbore
Dionex IonPac AS18-4µm  Fast, high-resolution separation of inorganic anions Standard, microbore, and capillary
Dionex IonPac AS22-Fast-4µm Fast high resolution separation of common inorganic anions Standard, microbore, and capillary
Dionex IonPac CS12A-5µm  High-efficiency and fast analysis of mono- and divalent cations Standard, microbore, and capillary

Can I use other particle size columns with HPIC instruments?

Yes, of course. Most IC column chemistries can be run on HPIC instruments. Basic column compatibility with instruments is as follows:

  • Capillary columns (0.25–0.40mm ID) are for use in instruments configured for capillary IC, such as the  Dionex ICS-4000 HPIC system or the Thermo Scientific™ Dionex™ ICS-5000+ HPIC capillary or hybrid system.
  • Standard bore and microbore columns (2–5 mm ID) are for use on the Dionex Integrion HPIC system or the Dionex ICS-5000+ HPIC capillary or hybrid system.
  • Applications using gradient separations with two or more eluent solutions on standard bore and microbore columns are run on the ICS-5000+ HPIC system configured for gradient separations.
  • Other HPIC systems support isocratic separations or gradient separations achieved by eluent generation.

 

Chromeleon CDS Software Resources

Here’s a collection of resources to learn about the feature sets that make this software both powerful and easy to use.