Virtual IC Column Separation Simulator
Discover the fastest, easiest, and most economical way to optimize IC separations.
Why optimize IC the hard way?
Seeking the best column and separation conditions for an IC analysis used to be a gamble. You had to guess where to start and which parameters to vary, never sure if you were headed in the right direction. You had to spend hours generating chromatograms, consuming samples and eluents while tying up your instrument and putting wear and tear on your pump, autosampler, and column.
Fast, risk-free optimization
The Virtual Column™ Separation Simulator eliminates the risks and hassles in optimizing IC separations by modeling their behavior in software, using known retention data and IC-specific retention algorithms. Specify the analytes you want to separate, choose the Thermo Scientific™ Dionex™ column and eluent system you want to model, and the Virtual Column Separation Simulator can find and display the optimal separation, together with a resolution map indicating the eluent concentration(s) required.
Easy answers to challenging questions
Want to shorten the run time, balance the separation of the peaks, or resolve a pair of difficult peaks? Simply click a command to find the conditions that will yield the fastest chromatogram with acceptable resolution, or the best spread of the peaks, or the best resolution of two specific peaks.
Solutions to cover your application needs
The Virtual Column Separation Simulator models all of the most popular Dionex anion-exchange and cation-exchange columns, using retention data for hundreds of analytes—you don't spend any time "training" the software. Use the Virtual Column Separation Simulator in the Thermo Scientific™ Dionex™ Chromeleon™ 7.2 Chromatography Data System (CDS) software’s powerful Application Wizard and generate the exact Control Program and Quantification method for your newly developed separation.
Develop gradient separations as easily as isocratic separations
Gradient separations can greatly increase the capability and performance of ion chromatography, but until recently, only experts were willing to try them. Now with a Virtual Column Complete license and Reagent-Free™ IC (RFIC™) systems, everyone can take advantage of the power of gradient ion chromatography. A few minutes invested into modeling your application under gradient conditions could save you hundreds of hours per year.
Optimize separation of your specific analytes
Speed up your separations
Isolate a specific peak of interest
Workstation or client station with Chromeleon CDS, version 6.6 or higher. Gradient simulations requires Chromeleon CDS, version 6.7 or higher.
Anions: IonPac™ AS4A-SC, AS9-HC, AS10, AS11,AS11-HC, AS12A, AS14, AS14A, AS15, AS16, AS17, AS18, AS19, AS20, AS22, AS24 Cations: CS12A, CS16, CS17, CS18 Carbohydrates: CarboPac™ PA20
Methodologies (traditional and Reagent-Free™)
Anions: gradient hydroxide, isocratic hydroxide, isocratic carbonate/bicarbonate Cations: gradient methanesulfonic acid (MSA), isocratic MSA Carbohydrates: isocratic hydroxide
Minimum resolution, normalized resolution product, optimize for specific analyte
Find fastest chromatogram, find global optimum, apply product test conditions.
User-Editable Peak Values
Area, asymmetry, theoretical plates
Operating temperature, flow rate, void volume
An unlimited number of optimization projects can be saved, loaded, modified, and resaved.
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