Ion Chromatography Systems

Resolving ion analysis

Gain confidence that your Ion Chromatography (IC) systems will generate meaningful results when you need them with Thermo Scientific IC systems. Providing unique technologies, unparalleled robustness and capabilities, these systems enable you to focus on what matters to you – your work.

We have you covered from routine to complex analyses with difficult goals, Thermo Scientific Dionex IC systems allow you to overcome any challenges in ion analysis to obtain reliable results, faster and easier.

  • Robustness and simplicity for routine analyses
  • Unique technology, like Reagent Free Ion Chromatography, increases reproducibility and ease of use
  • High Pressure Ion Chromatography allows the use of smaller particle size column packings which improves peak resolving power and shortens run times
  • Advanced technology enables you to customize your modular and upgradeable systems to solve highly complex separations

We offer a full range of IC instruments and technologies to fit what is important to you and the needs of your laboratory.

Explore the benefits of Thermo Fisher Dionex IC systems for your ion analyses

Eluent generation

Choose the consistency and labor savings you need

Since the advent of ion chromatography, eluent choice has been one of the key factors affecting the usability and performance of IC systems. Today, there is probably a standard eluent for your application, but you still have a lot of choices that affect usability. Read on to discover some of the considerations when choosing how to prepare your eluent or watch the educational video, below.

Technique Considerations
Manual Preparation
Operator prepares an eluent concentrate and then dilutes
Low upfront expense, but limited application choices
Manual Dilution
Operator dilutes an eluent concentrate purchased from vendor
Reduced operator input, but applications are restricted to those supported by available eluent concentrates
Automated Dilution *
System automatically dilutes eluent concentrate with water off-line
Reduced operator input, but increased complexity in plumbing and poor performance when concentrations are changed
Automated Eluent Proportioning
Accurately timed valves are rapidly switched to allow combinations of source eluents
Broad application coverage, but costly and complex to maintain.
Eluent Generation
Purified eluent is created in-line and on-demand
Least operator input, but some application restrictions.
Dual Eluent Generation
Multiple purified eluents are created and combined in line and on demand
Least operator input, broad application coverage.

* Not offered on Thermo Scientific Dionex Ion Chromatography systems due to the availability of solutions with superior performance at the same or lower cost.
† Available only on Thermo Scientific Dionex Ion Chromatography systems


Suppression

Choose the level of sensitivity, peace of mind, and labor savings that you need

Suppressors are necessary for most IC applications in order to reduce background conductivity and enhance analyte response. With modern suppressors, it is even possible to measure analyte concentrations in the ng/L range. (Download  Thermo Scientific Technical Note 72206 for details.)

Your choice of suppressor should be based on the requirements of your application, as well as your confidence and time to spend on maintenance of the suppressor and regenerant delivery system. For a comparison of suppressed vs. nonsuppressed conductivity detection, download  Thermo Scientific Application Note 157.

Technique Considerations
Unsuppressed
Eluent and sample flow directly from the separator to the detector
Simplest setup, but very low sensitivity and highly restricted application conditions. Most methods do not allow unsuppressed conductivity
Packed-Bed Chemically Regenerated Suppressor *
Large quantity of high capacity ion exchange resin, periodically regenerated offline
Increased sensitivity, but poor chromatography (due to dead volume) and high downtime. Highly restricted application conditions to minimize regeneration needs.
Auto-switching Suppressor *
Multiple packed-bed suppressor cartridges, switched to a different cartridge after every injection.
Reduced labor and downtime, but limited suppression capacity, no traceability, and requires regenerant preparation and delivery system
Continuously Regenerated Suppressor
Ion-selective membrane separating eluent and chemical regenerant chambers; continuous suppression as long as regenerant is flowing
“Infinite” capacity, but still requires regenerant preparation and delivery system
Electrolytically Regenerated Suppressor
Similar to the continuously regenerated suppressor, but creates regenerant online through electrolysis of water.
Reagent and labor-free, slightly lower sensitivity and some restrictions on solvents in eluent.
Dynamically Regenerated Suppressor
Similar to the Electrolytically Regenerated Suppressor, but continuously adapts the creation of regenerant ions to the current conditions
Reagent and labor-free, always optimized for sensitivity, even under eluent concentration gradients. Some restrictions on solvents in the eluent.

* Not offered on Thermo Scientific Dionex Ion Chromatography systems. Instead, we offer solutions with superior performance at the same or lower cost.
† Available only on Thermo Scientific Dionex Ion Chromatography systems


Sample preparation: Particulate removal

Choose the system protection, performance, and labor savings you need

Some ion chromatography sample matrices may carry high quantities of particulate matter, requiring some form of particulate removal to protect other components of the IC system. The particulate removal option you choose has implications for balancing performance, simplicity, and level of protection. Take a look at the common challenges and misconceptions about particulate removal and discover the solutions available to meet your application needs.

Technique Considerations
Vacuum Filtration
Filtration apparatus applies a vacuum to assist in drawing a sample through a filter
Very high labor requirements
Syringe Filters
Single-use, disposable filters that are attached directly to a luer-lock syringe after sample aspiration
No carryover, but high cost and labor requirements
Tangential-Flow Microfiltration
Continually passes a high volume of sample across a filter membrane with a negative pressure on the other side
Labor saving, but potential for carryover and requires large sample volume and additional dual-channel pump
Stopped-Flow Dialysis
Allows solutes to move down a concentration gradient across a semipermeable membrane into a receiving solution
Labor saving, but potential for carryover and requires additional two dual-channel pumps
Sample Vial Filter Caps
Directly inserted into vials and filter the sample during aspiration
Labor saving and no carryover, but single use
High-Pressure Inline Filters
Low-volume filters placed into the high-pressure flow path immediately after the injection valve
Labor saving, low maintenance, no sample loss, and no additional instrumentation required
Dual Inline Filters with Backflush
Two high-pressure inline filters installed on a valve to allow a backflush after each injection
Two high-pressure inline filters installed on a valve to allow a backflush after each injection

Thermo Scientific Dionex Easion Ion Chromatography (IC) System

  • Get up and running quickly – Everything you need to get started, including columns, suppressor, eluent concentrate, and regenerant concentrate; no additional pumps or equipment required.
  • Pre-configured analysis kits – Our kits take the guesswork out of system configuration for anions or cations.
  • Space-saving footprint – Dionex Easion fits anywhere that you have a bit of bench space.
  • Industry-leading quality and reliability – You can have confidence in your purchase decision and assurance in your satisfaction for years to come.
  • Simple operation and maintenance - With Dionex Easion there are no extra items to change or maintain.
  • Membrane-based chemical suppression - This system ensures maximum uptime and reduces baseline drift to minimize sample-to-sample variability.
Thermo Scientific Dionex Easion Ion Chromatography (IC) System

 

 

 

 

 

  1. Eluent and Regenerant Tray
  2. Dual Piston PEEK Isocratic Pump
  3. Fixed Loop Injection Valve
  4. Worry-free Chemical Suppressor
  5. Thermally Controlled Conductivity Detector

Supported by Chromeleon 7.2.10 MuA

Thermo Scientific Dionex Aquion Ion Chromatography (IC) System

The Dionex Aquion IC system brings a new level of robustness to anion and cation analyses through engineered simplicity.

  • Anyone can perform the required analyses regardless of chromatography background - Aquion is very easy to setup and simple to use which makes it perfect for running routine methods
  • Reduce the risk of rerunning samples or misidentifying components – Automatic eluent degassing and column temp. control ensures retention time and peak area reproducibility
  • Minimal user interaction required to operate and maintain – Spend more time on other lab tasks instead of in front of your IC
  • Compact with small footprint – Saves bench space in your lab
  • Be confident in your results by reducing contamination risks and providing compatibility with a full range of IC eluents – PEEK flow paths, metal free
  • Optimize the system for your analysis – Accommodates a wide variety of columns and suppressors

Thermo Scientific Dionex Integrion Ion Chromatography (IC) System

The Dionex Integrion IC makes ion chromatography virtually automatic. Just add water to the system and Integrion does the rest because it will generate your eluent and automatically take care of counterion suppression. Integrion is versatile for analyzing environmental contaminates, sugars and simple carbohydrates in food and beverages, ionic compounds in pharmaceuticals and ions of concern in industrial and petrochemical applications. This small integrated system can also be upgraded as your lab’s needs change.

  • Increase method precision, improve chromatography using gradient separations as well as reduce maintenance costs and downtime – with reagent free ion chromatography eluents are automatically generated and purified using an electrolytic process after the pump. To operate the system, just add water and enter your eluent composition into the software. The system can be started and operated using the push of a button and requires very little user interaction. 
  • Allows for better separations – Using small particle column technology, you can get better resolution between your components and can help to shorten run times. 
  • Reduce maintenance costs and troubleshooting time – When using eluent generation, no harsh chemicals or salts are exposed the pump, increasing the lifetime of the pump parts, like seals and check valves. Also, remote system monitoring can proactively detect any issues before performance is affected
  • Quick and easy consumables replacement – Using tool-free Viper fittings, columns and other consumable items are changed sing a finger tight connection that ensures a proper fit every time, avoiding any dead volumes which would adversely affect chromatography.       
  • Adapts to your lab’s needs – Integrion can be upgraded as your analytical challenges and assays change. Conductivity or amperometry detectors are available and can be added after purchase. Eluent generation can also be added at any time.  
  • Saves bench space in your lab – Compact with small footprint
  • High pressure ion chromatography ready
Consumables Device Monitor

Consumables Device Monitor

Provides positive identification of a consumable's performance metrics, preventing consumable installation errors and mismatches by automatically logging consumable use and performance.

Detectable tablet* with local language support

Detectable tablet* with local language support

Flexible access to IC controls that speak your language

* The wireless transmitter devices may not be authorized as required by the laws of your country; and these features will not be, offered for sale or lease, or sold or leased, until proper authorization is obtained. Please consult your local sales representative for details.

Automated Eluent Generation (EG™)

Automated Eluent Generation (EG™)

Eliminate human errors associated with manual eluent preparation and improve method reproducibility from operator-to-operator and lab-to-lab. The Dionex Integrion IC system brings consistent results to all your applications. In this case, 100 injections of a simple sugar mixture are highly reproducible.

Wide range of column support

Wide range of column support

Choose the column sizes you need for your applications, including smaller-particle-size 4 µm columns that provide faster run times and better resolution.

Thermo Scientific Dionex ICS-4000 Ion Chromatography (IC) System

Thermo Scientific Dionex ICS-4000 is a dedicated capillary system which always on and ready and provides an easy workflow when you need the quickest time to result.

  • Gets you answers very quickly – Since the system is always running, daily calibrations are not required. Simply inject your check standard and sample.
  • Walk up, on-demand analysis – The system can set up in an open access environment allowing anyone to get results. No formal laboratory training is required to get the answers you need. 
  • Saves on eluents costs – Uses a tiny amount of eluent which allows the system to always be running.  Typical eluent usage is less than 0.5 Liters per month.  
  • Get the most out of limited sample volumes – Capillary scale IC systems only need a small amount of sample.
  • Easy changing of consumables – All consumables are cartridge based using the Dionex IC Capillary Cube
  • Saves bench space in your lab – Compact with small footprint
  • High pressure ion chromatography ready
  • Best suited for dedicated routine applications

Videos

Thermo Scientific Dionex ICS-6000 Ion Chromatography (IC) System

The Dionex ICS-6000 is designed to perform complex ion chromatography analysis, from routine QC/QA analyses to cutting edge research as well as trace analysis. A highly flexible ion chromatography (IC) system provides you with the freedom to develop, explore, and run different methods simultaneously. The ICS-6000 can run any IC application.

  • Perform Complex Analyses – The ICS-6000 is modular and can be custom tailored to fit your needs. Since the ICS-6000 is a dual channel system, the configuration flexibility is beyond any other ion chromatograph. 
  • Unmatched productivity – Use both channels together to simultaneously analyze very different components from the same sample, such as anions and cations together. 
  • Be ready for anything – New modules can be added as you need to expand your analytical capabilities and analyze new ions or compounds. Each channel can have a very different configuration, whether its standard to capillary scale, different detectors, or various pumping capabilities, you will always have what you need for any IC application.
  • Achieve lower detection levels – Can be configured as a 2D system or use the integrated Automation Manager to do post column reactions to achieve ultimate sensitivity. 
  • High pressure ion chromatography ready

Pump 1 – Configured as Isocratic

  1. Eluent Pump
  2. Eluent Degasser (Isocratic)
  3. Rear Seal Wash

Pump 2

  1. Quaternary Gradient Proportioning Value
  2. Eluent Degasser (Quaternary)
  3. Eluent Pump

Dual Eluent Generator

  1. Eluent generator 1 configured with analytical scale eluent cartridge
  2. Eluent generator 2 configured with capillary scale eluent cartridge

Detector Compartment

  1. Injection Valves
  2. Thermally Controlled Column Compartment
  3. Suppressor
  4. Conductivity Detector
  5. Amperometric Detector
  6. IC Cube

Autosampler

  1. AS-AP (shown) or AS-DV (optional)

Accelerate your productivity

The Dionex ICS-6000 HPIC system offers a suite of features to get you from sample to results faster and keep your laboratory running seamlessly, including:

  • High Pressure Ion Chromatography (HPIC): Columns featuring 4 μm particles to optimize chromatographic efficiency with shorter sample run times and/or improved resolution
  • Automated eluent preparation using Reagent-Free Ion Chromatography-Eluent Generation (RFIC-EG) technology
  • Single- and dual-channel system configuration options
  • Finger-tight connections that minimize dead volume and make connections easier
  • Automated tracking of the usage and performance of IC consumables
  • Tablet control of the IC system, to easily monitor sample runs
  • An optional, always ready capillary IC configuration to perform 24/7 sample analysis

High-pressure ion chromatography (HPIC)

The Dionex ICS-6000 HPIC system is high-pressure-capable up to 5000 psi to allow the use of 4 μm-particle-size IC columns, available in 150 or 250 mm lengths. The 150 mm-length columns decrease run times, while maintaining chromatographic resolution when compared to 10 μm-particle-size columns. The 250 mm-length columns offer improved peak resolution.

Automated eluent generation (RFIC)

The RFIC-EG module of the Dionex ICS-6000 HPIC system uses Thermo Scientific Dionex EGC Eluent Generator Cartridges to electrolytically generate high-purity hydroxide, carbonate, bicarbonate, or methanesulfonic acid (MSA) eluents at the concentration you specify. A high-purity source of deionized water is the only requirement. RFIC-EG provides control for isocratic or gradient conditions with unmatched method reproducibility and accuracy. Improved control of the EG cartridge also minimizes system start up times, increasing productivity.

Single- or dual-channel configuration

When you need to run two different analyses simultaneously on a single sample or analyze two different samples concurrently, the Dionex ICS-6000 HPIC system can easily be converted to a dual-channel system.

Easy-to-install finger-tight fittings

Achieving consistent low-dead-volume connections is critical for maintaining optimum chromatographic efficiency. Conventional fittings can increase column broadening due to incorrect positioning of the ferrule, leading to reduced efficiencies and poor peak shapes. Thermo Scientific Dionex IC PEEK Viper fittings provide consistent, finger-tight connections with virtually zero dead volume and require minimal training time.

Consumables Device Monitor

The Consumables Device Monitor automatically identifies and tracks the installation time, use, and performance metrics of your IC consumables. Use this feature to prevent consumable installation errors, schedule preventive maintenance, and manage consumable usage, ultimately minimizing system downtime and improving productivity. It is designed to:

  • Keep metrics information with the consumable, regardless of the system in which it is installed
  • Simultaneously monitor up to 16 key performance metrics on up to 25 different consumables
  • Verify consumable performance against product specifications and production quality assurance data

Tablet control

The Dionex ICS-6000 HPIC system comes equipped with a tablet with an intuitive interface, enabling direct local control of the system and its status. Use the tablet or a desktop computer for system setup, maintenance, troubleshooting, and routine monitoring. The tablet interface is available in 11 different languages to customize your user experience. Additionally, the tablet enables you to:

  • Communicate with the instrument via secured WiFi or a wired connection
  • Control and monitor one instrument at a time, with easy instrument switching
  • Access consumable installation guides and troubleshooting knowledge base
Dionex ICS-6000 HPIC system

The Dionex ICS-6000 HPIC system is available in a variety of configurations, including:

  • Standard Bore – Uses traditional ion chromatography column diameters, about 4mm, and flow rates, at around 1 ml/min. Standard bore scale IC covers most ion chromatography applications.
  • Microbore – Microbore scale IC reduces eluent consumption as well as waste generated by using 2 mm diameter columns and consumables. Flow rates average between 0.2 to 0.5 mL/min. Microbore IC also scales down required injection volumes and can provide some sensitivity gains.
  • Capillary - Capillary IC scales down column size, injection volumes, and flow rates by a factor of 10 to 100. Since flow rates are very low, For a 0.4 mm ID column, it would be about 10 µL/min, the system is easily operated 24 /7. This means less frequent calibration, and thus less operator intervention. Capillary IC consumes only 15 mL of water a day, translating into 5.25 L a year of eluent usage.
Format Capillary Microbore Standard
Typical flow rate range 5-20 µL/min 0.2-0.5 mL/min 1-2 mL/min
Column i.d. supported 0.2-0.6 mm 1-3 mm 3-7 mm
Typical yearly eluent usage 5.25 L 131 L 525 L

Multiple, flexible detector options

The Dionex ICS-6000 HPIC system supports a variety of detectors, including:

  • Suppressed conductivity
  • Electrochemical, including DC amperometry and integrated amperometry
  • UV-Vis absorbance, including variable wavelength and photodiode array
  • Inductively coupled plasma mass spectrometry (ICP-MS)
  • Mass spectrometry (MS)

Discover ion chromatography-mass spectrometry

The Dionex ICS-6000 HPIC system is compatible with single quadrupole, triple quadrupole, and high-resolution accurate-mass (HRAM) Thermo Scientific Orbitrap mass analyzer-based mass spectrometers for performing powerful ion chromatography-mass spectrometry (IC-MS) analyses.

Solve complex analysis challenges

The Dionex ICS-6000 HPIC system can address the full range of IC analysis applications. It is suitable for techniques from 2-D ion chromatography for trace-level analysis to high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) for complex carbohydrate analyses.

Which Dionex ICS-6000 HPIC system configuration is best for you?

 

Dionex ICS-6000 Standard Bore and Microbore HPIC Systems

Dionex ICS-6000 Capillary HPIC Systems

Dionex ICS-6000 Hybrid HPIC System

Major benefit

  Request quote Request quote Request quote  
Column configurations Two standard bore 4 mm, two microbore 2 mm, or one of each column Two capillary 0.4 mm columns One standard bore and one capillary, or one microbore and one capillary column Can run two different analyses simultaneously
Column compartment Dionex ICS-6000 DC Detector/Chromatography Compartment Dionex ICS-6000 Capillary IC Cube Dionex ICS-6000 Capillary IC Cube Allows easy column installation and connections
Column choices Offers broad variety of quality columns
Detectors (standard) Can be used in most common IC applications
Detectors (optional) Allows addition of detector for special applications
6000 psi pumps Can perform high pressure IC or, with dual pumps, 2D-IC
Eluent generator Capillary EG lasts 18 months; uses 5.25L water/day
Autosampler compatibility Offers a variety of cost and application options
CDS software Provides, power, simplicity and convenience

Ion Chromatography Mass Spectrometry (IC-MS)

Increase the power of IC with MS detection

Utilize mass detection when you need to ensure analytical confidence and dramatically improve the detection capability of your Thermo Scientific Dionex Integrion or ICS-6000 HPIC system. Ion chromatography with mass spectrometry (IC-MS) maximizes the ability to detect and quantify unexpected co-elutions of components and to confirm trace components.

  • Obtain higher sensitivity – MS detection is more sensitive than traditional IC detection techniques like conductivity and amperometry.
  • Get very accurate quantification – Mass spec gives excellent quantitation with a wide linear dynamic range
  • Have more confidence in your results - Peak identity and purity confirmation is very easy with mass spectrometry because you can focus your detection on selected masses.
  • Unmatched screening capabilities – Mass spec not only has sensitivity advantages but can find compounds in complex matrixies, in some cases, even when you are not looking for them.

Single Quadrupole IC-MS

Easily master MS for your IC applications

Triple Quadrupole IC-MS

Need sensitive, fast, and robust quantitation of a variety of molecule types? For complex samples, the high sensitivity and selectivity of MS/MS using selected reaction monitoring (SRM) provides the most precise and accurate quantitation using IC-MS.

Increase productivity, with reliability and robustness, for labs focused on performing targeted quantitation with the Thermo Scientific TSQ Fortis Triple Quadrupole Mass Spectrometer. This system makes it easier to meet today's demands by confidently answering more complex questions per sample, while achieving reproducible results.

Orbitrap IC-MS

Thermo Scientific Orbitrap mass spectrometers generate high-resolution and accurate-mass data, thereby enhancing sensitivity in trace analyte detection, characterization, and quantitation. That's why they are used in research applications—in particular, life science applications such as metabolomics.

Get a superior combination of scan speed, high resolution, mass accuracy, spectral quality and sensitivity for untargeted or targeted screening and a broad range of qualitative and quantitative applications in environmental, food safety and metabolomics.

Use this system for IC-MS in life science metabolomics research to analyze the most challenging low-abundance, high-complexity samples, to identify more compounds faster, quantify more accurately, and to elucidate structures more thoroughly.

Which mass spectrometer do I choose?

Mass Spectrometer Analyzer Mode of Operation MS MS/MS Sensitivity Peak Confirmation Structural Elucidation
ISQ EC MS Quadrupole Single ion monitoring (SIM)
TSQ Altis MS Triple Quadrupole Selected reaction monitoring (SRM)
TSQ Quantis MS Triple Quadrupole Selected reaction monitoring (SRM)
Q Exactive MS Orbitrap mass analyzer High Resolution Accurate Mass (HRAM)
Orbitrap Fusion MS Orbitrap mass analyzer High Resolution Accurate Mass (HRAM)
  = Not applicable   = Poor   = Good   = Better   = Best

Reduce the time and labor for determination of corrosive halogens and sulfur in difficult samples by using the Thermo Scientific Combustion Ion Chromatography (CIC) system. This combustion IC system eliminates complex sample preparation steps using an automated method that is highly sensitive, easy-to-use, saves time, and produces fewer environmental contaminants than other sample preparation procedures. Use the CIC system for applications such as the analysis of corrosive halogen, sulfur determination, and halide speciation.

  • Save time and labor – The system is fully automated which allows more time to be spent on other tasks.
  • Improved reproducibility – Automation improves analytical performance
  • Increased lab safety - Pyrohydrolysis eliminates the need to dispose of hazardous chemicals used in acid digestions or back extractions.
Combustion Ion Chromatography System

Major applications

  • Per and Poly-Fluoroalkyl substances PFAS
  • Sulfur, Chloride, Fluoride, and Bromine in plastics
  • Chloride, Fluoride, Bromine in pharmaceutical raw materials and finished ingredients
  • Chloride in epoxy resins
  • Chloride, Fluoride, and Sulfur in liquid petroleum gas
  • Bromine in disposable (one-time use) polymers
  • Chloride in lubricating oil
  • Fluorine, Bromine, and Iodine in soil samples
  • Fluorine in ores
  • Chloride and Fluorine in aluminum powder
  • Chloride and Sulfur in coal

Disc-IC — fully automated high throughput solution for water analysis

Unique and fully automated DISC-IC combines the power of direct measurement, discrete analysis, and ion chromatography to support comprehensive water analysis workflow. Disc-IC offers a complete solution for wet chemical and ion analysis needs offering a highest flexibility, sample throughput options that reduces overall cost per analysis. For growing laboratories that perform routine analysis while experiencing increased demand for routine wet chemical analysis, Thermo Scientific Gallery discrete analyzers automates labor-intensive and time-consuming wet chemical tests. Thermo Scientific Dionex Ion Chromatography (IC) systems automates the anions and cations analysis.

Disc-IC provide true walk-away solution for comprehensive ground water, process water and waste water analysis and performs unattended large sample series analysis.

Gallery or Gallery Plus with ECM Module
Gallery or Gallery Plus with ECM Module
ICS 6000 or Integrion or ICS 4000
ICS 6000 or Integrion or ICS 4000
Direct measurement: pH, Conductivity

Titration Parameters: Alkalinity, Total Hardness
Fast Anions: Fluoride, Chloride, Nitrite, Nitrate, Bromide, Phosphate and Sulfate

Standard anions and oxyhalide analysis
Advanced Wet Chemistry Parameters: Silica, Total phosphate, TKN, TON, Urea, Total Phenol, Total Cyanide, Sulfide, Hexavalent chromium, total iron, Zinc, Boron and organic acids Standard Cations: Lithium, Sodium, Ammonium, Potassium, Calcium and Magnesium

Standard cations and amines analysis

Thermo Scientific Dionex Easion Ion Chromatography (IC) System

  • Get up and running quickly – Everything you need to get started, including columns, suppressor, eluent concentrate, and regenerant concentrate; no additional pumps or equipment required.
  • Pre-configured analysis kits – Our kits take the guesswork out of system configuration for anions or cations.
  • Space-saving footprint – Dionex Easion fits anywhere that you have a bit of bench space.
  • Industry-leading quality and reliability – You can have confidence in your purchase decision and assurance in your satisfaction for years to come.
  • Simple operation and maintenance - With Dionex Easion there are no extra items to change or maintain.
  • Membrane-based chemical suppression - This system ensures maximum uptime and reduces baseline drift to minimize sample-to-sample variability.
Thermo Scientific Dionex Easion Ion Chromatography (IC) System

 

 

 

 

 

  1. Eluent and Regenerant Tray
  2. Dual Piston PEEK Isocratic Pump
  3. Fixed Loop Injection Valve
  4. Worry-free Chemical Suppressor
  5. Thermally Controlled Conductivity Detector

Supported by Chromeleon 7.2.10 MuA

Thermo Scientific Dionex Aquion Ion Chromatography (IC) System

The Dionex Aquion IC system brings a new level of robustness to anion and cation analyses through engineered simplicity.

  • Anyone can perform the required analyses regardless of chromatography background - Aquion is very easy to setup and simple to use which makes it perfect for running routine methods
  • Reduce the risk of rerunning samples or misidentifying components – Automatic eluent degassing and column temp. control ensures retention time and peak area reproducibility
  • Minimal user interaction required to operate and maintain – Spend more time on other lab tasks instead of in front of your IC
  • Compact with small footprint – Saves bench space in your lab
  • Be confident in your results by reducing contamination risks and providing compatibility with a full range of IC eluents – PEEK flow paths, metal free
  • Optimize the system for your analysis – Accommodates a wide variety of columns and suppressors

Thermo Scientific Dionex Integrion Ion Chromatography (IC) System

The Dionex Integrion IC makes ion chromatography virtually automatic. Just add water to the system and Integrion does the rest because it will generate your eluent and automatically take care of counterion suppression. Integrion is versatile for analyzing environmental contaminates, sugars and simple carbohydrates in food and beverages, ionic compounds in pharmaceuticals and ions of concern in industrial and petrochemical applications. This small integrated system can also be upgraded as your lab’s needs change.

  • Increase method precision, improve chromatography using gradient separations as well as reduce maintenance costs and downtime – with reagent free ion chromatography eluents are automatically generated and purified using an electrolytic process after the pump. To operate the system, just add water and enter your eluent composition into the software. The system can be started and operated using the push of a button and requires very little user interaction. 
  • Allows for better separations – Using small particle column technology, you can get better resolution between your components and can help to shorten run times. 
  • Reduce maintenance costs and troubleshooting time – When using eluent generation, no harsh chemicals or salts are exposed the pump, increasing the lifetime of the pump parts, like seals and check valves. Also, remote system monitoring can proactively detect any issues before performance is affected
  • Quick and easy consumables replacement – Using tool-free Viper fittings, columns and other consumable items are changed sing a finger tight connection that ensures a proper fit every time, avoiding any dead volumes which would adversely affect chromatography.       
  • Adapts to your lab’s needs – Integrion can be upgraded as your analytical challenges and assays change. Conductivity or amperometry detectors are available and can be added after purchase. Eluent generation can also be added at any time.  
  • Saves bench space in your lab – Compact with small footprint
  • High pressure ion chromatography ready
Consumables Device Monitor

Consumables Device Monitor

Provides positive identification of a consumable's performance metrics, preventing consumable installation errors and mismatches by automatically logging consumable use and performance.

Detectable tablet* with local language support

Detectable tablet* with local language support

Flexible access to IC controls that speak your language

* The wireless transmitter devices may not be authorized as required by the laws of your country; and these features will not be, offered for sale or lease, or sold or leased, until proper authorization is obtained. Please consult your local sales representative for details.

Automated Eluent Generation (EG™)

Automated Eluent Generation (EG™)

Eliminate human errors associated with manual eluent preparation and improve method reproducibility from operator-to-operator and lab-to-lab. The Dionex Integrion IC system brings consistent results to all your applications. In this case, 100 injections of a simple sugar mixture are highly reproducible.

Wide range of column support

Wide range of column support

Choose the column sizes you need for your applications, including smaller-particle-size 4 µm columns that provide faster run times and better resolution.

Thermo Scientific Dionex ICS-4000 Ion Chromatography (IC) System

Thermo Scientific Dionex ICS-4000 is a dedicated capillary system which always on and ready and provides an easy workflow when you need the quickest time to result.

  • Gets you answers very quickly – Since the system is always running, daily calibrations are not required. Simply inject your check standard and sample.
  • Walk up, on-demand analysis – The system can set up in an open access environment allowing anyone to get results. No formal laboratory training is required to get the answers you need. 
  • Saves on eluents costs – Uses a tiny amount of eluent which allows the system to always be running.  Typical eluent usage is less than 0.5 Liters per month.  
  • Get the most out of limited sample volumes – Capillary scale IC systems only need a small amount of sample.
  • Easy changing of consumables – All consumables are cartridge based using the Dionex IC Capillary Cube
  • Saves bench space in your lab – Compact with small footprint
  • High pressure ion chromatography ready
  • Best suited for dedicated routine applications

Videos

Thermo Scientific Dionex ICS-6000 Ion Chromatography (IC) System

The Dionex ICS-6000 is designed to perform complex ion chromatography analysis, from routine QC/QA analyses to cutting edge research as well as trace analysis. A highly flexible ion chromatography (IC) system provides you with the freedom to develop, explore, and run different methods simultaneously. The ICS-6000 can run any IC application.

  • Perform Complex Analyses – The ICS-6000 is modular and can be custom tailored to fit your needs. Since the ICS-6000 is a dual channel system, the configuration flexibility is beyond any other ion chromatograph. 
  • Unmatched productivity – Use both channels together to simultaneously analyze very different components from the same sample, such as anions and cations together. 
  • Be ready for anything – New modules can be added as you need to expand your analytical capabilities and analyze new ions or compounds. Each channel can have a very different configuration, whether its standard to capillary scale, different detectors, or various pumping capabilities, you will always have what you need for any IC application.
  • Achieve lower detection levels – Can be configured as a 2D system or use the integrated Automation Manager to do post column reactions to achieve ultimate sensitivity. 
  • High pressure ion chromatography ready

Pump 1 – Configured as Isocratic

  1. Eluent Pump
  2. Eluent Degasser (Isocratic)
  3. Rear Seal Wash

Pump 2

  1. Quaternary Gradient Proportioning Value
  2. Eluent Degasser (Quaternary)
  3. Eluent Pump

Dual Eluent Generator

  1. Eluent generator 1 configured with analytical scale eluent cartridge
  2. Eluent generator 2 configured with capillary scale eluent cartridge

Detector Compartment

  1. Injection Valves
  2. Thermally Controlled Column Compartment
  3. Suppressor
  4. Conductivity Detector
  5. Amperometric Detector
  6. IC Cube

Autosampler

  1. AS-AP (shown) or AS-DV (optional)

Accelerate your productivity

The Dionex ICS-6000 HPIC system offers a suite of features to get you from sample to results faster and keep your laboratory running seamlessly, including:

  • High Pressure Ion Chromatography (HPIC): Columns featuring 4 μm particles to optimize chromatographic efficiency with shorter sample run times and/or improved resolution
  • Automated eluent preparation using Reagent-Free Ion Chromatography-Eluent Generation (RFIC-EG) technology
  • Single- and dual-channel system configuration options
  • Finger-tight connections that minimize dead volume and make connections easier
  • Automated tracking of the usage and performance of IC consumables
  • Tablet control of the IC system, to easily monitor sample runs
  • An optional, always ready capillary IC configuration to perform 24/7 sample analysis

High-pressure ion chromatography (HPIC)

The Dionex ICS-6000 HPIC system is high-pressure-capable up to 5000 psi to allow the use of 4 μm-particle-size IC columns, available in 150 or 250 mm lengths. The 150 mm-length columns decrease run times, while maintaining chromatographic resolution when compared to 10 μm-particle-size columns. The 250 mm-length columns offer improved peak resolution.

Automated eluent generation (RFIC)

The RFIC-EG module of the Dionex ICS-6000 HPIC system uses Thermo Scientific Dionex EGC Eluent Generator Cartridges to electrolytically generate high-purity hydroxide, carbonate, bicarbonate, or methanesulfonic acid (MSA) eluents at the concentration you specify. A high-purity source of deionized water is the only requirement. RFIC-EG provides control for isocratic or gradient conditions with unmatched method reproducibility and accuracy. Improved control of the EG cartridge also minimizes system start up times, increasing productivity.

Single- or dual-channel configuration

When you need to run two different analyses simultaneously on a single sample or analyze two different samples concurrently, the Dionex ICS-6000 HPIC system can easily be converted to a dual-channel system.

Easy-to-install finger-tight fittings

Achieving consistent low-dead-volume connections is critical for maintaining optimum chromatographic efficiency. Conventional fittings can increase column broadening due to incorrect positioning of the ferrule, leading to reduced efficiencies and poor peak shapes. Thermo Scientific Dionex IC PEEK Viper fittings provide consistent, finger-tight connections with virtually zero dead volume and require minimal training time.

Consumables Device Monitor

The Consumables Device Monitor automatically identifies and tracks the installation time, use, and performance metrics of your IC consumables. Use this feature to prevent consumable installation errors, schedule preventive maintenance, and manage consumable usage, ultimately minimizing system downtime and improving productivity. It is designed to:

  • Keep metrics information with the consumable, regardless of the system in which it is installed
  • Simultaneously monitor up to 16 key performance metrics on up to 25 different consumables
  • Verify consumable performance against product specifications and production quality assurance data

Tablet control

The Dionex ICS-6000 HPIC system comes equipped with a tablet with an intuitive interface, enabling direct local control of the system and its status. Use the tablet or a desktop computer for system setup, maintenance, troubleshooting, and routine monitoring. The tablet interface is available in 11 different languages to customize your user experience. Additionally, the tablet enables you to:

  • Communicate with the instrument via secured WiFi or a wired connection
  • Control and monitor one instrument at a time, with easy instrument switching
  • Access consumable installation guides and troubleshooting knowledge base
Dionex ICS-6000 HPIC system

The Dionex ICS-6000 HPIC system is available in a variety of configurations, including:

  • Standard Bore – Uses traditional ion chromatography column diameters, about 4mm, and flow rates, at around 1 ml/min. Standard bore scale IC covers most ion chromatography applications.
  • Microbore – Microbore scale IC reduces eluent consumption as well as waste generated by using 2 mm diameter columns and consumables. Flow rates average between 0.2 to 0.5 mL/min. Microbore IC also scales down required injection volumes and can provide some sensitivity gains.
  • Capillary - Capillary IC scales down column size, injection volumes, and flow rates by a factor of 10 to 100. Since flow rates are very low, For a 0.4 mm ID column, it would be about 10 µL/min, the system is easily operated 24 /7. This means less frequent calibration, and thus less operator intervention. Capillary IC consumes only 15 mL of water a day, translating into 5.25 L a year of eluent usage.
Format Capillary Microbore Standard
Typical flow rate range 5-20 µL/min 0.2-0.5 mL/min 1-2 mL/min
Column i.d. supported 0.2-0.6 mm 1-3 mm 3-7 mm
Typical yearly eluent usage 5.25 L 131 L 525 L

Multiple, flexible detector options

The Dionex ICS-6000 HPIC system supports a variety of detectors, including:

  • Suppressed conductivity
  • Electrochemical, including DC amperometry and integrated amperometry
  • UV-Vis absorbance, including variable wavelength and photodiode array
  • Inductively coupled plasma mass spectrometry (ICP-MS)
  • Mass spectrometry (MS)

Discover ion chromatography-mass spectrometry

The Dionex ICS-6000 HPIC system is compatible with single quadrupole, triple quadrupole, and high-resolution accurate-mass (HRAM) Thermo Scientific Orbitrap mass analyzer-based mass spectrometers for performing powerful ion chromatography-mass spectrometry (IC-MS) analyses.

Solve complex analysis challenges

The Dionex ICS-6000 HPIC system can address the full range of IC analysis applications. It is suitable for techniques from 2-D ion chromatography for trace-level analysis to high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) for complex carbohydrate analyses.

Which Dionex ICS-6000 HPIC system configuration is best for you?

 

Dionex ICS-6000 Standard Bore and Microbore HPIC Systems

Dionex ICS-6000 Capillary HPIC Systems

Dionex ICS-6000 Hybrid HPIC System

Major benefit

  Request quote Request quote Request quote  
Column configurations Two standard bore 4 mm, two microbore 2 mm, or one of each column Two capillary 0.4 mm columns One standard bore and one capillary, or one microbore and one capillary column Can run two different analyses simultaneously
Column compartment Dionex ICS-6000 DC Detector/Chromatography Compartment Dionex ICS-6000 Capillary IC Cube Dionex ICS-6000 Capillary IC Cube Allows easy column installation and connections
Column choices Offers broad variety of quality columns
Detectors (standard) Can be used in most common IC applications
Detectors (optional) Allows addition of detector for special applications
6000 psi pumps Can perform high pressure IC or, with dual pumps, 2D-IC
Eluent generator Capillary EG lasts 18 months; uses 5.25L water/day
Autosampler compatibility Offers a variety of cost and application options
CDS software Provides, power, simplicity and convenience

Ion Chromatography Mass Spectrometry (IC-MS)

Increase the power of IC with MS detection

Utilize mass detection when you need to ensure analytical confidence and dramatically improve the detection capability of your Thermo Scientific Dionex Integrion or ICS-6000 HPIC system. Ion chromatography with mass spectrometry (IC-MS) maximizes the ability to detect and quantify unexpected co-elutions of components and to confirm trace components.

  • Obtain higher sensitivity – MS detection is more sensitive than traditional IC detection techniques like conductivity and amperometry.
  • Get very accurate quantification – Mass spec gives excellent quantitation with a wide linear dynamic range
  • Have more confidence in your results - Peak identity and purity confirmation is very easy with mass spectrometry because you can focus your detection on selected masses.
  • Unmatched screening capabilities – Mass spec not only has sensitivity advantages but can find compounds in complex matrixies, in some cases, even when you are not looking for them.

Single Quadrupole IC-MS

Easily master MS for your IC applications

Triple Quadrupole IC-MS

Need sensitive, fast, and robust quantitation of a variety of molecule types? For complex samples, the high sensitivity and selectivity of MS/MS using selected reaction monitoring (SRM) provides the most precise and accurate quantitation using IC-MS.

Increase productivity, with reliability and robustness, for labs focused on performing targeted quantitation with the Thermo Scientific TSQ Fortis Triple Quadrupole Mass Spectrometer. This system makes it easier to meet today's demands by confidently answering more complex questions per sample, while achieving reproducible results.

Orbitrap IC-MS

Thermo Scientific Orbitrap mass spectrometers generate high-resolution and accurate-mass data, thereby enhancing sensitivity in trace analyte detection, characterization, and quantitation. That's why they are used in research applications—in particular, life science applications such as metabolomics.

Get a superior combination of scan speed, high resolution, mass accuracy, spectral quality and sensitivity for untargeted or targeted screening and a broad range of qualitative and quantitative applications in environmental, food safety and metabolomics.

Use this system for IC-MS in life science metabolomics research to analyze the most challenging low-abundance, high-complexity samples, to identify more compounds faster, quantify more accurately, and to elucidate structures more thoroughly.

Which mass spectrometer do I choose?

Mass Spectrometer Analyzer Mode of Operation MS MS/MS Sensitivity Peak Confirmation Structural Elucidation
ISQ EC MS Quadrupole Single ion monitoring (SIM)
TSQ Altis MS Triple Quadrupole Selected reaction monitoring (SRM)
TSQ Quantis MS Triple Quadrupole Selected reaction monitoring (SRM)
Q Exactive MS Orbitrap mass analyzer High Resolution Accurate Mass (HRAM)
Orbitrap Fusion MS Orbitrap mass analyzer High Resolution Accurate Mass (HRAM)
  = Not applicable   = Poor   = Good   = Better   = Best

Reduce the time and labor for determination of corrosive halogens and sulfur in difficult samples by using the Thermo Scientific Combustion Ion Chromatography (CIC) system. This combustion IC system eliminates complex sample preparation steps using an automated method that is highly sensitive, easy-to-use, saves time, and produces fewer environmental contaminants than other sample preparation procedures. Use the CIC system for applications such as the analysis of corrosive halogen, sulfur determination, and halide speciation.

  • Save time and labor – The system is fully automated which allows more time to be spent on other tasks.
  • Improved reproducibility – Automation improves analytical performance
  • Increased lab safety - Pyrohydrolysis eliminates the need to dispose of hazardous chemicals used in acid digestions or back extractions.
Combustion Ion Chromatography System

Major applications

  • Per and Poly-Fluoroalkyl substances PFAS
  • Sulfur, Chloride, Fluoride, and Bromine in plastics
  • Chloride, Fluoride, Bromine in pharmaceutical raw materials and finished ingredients
  • Chloride in epoxy resins
  • Chloride, Fluoride, and Sulfur in liquid petroleum gas
  • Bromine in disposable (one-time use) polymers
  • Chloride in lubricating oil
  • Fluorine, Bromine, and Iodine in soil samples
  • Fluorine in ores
  • Chloride and Fluorine in aluminum powder
  • Chloride and Sulfur in coal

Disc-IC — fully automated high throughput solution for water analysis

Unique and fully automated DISC-IC combines the power of direct measurement, discrete analysis, and ion chromatography to support comprehensive water analysis workflow. Disc-IC offers a complete solution for wet chemical and ion analysis needs offering a highest flexibility, sample throughput options that reduces overall cost per analysis. For growing laboratories that perform routine analysis while experiencing increased demand for routine wet chemical analysis, Thermo Scientific Gallery discrete analyzers automates labor-intensive and time-consuming wet chemical tests. Thermo Scientific Dionex Ion Chromatography (IC) systems automates the anions and cations analysis.

Disc-IC provide true walk-away solution for comprehensive ground water, process water and waste water analysis and performs unattended large sample series analysis.

Gallery or Gallery Plus with ECM Module
Gallery or Gallery Plus with ECM Module
ICS 6000 or Integrion or ICS 4000
ICS 6000 or Integrion or ICS 4000
Direct measurement: pH, Conductivity

Titration Parameters: Alkalinity, Total Hardness
Fast Anions: Fluoride, Chloride, Nitrite, Nitrate, Bromide, Phosphate and Sulfate

Standard anions and oxyhalide analysis
Advanced Wet Chemistry Parameters: Silica, Total phosphate, TKN, TON, Urea, Total Phenol, Total Cyanide, Sulfide, Hexavalent chromium, total iron, Zinc, Boron and organic acids Standard Cations: Lithium, Sodium, Ammonium, Potassium, Calcium and Magnesium

Standard cations and amines analysis

Which ion chromatography system is right for my laboratory?

It depends. Are you running routine analyses, or do you need advanced functions? You can choose from basic workhorses to high-pressure systems with electrolytic eluent generation. What’s the difference and how do they compare? Use the table below to see which one is right for you.

8
  Dionex Easion IC System Dionex Aquion IC System Dionex Integrion HPIC System Dionex ICS-4000 Capillary HPIC System Dionex ICS-6000 HPIC System
  Dionex Easion IC System Dionex Aquion IC System Dionex Integrion HPIC System Dionex ICS-4000 Capillary HPIC System Dionex ICS-6000 HPIC System
  Request quote Request quote Request quote Request quote Request quote
Advantages Kits for common anions or cations Simple analysis with increased precision Routine analyses Always ready, routine analyses Routine and complex analyses
Easily track suppressor performance using single-device suppression
Single-vendor software that controls multiple vendor instruments
Built-in method development software tool to efficiently optimize column and separation conditions
Automated, comprehensive consumables tracking reduces installation & tracking errors
Reusable, ultralow-dead-volume, high-pressure finger-tight connections that are easy to use
Accurate, reproducible electrolytic high-pressure gradients with shorter run times
Precise, accurate electrolytic eluent generation for excellent method reproducibility
Integrated detector options that protect your investment
Capillary IC system with the advantages of always-ready operation
Multiple pump configurations for your application flexibility
Runs 2D-IC applications for trace analyses
Mechanical and RFIC gradients to expand your capabilities
Increase productivity using single and dual configurations
Broad flow-rate options for capillary, microbore, and standard bore columns
Easy methods development using dual column temperature zones
Reconfigure with individual, stand-alone modules for special application requirements

IC and RFIC systems


Ion Chromatography Systems

Innovative ion chromatography systems for every performance and price requirement

Your ion chromatography (IC) system should meet the demands of your analyses, while still fitting within your budget. Whether you need a robust IC system for routine analysis or a flexible, modular system for more demanding analyses, we have what you need. Our IC systems include low-cost, high-pressure, capillary, and modular options for every analysis requirement.

Browse our complete portfolio below, or let one of our experts help you tailor a selection specific to your application and workflow needs.

Modular IC Systems

For more demanding IC applications, choose from these high-performing, high-pressure, highly configurable Thermo Scientific Dionex ICS-6000 HPIC systems.

Integrated IC Systems
Integrated ion chromatography systems

These integrated IC systems are complete, plug-and-play hardware solutions for your routine ion analyses. Select from basic economical workhorses, systems with electrolytic Reagent-Free Ion Chromatography (RFIC) capabilities, capillary high pressure systems, and more.

Specialty Ion Chromatography Systems
Combustion ion chromatography systems

We’ve integrated Dionex IC systems for specialty applications including titration and combustion.

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