Dionex ICS-6000 HPIC System: Run different methods simultaneously

The modular Thermo Scientific Dionex ICS-6000 HPIC system is a highly configurable ion chromatography (IC) system with high pressure capabilities. It enables you to develop and run different methods for a single sample or for different samples simultaneously. The robust design of this system enables operation at up to 5000 psi and produces consistent, reliable results. As a top-of-the-line ion chromatography system, the Dionex ICS-6000 HPIC system is designed to adapt to the needs of users and push the boundaries of what is possible in ion analysis.

Build your ideal Dionex ICS-6000 HPIC system


Flexible configurations

Dionex ICS-6000 HPIC systems come in a variety of configurations, with the ability operate as a single- or dual-channel system to run samples concurrently. This high-pressure IC system can address a full range of IC applications, from 2-D IC for trace-level analysis to high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) for complex carbohydrate analysis.

Versatile detection capabilities

The system is compatible with a wide variety of detectors, including suppressed conductivity, electrochemical, UV-Vis absorbance, inductively coupled plasma mass spectrometry (ICP-MS), and mass spectrometry (MS).

Wide range of IC columns

The Dionex ICS-6000 HPIC system is compatible with 4 μm-particle-size IC columns, which are available in 150 or 250 mm lengths. The 150 mm-length columns decrease run times while maintaining chromatographic resolution. The 250 mm-length columns offer improved peak resolution.

Mass spectrometry compatible

The Dionex ICS-6000 HPIC system is the ideal IC system to work in tandem with mass spectrometry, as it can used for a wide variety of sample analyses. From single quadrupole to high resolution accurate mass (HRAM) Thermo Scientific Orbitrap mass spectrometers, IC-MS analysis provides improved selectivity and higher sensitivity.

Automated Eluent Generation (EG)

For unmatched method reproducibility and accuracy, the system can electrolytically generate high-purity hydroxide, carbonate, bicarbonate, or methanesulfonic acid (MSA) eluents when provided with a source of high-purity deionized water. Using the Dual EGC mode, the Dionex ICS-6000 HPIC system can also generate potassium hydroxide/potassium methanesulfonate (KOH/KMSA) eluents for complex carbohydrate analysis.

CDS Software

The Dionex ICS-6000 HPIC system comes with the easy-to-use Thermo Scientific Chromeleon Chromatography Data System (CDS). This software provides powerful control and data processing for IC and offers eWorkflows that make all our essential applications easily accessible. Additionally, the Chromeleon CDS can control mass spectrometry systems, enabling seamless IC-MS analyses.


System specifications

The table below provides a brief overview of the Dionex ICS-6000 HPIC system specifications. Not all specifications are listed. For a full list of the specifications, download the Dionex ICS-6000 HPIC system specifications sheet.


Dionex ICS-6000 HPIC System



Dual-piston (in series), microprocessor controlled, constant 10 mm primary stroke length, variable speed Isokinetic Eluent Precompression


Chemically inert, metal-free PEEK pump heads and flow path; compatible with aqueous eluents of pH 0–14 and reversed-phase solvents

Pressure range

Analytical: 0–35 MPa (0–5000 psi)

Flow rate range

Analytical: 0.000–10.000 mL/min with settable flow increments at 0.001 mL/min, without changing pump heads. Optional heads allow flow up to 22.4 mL/min.

Flow rate precision

< 0.1%

Flow accuracy

< 0.1%

Pressure ripple

< 1% at 1.0 mL/min/typical, < 0.2% (with damper) at 10 µL/min, < 1.0% (without damper) typical


None required

Piston seal wash

Standard, automatic operation

Vacuum degasser

Integrated, optional 1 channel for isocratic pump or 4 channels for quaternary pump

Gradient formation

Quaternary low pressure (analytical only) or electrolytic eluent generation at high pressure

RFIC-EG gradients

Analytical: 0.1–100 mM

Gradient profiles

Any combination of an unlimited number of linear, convex, and concave positive and negative gradient profiles

Gradient proportioning accuracy and precision

±0.5 at 2 mL/min

Gradient mixing

Passive mixers for 2 mm and 4 mm i.d. columns, optional

Eluent generation

Optional eluent generation (RFIC-EG)

Eluent on/off valve

Electrically actuated, standard

Leak sensor

Optical, standard

System software


Chromeleon 7.2 CDS software, supports Microsoft® Windows® 7, operating systems

Automated procedure wizards

Standard feature

System smart startup and shutdown

Standard feature

Application templates

Standard feature

Automation support of 3rd party instruments

Fully controls over 300 different instruments from more than 30 manufacturers, including GC, HPLC, and MS

Customizable system control panels

Standard feature

Signal channels

Pump pressure

Data trending plots

All numerical device parameters

System status virtual channels

Standard feature

Power failure protection

Standard feature

System trigger commands and conditionals

Standard feature

Daily audit trail

Standard feature

Sample audit trail

Standard feature

System calibration storage

Factory, present and previous. Completely user selectable

Customized reporting

Standard feature with unlimited report sheets

GLP compliance


Physical specifications

Dimensions (h × w × d)

41 × 23 × 56 cm (16 × 8.75 × 21.5 in.)


SP: 20.4 kg (45 lb) — DP: 24.1 (55 lb)

Power requirements

90–265 V ac, 47–63 Hz

Flow path

All polymeric (PEEK), anion or cation configuration

For Research Use Only. Not for use in diagnostic procedures.