Dionex Integrion HPIC System: An easy solution for routine analysis

Achieve versatile and efficient separations that meet your routine ion analysis demands with the reliable Thermo Scientific Dionex Integrion HPIC system. Its high-pressure ion chromatography (HPIC) capabilities enable faster analysis without compromising data quality. The Dionex Integrion HPIC system is available in two models and a wide range of configurations. It is designed for routine ion chromatography (IC) applications for water, food and beverage, biofuels and pharmaceutical analysis.


Simple plumbing layout

The plumbing layout of this high-pressure ion chromatography system is based on a logical flow path for easy component access in a compact platform with a small physical footprint.

Automated Eluent Generation (EG)

Optional Reagent-Free Ion Chromatography with Eluent Generation (RFIC-EG) combines automated eluent generators and electrolytically regenerated suppressors to create eluents and regenerants.

Inert, reliable components
Inert, nonmetallic PEEK components throughout the Dionex Integrion HPIC system ensure compatibility with corrosive eluents and analyses free from metal contamination. Easy-to-install IC PEEK Viper fittings have low dead volume and require no special training or tools.

Consumables Device Monitor*

The Consumables Device Monitor automatically identifies consumables and maintains a record of their installation, use, and performance metrics on the Dionex Integrion HPIC system, eliminating the necessity for manual consumables tracking.

Wide range of IC columns

The Dionex Integrion HPIC system is compatible with a wide variety of column sizes, including smaller-particle-size 4 µm columns for HPIC capabilities, which provide faster run times and better resolution, to meet the requirements of your applications.  

CDS Software

The Dionex Integrion HPIC system comes with the easy-to-use Thermo Scientific Chromeleon Chromatography Data System (CDS). This software platform provides powerful control and data processing for IC and offers eWorkflows that make all our essential applications easily accessible.

*The wireless transmitter devices may not be authorized as required by the laws of your country, and these features will not be offered for sale or lease, or sold or leased, until proper authorization is obtained. Please consult your local sales representative for details.


System specifications

The table below provides an overview of the Dionex Integrion HPIC system specifications. Not all specifications are listed. For a full list of the specifications, download the Dionex Integrion HPIC system specifications sheet.


Dionex Integrion HPIC System



Dual-piston (in series), microprocessor controlled, constant 10 mm primary stroke length, variable speed isokinetic with eluent precompression


Chemically inert, metal-free PEEK pump heads and flow path; compatible with aqueous eluents of pH 0–14 and reversed-phase solvents

Pressure range

0–41 MPa (0–6000 psi)

Flow rate range

0.000–10.000 mL/min with ability to set flow increments at 0.001 mL/min

Flow precision

< ±0.1%

Flow accuracy

< ±0.1%

Pressure ripple

< 1% at 1.0 mL/min, typical

Eluent on-off valve

Electrically actuated, standard

Piston seal wash

Optional, automatic operation

Vacuum Degas

Integrated, optional

Eluent generator

Eluent types

Up to two eluent generator cartridges
KOH, LiOH, NaOH; Carbonate; Carbonate/Bicarbonate; MSA

Eluent concentration range

0.1–100 mM

Flow rates

0.1–3 mL/min
1.0 mL/min eluent concentration is limited

Maximum operating pressure

Dionex EGC 500 cartridge: 35 MPa (5000 psi)

Maximum solvent concentration

Cations: 0%
Anions (hydroxide): 25% methanol (KOH, NaOH and LiOH cartridges); Anions (carbonate/bicarbonate): None

Gradient profiles

Standard - any combination of linear, convex and concave positive and negative gradient profiles

Column compartment

Injection valves

Up to two high-pressure valves, either 6- or 10-port

Columns supported

Up to two 1-9 mm i.d., maximum length 250 mm analytical column with 50 mm guard column

Constant temperature zone

Temp. Range: 30 to 80 °C (86 to 176 °F); minimum 5 °C above ambient
Temperature Accuracy: ±0.5 °C at 30 °C)
Temperature Stability: ±0.2 °C (at 30 °C)
Time to Equilibration (ambient to ambient plus 20 °C): 20 minutes

Detector compartment

Constant temperature zone

Temp. Range: 15 (or 20 °C below ambient) to 40 °C (59 to 104 °F) Temperature Accuracy: ±0.5 °C (at 15 °C)
Temperature Stability: ±0.2 °C (at 15 °C)
Time to Equilibration (ambient to ambient minus 20°C): 30 minutes

Suppression modes

Chemical suppression

2 mm and 4 mm, anion and cation, membrane suppression

Electrolytic suppression recycle mode

2 mm and 4 mm, anion and cation, membrane suppression

Electrolytic suppression external water mode

2 mm and 4 mm, anion and cation, membrane suppression

Non-suppressed conductivity

Supported - both anion and cation

Conductivity detector

Electronics type

Microprocessor controlled digital signal processing, autoranging

Cell drive

8 kHz square wave




0.00238 nS/cm

Output range

Digital Signal Range: 0–15,000 µS/cm
Analog Signal Range: 0–15,000 µS/cm

Noise, wet

≤ 0.2 nS at 23 µS/cm background
≤ 0.1 nS at 1 µS/cm background


Rise times 0 to 10 s, programmable

Sampling rate

1 to 100 Hz, user settable or automatic

Cell temperature

7 °C above ambient to 60 °C maximum

Cell temperature stability

< 0.001 °C

Cell temperature compensation

Default 1.7% per °C; programmable from 0–3% per °C

Flow cell maximum pressure

10 MPa (1500 psi)

Flow cell volume

0.7 µL

Cell electrodes

Passivated 316 stainless steel. Compatible with MSA

Cell body

Chemically inert polymeric material

Heat exchanger

Inert, tortuous path for low longitudinal dispersion

Electrochemical detector

Electronics type

Microprocessor controlled digital signal processing

Electronic noise, wet

IPAD (Au electrode) < 50 pC at 10 mM KOH, DC Amperometry (GC) < 10 pA

Potential range

-2.0 to 2.0 V in 0.001 V increments

Signal range (digital and analog)

Integrated Amperometry: 50 pC to 200 µC DC Amperometry: 5 pA to 74 µA


0–10 s response time, user settable

Control mode

Local or remote control using relay closures or TTL, or control using Chromeleon CDS software via DC module

Cell body

Titanium body. Compatible with 2–7 mm i.d. columns

Working electrodes

Conventional: gold, glassy carbon, platinum, and silver Disposable: gold, platinum, carbon, and silver

Reference electrode

pH-Ag/AgCl combination, one piece design
PdH, one piece design



Analog output

User selectable full scale of 10, 100, or 1000 mV

Cell volume at working electrode

< 0.2 µL

Maximize cell operating pressure

0.7 MPa (100 psi)

Internal power supplies

Internal power supplies

Constant current (CC) power supplies

Option 1: 1 channel CC [0 - 500 mA]
Option 2: 2 channels CC [0 - 500 mA]
Option 3: 1 channel CC [0 - 500 mA] & 2 channels CC [0 - 500 mA]
Option 4: 1 channel CC [0 - 500 mA] & 4 channels CC [0 - 500 mA]

System software


Chromeleon CDS software, version 7.2 or higher

Automated workflow wizards

Standard feature

System smart startup and shutdown

Standard feature

Automation support of 3rd party instruments

Fully controls over 400 different instruments from more than 30 manufacturers, including GC, HPLC, and MS

Customizable system control panels

Standard feature

Signal channels

Detector signals and pump pressure as standard

Data trending plots

All numerical device parameters

System status virtual channels

Standard feature

Network failure protection

Standard feature for networked installations

System trigger commands and conditionals

Standard feature

Daily audit trail

Standard feature

Sample audit trail

Standard feature

System calibration storage

Factory, present and previous. Completely user selectable

Customized reporting

Standard feature with unlimited report sheets

GLP compliance


Physical specifications

Dimensions (h × w × d)

62.5 × 30.0 × 55.9 cm (24.6 × 11.8 × 22 in)


41 kg (90 lb)

Power requirements

100–240 V ac, 50-60 Hz autoranging

Operating temperature

4–40 °C (40–104 °F); cold-room compatible (4 °C) as long as system power remains on

Operating humidity range

5–95% relative, noncondensing

Control modes

Full control through front panel and Chromeleon CDS software; alternative control through TTL or relay closures; two relay outputs, two TTL outputs, four programmable inputs

USB communication protocol

One USB input; one built-in two-output USB hub

Leak detection

Built-in, optical sensor

For Research Use Only. Not for use in diagnostic procedures.