Liquid Chromatography

Quality, innovation and choice

Excellence in our liquid chromatography (LC) offering starts with an extensive line of HPLC columns, broad choice of modern and innovatively designed systems and their seamless connection to Thermo Scientific™ LC-MS systems. Our virtually zero-dead-volume Viper™ Fingertight Fittings are a leak-free at up to 1500 bar / 22,000 psi and amazingly easy-to-use solution to LC connections. The popular Chromeleon™ Chromatography Data System (CDS) software provides a complete solution with operation and data management of both your chromatography and mass spectrometry systems.

Popular liquid chromatography products
Vanquish™ Flex Binary UHPLC System
MAbPac™ RP LC Columns
Vanquish™ Flex Quaternary UHPLC System
Featured liquid chromatography categories

Get better resolution and sensitivity with faster analysis and consistent performance. Choose from reversed phase, HILIC, ion exchange, mixed mode, size exclusion, ligand exchange, application specific and more.

Characterize the full diversity of biomolecules. These column chemistries are specifically designed to separate proteins, peptides, monoclonal antibodies, carbohydrates, nucleic acids, and more.

Discover the next-generation Vanquish™ UHPLC systems, our proven UltiMate™ 3000 product line, and the EASY-nLC™ system.

Use our HPLC/UHPLC systems to connect with our MS systems to confidently identify, deeply characterize and precisely quantify a vast range of compounds.

Whether you have a single instrument, many from one or multiple manufacturers, or need an enterprise-wide solution, our CDS software is a great solution for chromatography and MS laboratories.

These virtually zero-dead-volume fittings provide leak-free connections and are extremely easy to use. Now you can quickly connect LC modules, valves and columns with ease, especially for HPLC, UHPLC and nano LC applications.

Combine maximum injection precision with huge sample capacity and high throughput capabilities. These autosamplers are optimized for highest ruggedness and uptime to ensure reliable nL to mL injections at any time.

Temperature rules retention, selectivity, and efficiency in chromatography. These column compartments allow for accurate and precise thermostatting and perfect alignment of eluent and column temperature to optimize your separation.

Retention time precision is the key to highest data confidence in peak identification and quantification. Our industry-leading pumps provide excellent flow accuracy and precision from nano LC to standard and UHPLC applications, and up to semi-preparative flow rates.

See the most in your sample. Choose from different flavors of detectors like diode array, multiple wavelength, variable wavelength, fluorescence, refractive index, electrochemical and charged aerosol detectors. Or add the pH and conductivity monitor to your system.

Get quality replacement parts and accessories specifically designed for your Thermo Scientific™ LC systems and columns.

Find your derivatization and visualization reagents, standards and reagents for amino acid and peptide applications, and ultrapure solvents for high-sensitivity analysis.


LC Columns and Consumables Catalog

Access the latest version of our Chromatography Columns and Consumables Catalog to ensure that you're optimizing your applications! Our enhanced online version features a robust applications search tool, access to method development guides, application notebooks, and much more.

Download catalog ›