Fast separations, high resolution, freedom of choice

Fast separations, high resolution, freedom of choice

Perform the full range of rapid HPLC and UHPLC applications on one system. Thermo Scientific™ UltiMate™ 3000 Rapid Separation systems combine unique hardware features and the ability to use small particle columns for fast separations with excellent resolution. All system components are coordinated for high performance. Available in biocompatible and non-biocompatible setups and featuring unique technological innovations like dual-gradient capabilities, the UltiMate 3000 RS systems sustain even most advanced workflows.

Featured rapid separation system products
Acclaim™ 120 C18 Columns
Viper™ Fingertight Fittings
Chromeleon 7.2 CDS Software

Rapid separation HPLC systems

Rapid Separation (RS) Systems
Rapid Separation (RS) Systems

Providing ultra-fast separations with ultra-high resolution in an exceptionally versatile HPLC/UHPLC system for the rigorous demands of large and small molecule analysis, these systems operate at pressures up to 1000 bar.

UltiMate™ 3000 Rapid Separation Binary System Get fast, high resolution separations with maximum flow rate flexibility. A fast gradient response and excellent flow rate stability ensure reliable results.
UltiMate™ 3000 Rapid Separation Quaternary System This is the most flexible RS system for established and novel HPLC and UHPLC workflows. The quaternary system supports fast routine applications and method development.
UltiMate™ 3000 Rapid Separation Dual System Increase productivity with this dual rapid separation system featuring online-SPE, parallel or tandem HPLC/UHPLC, inverse gradients and fast application switching.
Biocompatible Rapid Separation (BioRS) Systems

Get UHPLC performance for proteins, peptides, nucleic acids, and biotherapeutics. These systems are 100% corrosion free for use with high salt or extreme pH conditions. They operate with column pressures up to 1000 bar.

UltiMate™ 3000 BioRS System Protect your large molecules from unwanted degradation and modification. This UHPLC handles your needs from discovery to target isolation and purification.
UltiMate™ 3000 BioRS Dual System Accelerate your Bio-UHPLC analyses. This dual system automates multiple UHPLC separations to combine non-compatible chemistries in one workflow.
Biocompatible Rapid Separation (BioRS) Systems
Featured UltiMate 3000 BioRS system video
Quick overview of the UltiMate 3000 BioRS system

The UltiMate 3000 BioRS is designed to combine the performance advantages of ultra-high-performance liquid chromatography (UHPLC) with the corrosion-resistant flow path needed to analyze proteins, peptides, nucleic acids and biotherapeutics. The system was designed to accelerate research into promising biotherapies, such as monoclonal antibody variants.


Featured on-demand HPLC webinars
Featured on-demand webinars
Are you using the right LC column?

Access the latest version of our Chromatography Columns and Consumables Catalog in PDF and online formats. The enhanced online version features a robust applications search tool, access to method development guides, application notebooks, and much more.

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