Four workflows. Two flow paths. One integrated UHPLC solution.
Improve your productivity and sample knowledge for a faster return on investment with the Thermo Scientific Vanquish Duo UHPLC systems. The Vanquish Duo UHPLC systems expand the benefits of our award-winning Vanquish platform with four workflows (Dual LC, Tandem LC or LC-MS, Transcend Duo LX-2, and Inverse Gradient). Vanquish Duo UHPLC systems use a separate second flow path in one integrated system. Save time and cost per sample without adding bench space, and without compromising performance, robustness, or ease-of-use.
Boost productivity without sacrifice
As a member of the Vanquish UHPLC product line, the Vanquish Duo UHPLC systems share all Vanquish-inherent values, such as a design focus on uptime, robustness and reliability.
- The Thermo Scientific Vanquish Dual Split Sampler and Thermo Scientific Dual Pump extends the flexibility of the Vanquish UHPLC product line, ensuring the highest productivity and fastest return on investment in a single instrument bench space.
- Multiple detection options designed for Vanquish gives you the freedom to choose for optimum data and the performance you need.
- Thermo Scientific Viper Fingertight Fitting connections throughout the system make set up easy.
Also benefit from the industry-leading, easy-to-use, and compliant-ready Thermo Scientific Chromeleon Chromatography Data System (CDS) with eWorkflow method setup, dedicated ePanels, Open Access, and smart tools. Chromeleon CDS delivers advanced system communication with single-point intelligent control and functionality. It also provides direct plugins for the Vanquish Duo UHPLC systems to other manufacturers' chromatography data systems.
Choose from Four Vanquish Duo UHPLC systems
Vanquish Duo system for Dual LC
Double your throughput or deepen your sample knowledge. Run the same method on both flow paths or two different methods simultaneously on one instrument, improving your lab productivity, sample knowledge, bench space usage and overall return on investment.
Build a Vanquish Duo for Dual LC to fit your application needs.
- Improve return on investment by reducing cost per sample
- Increase sample throughput without changing validated methods
- Increase output without sacrificing bench space
- Analyze the same set of samples with multiple methods reducing sample preparation time and maximizing sample information
Vanquish Duo system for Tandem LC or LC-MS
Ready to improve your lab throughput and get the most out of your detector or mass spectrometer? The Vanquish Duo for Tandem LC or LC-MS system accomplishes this by performing your analysis on two pumps and two columns all in one system. Deliver the analytical gradient on the first pump while the second pump reconditions the column- preparing it for the next injection.
- Increase sample throughput without modifying a validated method
- Improve return on investment by maximizing the instrument utilization
- Reduce column carry over through extended column washing without sacrificing throughput
- Simplify method setup with automatic method conversion from your original gradient method
Double the throughput of your LC-MS application. Perform up to two applications simultaneously with a multi-channel LC while benefitting from the robustness, performance, and ease-of-use built into the Vanquish platform.
- Double the throughput of your LC-MS application without the need for additional bench space.
- Use the most intuitive multi-channel system ever built.
- Simplify method setup with intuitive Thermo Scientific Aria software, which is compatible with Thermo Scientific Xcalibur software and Thermo Scientific TraceFinder software.
- Improve return on investment through intelligent scheduling of instrument use.
Vanquish Duo system for Inverse Gradient
Improve your lab's quantification capabilities. This system employs the unique and universal charged aerosol detection to quantify any compound even when no reference standard is available. The instrument method setup can be easily done with smart Chromeleon CDS wizards without any extra effort.
- Uniform response with charged aerosol detection under gradient elution conditions
- Simplifying method setup with automatic Inverse Gradient calculation considering all system volumes
- Reliable standard free quantification of knowns and unknowns
Vanquish Duo system for Dual LC
Double your throughput or deepen your sample knowledge. Run the same method on both flow paths or two different methods simultaneously on one instrument, improving your lab productivity, sample knowledge, bench space usage and overall return on investment.
Build a Vanquish Duo for Dual LC to fit your application needs.
- Improve return on investment by reducing cost per sample
- Increase sample throughput without changing validated methods
- Increase output without sacrificing bench space
- Analyze the same set of samples with multiple methods reducing sample preparation time and maximizing sample information
Vanquish Duo system for Tandem LC or LC-MS
Ready to improve your lab throughput and get the most out of your detector or mass spectrometer? The Vanquish Duo for Tandem LC or LC-MS system accomplishes this by performing your analysis on two pumps and two columns all in one system. Deliver the analytical gradient on the first pump while the second pump reconditions the column- preparing it for the next injection.
- Increase sample throughput without modifying a validated method
- Improve return on investment by maximizing the instrument utilization
- Reduce column carry over through extended column washing without sacrificing throughput
- Simplify method setup with automatic method conversion from your original gradient method
Double the throughput of your LC-MS application. Perform up to two applications simultaneously with a multi-channel LC while benefitting from the robustness, performance, and ease-of-use built into the Vanquish platform.
- Double the throughput of your LC-MS application without the need for additional bench space.
- Use the most intuitive multi-channel system ever built.
- Simplify method setup with intuitive Thermo Scientific Aria software, which is compatible with Thermo Scientific Xcalibur software and Thermo Scientific TraceFinder software.
- Improve return on investment through intelligent scheduling of instrument use.
Vanquish Duo system for Inverse Gradient
Improve your lab's quantification capabilities. This system employs the unique and universal charged aerosol detection to quantify any compound even when no reference standard is available. The instrument method setup can be easily done with smart Chromeleon CDS wizards without any extra effort.
- Uniform response with charged aerosol detection under gradient elution conditions
- Simplifying method setup with automatic Inverse Gradient calculation considering all system volumes
- Reliable standard free quantification of knowns and unknowns
Overview of the Vanquish Duo Systems
| Vanquish Duo System for Dual LC | Vanquish Duo System for Tandem LC or LC-MS | Vanquish Duo System for Transcend Duo LX- 2 | Vanquish Duo System for Inverse Gradient | ||
|---|---|---|---|---|---|
| Workflow Benefits | Improved return on investment* * Calculate your savings |
Double throughput or increase sample knowledge |
Increased detector utilization |
Maximum MS utilization |
Reliable quantification with CAD |
| Saves bench space | |||||
| Easy-to-use | |||||
| Run complementary assays | |||||
| Increased throughput for LC-MS | na |  |
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na | |
| Reliably quantify unknowns | |||||
| Dedicated workflow kits | Improved return on investment | Vanquish Duo for Dual LC Workflow Kit | Vanquish Duo for Tandem LC or LC-MS Workflow Kit |
Vanquish Duo for Transcend Duo LX-2 | Vanquish Duo for Inverse Gradient Workflow Kit |
| SmartInject technology for unsurpassed retention time precision | |||||
| SmartFlow technology for excellent flow precision | |||||
| Active and passive solvent pre-heating | |||||
| Multi-mode column thermostatting | |||||
| Sample cooling | Temperature range: 4 – 40 °C |
Temperature range: 4 – 40 °C |
Temperature range: 4 – 40 °C |
Temperature range: 4 – 40 °C |
|
| System Components | Pump | One: Vanquish Dual Pump F Or A combination of two individual Vanquish pumps: |
Either two Vanquish Binary Pump F or two Vanquish Binary Pump H |
One: Vanquish Dual Pump F Or A combination of two individual Vanquish pumps: |
|
| Sampler | Vanquish Dual Split Sampler FT For applications up to 1000 bar Or Vanquish Dual Split Sampler HT For applications up to 1500 bar |
Vanquish Split Sampler FT For applications up to 1000 bar Or Vanquish Split Sampler HT For applications up to 1500 bar |
Vanquish Dual Split Sampler FT For applications up to 1000 bar Or Vanquish Dual Split Sampler HT For applications up to 1500 bar |
Vanquish Split Sampler FT For applications up to 1000 bar Or Vanquish Split Sampler HT For applications up to 1500 bar |
|
| Extended Sample Capacity | Vanquish Charger (optional) An intelligent, robotic rack and plate feeder that automatically loads samples in the autosampler and extends the sample capacity of all Vanquish samplers to up to 8832 samples (23 wellplates or 12 vial racks) with innovative air-stream cooling and barcode reading for inventory management. |
Vanquish Charger (optional) An intelligent, robotic rack and plate feeder that automatically loads samples in the autosampler and extends the sample capacity of all Vanquish samplers to up to 8832 samples (23 wellplates or 12 vial racks) with innovative air-stream cooling and barcode reading for inventory management. |
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| Column compartment | 1 or 2 column compartments depending on application | 1 column compartment | 1 or 2 column compartments depending on application | 1 column compartment | |
| Vanquish Column Compartment Provides two column thermostatting modes (still and forced air), active and passive solvent pre-conditioning and post-column cooling for optimized control of your separations and advanced method transfer. |
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| Detectors | A combination of two detectors: | One mass spectrometer | Any detector(s): | Vanquish Charged Aerosol Detector (Optional second detector) |
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| Virtually zero dead volume system connections | Viper UHPLC Fittings Kits Order all the UHPLC fittings and capillaries you need for your system or application in a single kit |
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Compatible components for all Vanquish UHPLC systems
| Detector options | Vanquish columns | Chromeleon CDS |
|---|---|---|
Extend pressure capabilities and robustness by using columns that were developed for Vanquish systems, allowing you to separate your science better, faster, and easier than ever before.
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Discover the best HPLC systems for your applications and budget
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HPLC Systems Selection Guide
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LC Method Transfer Calculator
Use this online calculator to transfer methods from HPLC to UHPLC conditions. Calculate the new gradient table, adjust sample volumes and run times if applicable.
