Deliver results without compromise
Today’s scientists solve various challenges needed to produce life-saving medicines, improve the quality of our food and the environment, and discover the next breakthrough in science. Built from the ground up, the Thermo Scientific Vanquish Horizon UHPLC System is our premier UHPLC system to help solve these challenges. It delivers more and better results with superior separations and easier interaction with no trade-offs in performance, robustness, or ease-of-use. This fully integrated and biocompatible system features high sample capacity for high-throughput workflows, industry-leading pumping performance, amazingly high signal-to-noise (S/N) and linearity, two-mode thermostatting, and more.
Setting new standards in UHPLC
This integrated, fully biocompatible system provides you with unrivaled performance and throughput for applications requiring high-end UHPLC.
- Unsurpassed retention time and peak area precision
- Highest detector sensitivity and lower baseline noise
- Less maintenance and easy set-up with Thermo Scientific Viper Fingertight Fittings
- Dedicated solutions for exceptional LC-MS performance
Continuous, worry-free operation
Reliable and continuous worry-free operation of HPLC instruments is critical for analytical laboratories to achieve the highest productivity and dependable results.
The Thermo Scientific Vanquish Solvent Monitor delivers productivity improvements through the avoidance of unintended dry solvent channels and supports your laboratory's compliance efforts by automatically logging eluent changes. Additionally, monitoring of your waste container levels can ensure your laboratory's smooth operation by preventing hazardous spills.
Solvent and waste levels can be monitored directly on the instrument, through the Thermo Scientific Vanquish User Interface, or remotely with Thermo Scientific Chromeleon Chromatography Data System (CDS) software.
Also benefit from the industry-leading, easy-to-use and compliant Thermo Scientific Chromeleon Chromatography Data System (CDS) with eWorkflow method setup, dedicated ePanels, Open Access, and smart tools. Chromeleon CDS delivers advanced system communication with single-point intelligent control and functionality, and provides direct plugins for the Vanquish Horizon UHPLC system to other manufacturers' chromatography data systems.
Chromatography columns and consumables
Overview of the Vanquish Horizon UHPLC system
|Vanquish Horizon UHPLC System|
Up to 1500 bar
|Retention time precision|
0 – 5 mL/min
|SmartInject technology for unsurpassed retention time precision|
|SmartFlow technology for excellent flow precision|
|Pump||High-pressure gradient proportioning|
|Active and passive solvent pre-heating|
|Multi-mode column thermostatting|
Temperature range: 4 – 40 °C
|System components||Pump||Vanquish Binary Pump H
The pump with the highest backpressure at 1500 bar; ideal for any gradient performance, from shallow to ballistic
|Autosampler||Vanquish Split Sampler HT
Excellent precision, accuracy, and short cycle times with innovative air-stream cooling and barcode reading for inventory management for all workflows up to 1500 bar
|Extended sample capacity||Vanquish Charger (optional)
An intelligent, robotic rack and plate feeder that automatically loads samples in the autosampler and extends the sample capacity of all Vanquish samplers to up to 8832 samples (23 wellplates or 12 vial racks) with innovative air-stream cooling and barcode reading for inventory management.
|Column compartment||Vanquish Column Compartment
Provides two column thermostatting modes (still and forced air), active and passive solvent pre-conditioning and post-column cooling for optimized control of your separations and advanced method transfer.
|Virtually zero dead volume system connections||Viper UHPLC Fittings Kits
Order all the UHPLC fittings and capillaries you need for your system or application in a single kit
|= Not applicable||= Poor||= Good||= Better||= Best|
Compatible components for all Vanquish UHPLC systems
|Detector options||Vanquish columns||Chromeleon CDS|
|Extend pressure capabilities and robustness by using columns that were developed for Vanquish systems, allowing you to separate your science better, faster, and easier than ever before.
Discover the best HPLC systems for your applications and budget
Use these tools to help you decide
HPLC Systems Selection Guide
Use this tool to rank the top HPLC instruments for your applications based on your responses to simple pull-down menus.
HPLC System Total Cost of Ownership Calculator
Use this tool to estimate your cost for purchasing and running Thermo Scientific HPLC and UHPLC systems. You can compare costs between instruments.
LC Method Transfer Calculator
Use this online calculator to transfer methods from HPLC to UHPLC conditions. Calculate the new gradient table, adjust sample volumes and run times if applicable.
Rowan University shares the favorite features in the Thermo Scientific Vanquish UHPLC and Chromeleon CDS, along with how easy it was to train students to use the system.