Small, simple, and scalable
Achieve reliable scale-up, reduced time to market, and controlled, continuous processing using Thermo Scientific compounders and extruders. Our twin-screw compounders offer flexible compounding configurations for small batches for either pilot scale production or low volume manufacturing and are well-suited for research and development in the polymer, pharmaceutical, bioscience, and nanotechnology sectors. Pharmaceutical manufacturers rely on our twin-screw extruders to create uniform material blends for the preparation of various dosage forms for low solubility APIs. Our instruments cater to a broad range of process requirements for even the most challenging drug formulations.
Thermo Scientific pharmaceutical compounders for hot melt extrusion and continuous granulation offer reliable solutions for drug discovery and development. Our pharmaceutical extruders meet a wide range of drug development applications and are ideal for developing and testing recipes with expensive API and associated compounds.
Simplify your processing and QC procedures with Thermo Scientific scale-up extruders and compounders. We produce a versatile range of twin-screw extruders with customizable options to fit the demanding and evolving environments of research, development, production, and quality control for pharmaceutical, industrial, and polymer applications.
A torque rheometer is a measuring mixer or extruder system used in quality control (QC) and research and development (R&D) for materials such as polymers, rubber, ceramic mixtures or food. Torque rheometers deliver information about melting behavior, influence of additives on processability, temperature or shear stability, and rheological characterization, e.g., injection molding.
The advantage of modular torque rheometers is that an interchangeable mixer, single-screw extruder, or conical and parallel twin-screw extruder can be connected to maximize flexibility for daily measuring needs.
Micro-compounders are suitable for early material development when only a few grams of sample available for testing . For example, 5 grams is sufficient with a micro-compounder.
All micro-compounder models are equipped with a back-flow channel and a bypass valve which allow control of the residence time of the sample in the compounder. Depending on the compounder model, it is also possible to measure the relative sample viscosity at different screw speeds. When combined with a mini injection molding machine, scientists can produce specimens for further analysis from limited sample amounts.
We offer a broad range of up- and down-stream equipment to complete the compounding process. Accessories such as pelletizers, wire coating, blow-molding, film take off and chill rolls, as well as a range of dies and feeding systems are available.
See our Workshops and Seminars
Have a look at our upcoming workshops that are close to you.
Our workshops will refresh or enhance your molecular spectroscopy, surface analysis, material characterization or elemental analysis knowledge.
ODFs made easy with HME
Orally disintegrating films (ODFs) allow safe, easy and exact dosage of active pharmaceutical ingredients (APIs). They also improve bioavailability of the API and help avoid the first pass effect. Hot-melt extrusion (HME) works well for manufacturing ODFs; it’s well-established, provides reproducible results, and doesn’t require solvents. Produce high-quality ODFs at lab- or production-scale.
‘Green tires’ that you can actually make
There’s a lot of choice in tire ingredients – natural rubber vs synthetics, silica, carbon black types, reinforcing fibers, compounding agents, etc. Your next eco-friendly ‘green’ tire has to be one you can also manufacture on the production line.
By simulating a full-scale processing environment in the test lab with a modular torque rheometer and extruder system, you can test the processability of various rubber compounds. View this free application note showing how such a system was used to test rubber compound with different types of carbon black.