Orbitrap Tribrid LC-MS New Customer Center

Your customer experience is important to us

Explore the information below and discover the capabilities of your new instrument, or please contact us to speak with a specialist if there is something we can help you with.

Speak to a specialist


Mass spectrometry
rewards program

Get rewarded for your new Orbitrap Tribrid MS with savings up to 40% off select Thermo Scientific MS products.

Calibration solutions,
standards and solvents

Ready-to-use liquid formulations that can quickly calibrate Thermo Scientific LC-MS instrumentation.



Data analysis

Thermo Scientific Proteome Discoverer software simplifies a wide range of proteomics workflows and is recommended for quantitative analysis of TMT-based data. The software has improved data processing capabilities for handling large data sets and is enabled with study management tools.

Thermo Scientific Proteome Discoverer software
  • A new user interface for adding reporter ion isotopic distributions
  • Ability to account for reporter ion isotopic impurities for TMT10plex and TMT11plex reagents
  • Implementation of TMT quantification based on S/N values
  • Protein and peptide quantification based on the sum of S/N values
  • New methods for normalization and scaling for peptide and protein abundance values

A demo version of Proteome Discoverer software is available free of charge. 

Download a free 60-day trial

Monitor your mass spectrometry analyses anywhere, anytime.

Almanac web-based monitoring and management monitors your mass spectrometry analyses anywhere, anytime. Its web- and smartphone-based application gives you the ability to remotely access and manage your LC-MS systems, maximizing up time and freeing you to focus on other important tasks during your day. Check real-time system status and acquisitions, set up automated e-mails to notify you of a completed acquisition or error, schedule instrument access, monitor utilization, or send service files to aid in system diagnostics.

Learn more

Unless stated otherwise, Proteome Discoverer software would be recommended for each of the workflows below.
The below workflows are not relevant for the Thermo Scientific Orbitrap ID-X Tribrid Mass Spectrometer.

Thermo Scientific Pierce EasyPep Mini MS Sample Prep Kit

Prepare your samples in less than 3 hours using pre-formulated reagents for analysis by mass spectrometry.

Mass Spectrometry Sample Preparation Technical Handbook

This 84-page handbook provides helpful hints and troubleshooting for preparation of samples from a variety of sources for MS analysis.

Open handbook

TMT10plex Isobaric Label Reagent Set plus TMT11-131C Label Reagent

Amine-reactive Thermo Scientific TMT10plex Isobaric Mass Tag Labeling Reagent Set plus TMT11-131C increases sample multiplexing from 10-plex to 11-plex, enabling even greater throughput for protein identification and quantitative analysis by tandem mass spectrometry (MS).

Sample labeling for TMT-based quantitation

Protein extracts isolated from cells or tissues are reduced, alkylated and digested overnight. Samples are labeled with the TMT Reagents and then mixed before sample fractionation and clean-up. Labeled samples are analyzed by high resolution Orbitrap LC-MS/MS to identify peptides and quantify reporter ion relative abundance. See the
 User's Guide for a step-by-step TMT labeling procedure for intact proteins as well as peptides including preparing whole cell protein extracts, protein digestion, and peptide labeling.

Pierce High pH Reversed-Phase Peptide Fractionation Kit

Increase protein identification from LC/MS analysis through orthogonal peptide fractionation of complex peptide samples.

Free webinar: Sample prep reagents for improved proteome depth, quantification and throughput

Simplifying Complexity: New MS Reagents that Improve Proteome Depth, Quantification, and Throughput

This webinar focuses on an optimized proteomics sample preparation workflow for isobaric tags and highlights new tools for fractionation, sample throughput, accurate quantitation.

Trapping column

Thermo Scientific Acclaim PepMap 100 C18 LC column, 75 μm x 2 cm

Obtain high resolution separations of low abundant peptides in complex proteomic samples using the Acclaim PepMap 100 C18 columns with their high loading capacity.

Separator column

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization

Pierce TMT11plex Yeast Digest Standard

The Thermo Scientific Pierce TMT11plex Yeast Digest Standard is a lyophilized yeast peptide mixture of four congenic strains labeled with TMT11plex reagents to monitor LC-MS/MS system performance for Tandem Mass Tag (TMT) quantitation.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range in the Ultimate 3000 RSLCnano which gives you the flexibility you need for low flow applications.

Thermo Scientific Pierce EasyPep Mini MS Sample Prep Kit

Prepare your samples in less than 3 hours using pre-formulated reagents for analysis by mass spectrometry.

Mass Spectrometry Sample Preparation Technical Handbook

This 84-page handbook provides helpful hints and troubleshooting for preparation of samples from a variety of sources for MS analysis.

Open handbook

TMT10plex Isobaric Label Reagent Set plus TMT11-131C Label Reagent

Amine-reactive Thermo Scientific TMT10plex Isobaric Mass Tag Labeling Reagent Set plus TMT11-131C increases sample multiplexing from 10-plex to 11-plex, enabling even greater throughput for protein identification and quantitative analysis by tandem mass spectrometry (MS).

Sample labeling for TMT-based quantitation

Protein extracts isolated from cells or tissues are reduced, alkylated and digested overnight. Samples are labeled with the TMT Reagents and then mixed before sample fractionation and clean-up. Labeled samples are analyzed by high resolution Orbitrap LC-MS/MS to identify peptides and quantify reporter ion relative abundance. See the
 User's Guide for a step-by-step TMT labeling procedure for intact proteins as well as peptides including preparing whole cell protein extracts, protein digestion, and peptide labeling.

Pierce High pH Reversed-Phase Peptide Fractionation Kit

Increase protein identification from LC/MS analysis through orthogonal peptide fractionation of complex peptide samples.

Free webinar: Sample prep reagents for improved proteome depth, quantification and throughput

Simplifying Complexity: New MS Reagents that Improve Proteome Depth, Quantification, and Throughput

This webinar focuses on an optimized proteomics sample preparation workflow for isobaric tags and highlights new tools for fractionation, sample throughput, accurate quantitation.

Trapping column

Thermo Scientific Acclaim PepMap 100 C18 LC column, 75 μm x 2 cm

Obtain high resolution separations of low abundant peptides in complex proteomic samples using the Acclaim PepMap 100 C18 columns with their high loading capacity.

Separator column

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization

Pierce TMT11plex Yeast Digest Standard

The Thermo Scientific Pierce TMT11plex Yeast Digest Standard is a lyophilized yeast peptide mixture of four congenic strains labeled with TMT11plex reagents to monitor LC-MS/MS system performance for Tandem Mass Tag (TMT) quantitation.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range in the Ultimate 3000 RSLCnano which gives you the flexibility you need for low flow applications.

Mass spec analysis of TMT labeled samples

What is synchronous precursor selection?

The SPS method begins with selection of the parent ion in the MS scan, followed by its isolation in the quadrupole and fragmentation by collisionally induced dissociation (CID) in the ion trap. Following fragmentation, SPS enables simultaneous isolation of up to 20 MS2 fragment ions. A select group of MS2 fragment ions are then transferred back into the ion routing multipole (IRM) where they undergo higher energy collisional dissociation (HCD) fragmentation, with the MS3 fragments then detected in the Orbitrap analyzer.

The use of SPS dramatically increases the reporter ion signal intensity and improves the ratio accuracy, due to improved counting statistics, leading to a significant increase in the number of quantified peptides.

Watch this free webinar to learn more

Robust classification of stem cell protein location by SPS-MS 3

Kathryn Lilley from University of Cambridge describes hyperLOPIT; a spatial proteomics method which enables the characterization of protein subcellular localization.

Synchronous Precursor Selection
 Click to enlarge

Technical resources

Technology

Phosphopeptide and TMT

Cancer proteomics

Other applications

Top

Thermo Scientific Pierce Trypsin/Lys-C protease mix, MS-Grade, is a mass spectrometry (MS)-grade serine endoproteinase mixture of trypsin and LysC that can be used for concurrent digestion of proteins for more efficient digestion than with trypsin alone.

High-Select TiO2 Phosphopeptide Enrichment Kit

The Thermo Scientific High-Select TiO2 Phosphopeptide Enrichment Kit enables efficient enrichment of phosphorylated peptides from complex and fractionated protein digests for analysis by mass spectrometry (MS). (This product replaces Cat. No. 88301.)

High-Select Fe-NTA Phosphopeptide Enrichment Kit

The Thermo Scientific High-Select Fe-NTA Phosphopeptide Enrichment Kit enables efficient enrichment of phosphorylated peptides from complex and fractionated protein digests for analysis by mass spectrometry (MS). (This product replaces Cat. No. 88300.)

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

Thermo Scientific Pierce Trypsin/Lys-C protease mix, MS-Grade, is a mass spectrometry (MS)-grade serine endoproteinase mixture of trypsin and LysC that can be used for concurrent digestion of proteins for more efficient digestion than with trypsin alone.

High-Select TiO2 Phosphopeptide Enrichment Kit

The Thermo Scientific High-Select TiO2 Phosphopeptide Enrichment Kit enables efficient enrichment of phosphorylated peptides from complex and fractionated protein digests for analysis by mass spectrometry (MS). (This product replaces Cat. No. 88301.)

High-Select Fe-NTA Phosphopeptide Enrichment Kit

The Thermo Scientific High-Select Fe-NTA Phosphopeptide Enrichment Kit enables efficient enrichment of phosphorylated peptides from complex and fractionated protein digests for analysis by mass spectrometry (MS). (This product replaces Cat. No. 88300.)

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

Top

After size-exclusion chromatography to separate the crosslinked complex, digest using MS grade proteolytic enzyme.

Thermo Scientific Pierce Trypsin Protease, MS Grade

Utilize this serine protease for its selectivity which enables reproducible protein digestion and mass-spectrometry based protein identification.

Thermo Scientific Pierce Lys-C Protease, MS-grade

Use this MS-grade serine protease in tandem with trypsin for enhanced digestion.

Peptide Enrichment and Fractionation for Mass Spectrometry

Increase protein identification by over 50% in complex peptide samples using orthogonal peptide fractionation.

Simplifying complexity: New MS reagents that improve proteome depth, quantification, and throughput

This webinar focuses on an optimized proteomics sample preparation workflow for isobaric tags and highlights new tools for fractionation, sample throughput, accurate quantitation.

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

After size-exclusion chromatography to separate the crosslinked complex, digest using MS grade proteolytic enzyme.

Thermo Scientific Pierce Trypsin Protease, MS Grade

Utilize this serine protease for its selectivity which enables reproducible protein digestion and mass-spectrometry based protein identification.

Thermo Scientific Pierce Lys-C Protease, MS-grade

Use this MS-grade serine protease in tandem with trypsin for enhanced digestion.

Peptide Enrichment and Fractionation for Mass Spectrometry

Increase protein identification by over 50% in complex peptide samples using orthogonal peptide fractionation.

Simplifying complexity: New MS reagents that improve proteome depth, quantification, and throughput

This webinar focuses on an optimized proteomics sample preparation workflow for isobaric tags and highlights new tools for fractionation, sample throughput, accurate quantitation.

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

Technical resources

General

Top

Protein and peptide identification

Thermo Scientific Pierce EasyPep Mini MS Sample Prep Kit

Prepare your samples in less than 3 hours using pre-formulated reagents for analysis by mass spectrometry.

Thermo Scientific Acclaim 75 μm x20 mm, PepMap100 C18, 3 μm

Separate low abundance peptides in complex samples using the Acclaim PepMap LC columns.

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

The Thermo Scientific Pierce Peptide Retention Time Calibration Mixture enables reversed phase liquid chromatography (LC) and mass spectrometry (LC-MS) users to optimize and confirm correct operation of their equipment.

Peptide retention time calibration mixture

The Thermo Scientific Pierce HeLa Protein Digest Standard is a highly validated mammalian protein digest that may be used as a quality control sample for mass spectrometry (MS) analysis of complex proteomic samples.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

Thermo Scientific Pierce EasyPep Mini MS Sample Prep Kit

Prepare your samples in less than 3 hours using pre-formulated reagents for analysis by mass spectrometry.

Thermo Scientific Acclaim 75 μm x20 mm, PepMap100 C18, 3 μm

Separate low abundance peptides in complex samples using the Acclaim PepMap LC columns.

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

The Thermo Scientific Pierce Peptide Retention Time Calibration Mixture enables reversed phase liquid chromatography (LC) and mass spectrometry (LC-MS) users to optimize and confirm correct operation of their equipment.

Peptide retention time calibration mixture

The Thermo Scientific Pierce HeLa Protein Digest Standard is a highly validated mammalian protein digest that may be used as a quality control sample for mass spectrometry (MS) analysis of complex proteomic samples.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

Top

Thermo Scientific Pierce EasyPep Mini MS Sample Prep Kit

Prepare your samples in less than 3 hours using pre-formulated reagents for analysis by mass spectrometry.

Thermo Scientific Acclaim 75 μm x20 mm, PepMap100 C18, 3 μm

Separate low abundance peptides in complex samples using the Acclaim PepMap LC columns.

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

 

<li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/posters/PN-64761-Recombinant-Proteins-ASMS2016-PN64761-EN.pdf" target="_blank">Poster Note: Development of Mass Spectrometry-Based Methods for Quality Assessment of Recombinant Proteins</a></li>

The Thermo Scientific Pierce HeLa Protein Digest Standard is a highly validated mammalian protein digest that may be used as a quality control sample for mass spectrometry (MS) analysis of complex proteomic samples.

Peptide retention time calibration mixture

The Thermo Scientific Pierce Peptide Retention Time Calibration Mixture enables reversed phase liquid chromatography (LC) and mass spectrometry (LC-MS) users to optimize and confirm correct operation of their equipment.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

Thermo Scientific Pierce EasyPep Mini MS Sample Prep Kit

Prepare your samples in less than 3 hours using pre-formulated reagents for analysis by mass spectrometry.

Thermo Scientific Acclaim 75 μm x20 mm, PepMap100 C18, 3 μm

Separate low abundance peptides in complex samples using the Acclaim PepMap LC columns.

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

 

<li><span class="icon-lt-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/CMD/posters/PN-64761-Recombinant-Proteins-ASMS2016-PN64761-EN.pdf" target="_blank">Poster Note: Development of Mass Spectrometry-Based Methods for Quality Assessment of Recombinant Proteins</a></li>

The Thermo Scientific Pierce HeLa Protein Digest Standard is a highly validated mammalian protein digest that may be used as a quality control sample for mass spectrometry (MS) analysis of complex proteomic samples.

Peptide retention time calibration mixture

The Thermo Scientific Pierce Peptide Retention Time Calibration Mixture enables reversed phase liquid chromatography (LC) and mass spectrometry (LC-MS) users to optimize and confirm correct operation of their equipment.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

Top

SureQuant Targeted Mass Spec Assay Kits

The Thermo Scientific SureQuant kits enable multiplex immunoprecipitation to mass spectrometry (mIP-MS) for the simultaneous enrichment and quantitation of multiple proteins.

Thermo Scientific Pierce EasyPep Mini MS Sample Prep Kit

Prepare your samples in less than 3 hours using pre-formulated reagents for analysis by mass spectrometry.

HeavyPeptide AQUA Custom Synthesis Service

Thermo Scientific Heavy Peptide AQUA Custom Synthesis Service provides isotopically labeled, AQUA-grade peptides for the relative and absolute quantitation of proteins at very low concentrations in complex protein mixtures. 

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

Thermo Scientific Acclaim PepMap 100 C18 LC Columns, 5µm, 20mm length, 0.1m I.D.

Separate low abundance peptides in complex samples using the Acclaim PepMap LC columns.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

* Only available for Thermo Scientific Orbitrap Eclipse Tribrid Mass Spectrometer.
SureQuant Targeted Mass Spec Assay Kits

The Thermo Scientific SureQuant kits enable multiplex immunoprecipitation to mass spectrometry (mIP-MS) for the simultaneous enrichment and quantitation of multiple proteins.

Thermo Scientific Pierce EasyPep Mini MS Sample Prep Kit

Prepare your samples in less than 3 hours using pre-formulated reagents for analysis by mass spectrometry.

HeavyPeptide AQUA Custom Synthesis Service

Thermo Scientific Heavy Peptide AQUA Custom Synthesis Service provides isotopically labeled, AQUA-grade peptides for the relative and absolute quantitation of proteins at very low concentrations in complex protein mixtures. 

Thermo Scientific EASY-Spray C18 LC column, 75 μm x 50 cm

With its outstanding peak capacity, the EASY-Spray C18 LC columns enable comprehensive proteome characterization.

Thermo Scientific Acclaim PepMap 100 C18 LC Columns, 5µm, 20mm length, 0.1m I.D.

Separate low abundance peptides in complex samples using the Acclaim PepMap LC columns.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

* Only available for Thermo Scientific Orbitrap Eclipse Tribrid Mass Spectrometer.

Technical resources

Top

Thermo Scientific Pierce Intact Protein Standard Mix

Used as a QC standard for method development and intact protein mass measurements, the Pierce Intact Protein Standard Mix is a mixture of recombinant proteins.

Thermo Scientific ProSwift RP-4H LC Columns

Compared to other bead-based columns, ProSwift RP-4H LC columns deliver superior resolution and faster separations.

PepSwift monolith 200 μm × 50 mm trap column

PepSwift Monolithic Capillary LC Columns are based on a polystyrene divinylbenzene copolymer, the monolithic structure offers a high-quality alternative to traditional microparticulate sorbents, providing important advantages to the chromatographic separation. High-sensitivity proteomics and biotech applications are easily performed using these columns.

ProSwift RP-4H LC Columns

Run fast protein separations at high linear velocities with these reversed-phase monolith columns which deliver the outstanding resolving power of nonporous analytical media combined with faster separations and analysis than other bead-based columns.

EASY-Spray LC columns

Ensure robust nano and capillary flow LC-MS with EASY-Spray LC Columns. The integrated column/emitter design eliminates dead volume and is temperature-controlled for maximum reliability and performance. Rigorously tested to ensure maximum quality, these columns are designed for maximum simplicity and ease-of-use.

MAbPac RP LC column

MAbPac RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over. The surface chemistry, particle size, and pore size, have been optimized for high resolution separations.

Thermo Scientific Ultimate 3000 UHPLC System

These proven LC systems will provide you with the versatility and ruggedness your laboratory requires all the way from method development to routine analysis.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Vanquish Horizon UHPLC System

For high-end UHPLC applications, use the Vanquish Horizon UHPLC system to achieve the highest sensitivity and precision, while spending less time on maintenance and set up.

BioPharma Finder

Access the extensive workflows in BioPharma Finder software to interpret and visualize results to get to the answers you need faster.

ProSightPC and ProSightPD Software

Perform comprehensive analysis of top-down and middle-down proteomics data with these data tools featuring robust search engines for proteoform characterization.

Thermo Scientific Pierce Intact Protein Standard Mix

Used as a QC standard for method development and intact protein mass measurements, the Pierce Intact Protein Standard Mix is a mixture of recombinant proteins.

Thermo Scientific ProSwift RP-4H LC Columns

Compared to other bead-based columns, ProSwift RP-4H LC columns deliver superior resolution and faster separations.

PepSwift monolith 200 μm × 50 mm trap column

PepSwift Monolithic Capillary LC Columns are based on a polystyrene divinylbenzene copolymer, the monolithic structure offers a high-quality alternative to traditional microparticulate sorbents, providing important advantages to the chromatographic separation. High-sensitivity proteomics and biotech applications are easily performed using these columns.

ProSwift RP-4H LC Columns

Run fast protein separations at high linear velocities with these reversed-phase monolith columns which deliver the outstanding resolving power of nonporous analytical media combined with faster separations and analysis than other bead-based columns.

EASY-Spray LC columns

Ensure robust nano and capillary flow LC-MS with EASY-Spray LC Columns. The integrated column/emitter design eliminates dead volume and is temperature-controlled for maximum reliability and performance. Rigorously tested to ensure maximum quality, these columns are designed for maximum simplicity and ease-of-use.

MAbPac RP LC column

MAbPac RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over. The surface chemistry, particle size, and pore size, have been optimized for high resolution separations.

Thermo Scientific Ultimate 3000 UHPLC System

These proven LC systems will provide you with the versatility and ruggedness your laboratory requires all the way from method development to routine analysis.

Thermo Scientific EASY-nLC 1200

Experience performance and throughput at 1200 bar with the easy to operate nano-flow UHPLC instrument.

Thermo Scientific Vanquish Horizon UHPLC System

For high-end UHPLC applications, use the Vanquish Horizon UHPLC system to achieve the highest sensitivity and precision, while spending less time on maintenance and set up.

BioPharma Finder

Access the extensive workflows in BioPharma Finder software to interpret and visualize results to get to the answers you need faster.

ProSightPC and ProSightPD Software

Perform comprehensive analysis of top-down and middle-down proteomics data with these data tools featuring robust search engines for proteoform characterization.

Top

Flyer: Higher Order Protein Structure Elucidation by HDX-MS
Hypersil GOLD C18 Selectivity LC Columns (50x1 mm, 1.9 um )

Achieve exceptional peak shape and resolution for your HPLC and LC/MS applications with Hypersil GOLD HPLC columns. These endcapped, ultrapure, silica-based columns deliver significant reduction in peak tailing using generic gradients with C18 selectivity. With their excellent resolution, efficiency, and sensitivity, Hypersil GOLD columns give you confidence in the accuracy and quality of your analytical data.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.

BioPharma Finder

Access the extensive workflows in BioPharma Finder software to interpret and visualize results to get to the answers you need faster.

Flyer: Higher Order Protein Structure Elucidation by HDX-MS
Hypersil GOLD C18 Selectivity LC Columns (50x1 mm, 1.9 um )

Achieve exceptional peak shape and resolution for your HPLC and LC/MS applications with Hypersil GOLD HPLC columns. These endcapped, ultrapure, silica-based columns deliver significant reduction in peak tailing using generic gradients with C18 selectivity. With their excellent resolution, efficiency, and sensitivity, Hypersil GOLD columns give you confidence in the accuracy and quality of your analytical data.

Thermo Scientific Ultimate 3000 RSLCnano

Take advantage of the wide flow rate range which gives you the flexibility you need for low flow applications.