Biology is complex. To decipher these complexities, metabolomics analysis demands sophisticated analytical technologies and software solutions. Our proven scientific network, publications and pioneering solutions driven by Thermo Scientific Orbitrap mass spectrometers enable broader and deeper analyses into the metabolome. Our industry-leading breadth in chromatographic separations, GC, LC and IC, combined with the technical depth of our systems and consumables, together produce novel, stringent and reproducible results for high impact discoveries.
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A comprehensive portfolio of chromatographic separations including gas, liquid and ion chromatography systems, chemistries and consumables to analyze the many diverse compounds in the metabolome.
Leading Orbitrap-based mass spectrometers provide the high-resolution, accurate-mass (HRAM) measurements and sensitivity required for metabolomics when combined with advanced separations. Fast data acquisition and polarity switching in a single run maximize productivity.
Data analysis for metabolomics typically consists of feature extraction, statistical analysis, compound identification and biological pathway analysis. The Thermo Scientific™ suite of metabolomics software products allows you to quickly transform complex data into useful results.
HRAM Orbitrap LC-MS is a widely adopted technique for lipidomics analyses. Together with a comprehensive database and library that provides accurate lipid identification, this technology enables relative as well as absolute quantitation from biological samples.
Comparing the relative abundances of all metabolites in multiple samples, without prior knowledge, is challenging. HRAM Orbitrap MS solutions provide the reproducibility, high sensitivity and wide dynamic range suited to such workflows. Application software turns data into results.
Verification and validation of defined known metabolite groups across large sample sets requires accuracy, high throughput and reliability. Targeted profiling is streamlined with our HRAM Orbitrap MS solutions, and routine SRM quantitation is easier with our triple quadrupole MS systems.
This series will lead you through experimental design, extracting the relevant information, increasing the confidence of your results, and finally bridging it all into biological information.
Metabolomics is a powerful analytical tool for the comprehensive detection of small molecules describing the biochemical phenotype in biological systems. By profiling polar metabolites and lipid species in biofluids and tissue samples, researchers gain knowledge of the physiology and pathophysiology of phenotypical endogenous metabolites and exogenous substances such as drugs or toxicants.
By collaborating with the scientific community, we’ve developed pioneering metabolomics solutions that deliver a comprehensive package to perform increasingly complex analyses from confident compound annotation to accurate quantitation.
Our LC-MS on-demand webinar series expands your application knowledge for pharma, biopharma, environmental, omics, food, forensics and clinical research and more. Learn how the latest high-performance mass spectrometry solutions can enable your laboratory to solve your most pressing analytical challenges, regardless of sample type.