Lipidomics Solutions

Lipidomics is a field of metabolomics that has evolved into a class all its own and aims to map and quantify lipid species sets within a cell or tissue to identify biomarkers and elucidate metabolism at the cellular level. Lipid species are diverse and complex, and the development of HRAM Thermo Scientific Orbitrap MS has risen to the challenge of lipid analysis, offering an unprecedented level of sensitivity, selectivity and precision.

Obtain valuable, quantitative insights from small- to large-scale studies across a variety of applications from untargeted, semi-targeted to targeted metabolomics and lipidomics studies. With optimized methods, the Thermo Scientific Orbitrap Exploris 240 mass spectrometer delivers a fast turnaround of sample to results with operational simplicity. Best-in-class performance together with Thermo Scientific AcquireX intelligent data acquisition delivers a fast track to confident results, all within a compact footprint, so you can go beyond with everyday versatility.

Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer surpasses these limits with new innovations that deliver the ultimate flexibility to expand experimental scope, and with built-in intelligence to ensure the highest data quality and confidence.

For routine and well characterized lipids, the Thermo Scientific TSQ Altis triple quadrupole mass spectrometer exceeds even the most stringent analytical requirements with superb sensitivity, speed and dynamic range for SRM-based targeted lipidomics applications.

Thermo Scientific LipidSearch software processes both HRAM Orbitrap and SRM triple quadrupole data, for the automatic identification and quantification of cellular lipids. It automatically generates reports from complex data to dramatically reduce analysis time.

Thermo Scientific TraceFinder software makes the challenging steps of unknown screening and targeted quantitation of lipids simple, fast and productive. It can be used with the full portfolio of Thermo Scientific quantitative mass spectrometers (both HRAM and triple quadrupole).