ADME/Tox Studies and Products
We strive to offer industry-leading ADME/Tox products that provide physiologically relevant results, so you can make the right decisions related to your compounds. We are a team of hepatic scientists helping fellow scientists—supporting IND and NDA submissions with our products and services, and participating in the advancement of research in 3D, enzyme induction, CYP inhibition, hepatic transport, and other metabolism-related (DMPK) fields and applications. We offer a comprehensive portfolio of tools to support your workflow across every step.
NEW Review our Primary Cells Workflow flyer today
Review our most recent posters from ISSX 2018 on 3D applications in Liver Modeling and Hepatic research:
Transition seamlessly through your workflow
Accurate ADME/Tox studies start with a consistent hepatic cell culture system. Backed by more than 50 years of cell culture experience, Gibco primary hepatocytes, media, and supplements provide the stable foundation you need to confidently screen compounds for potential effects to liver function. We can help you seamlessly integrate these powerful tools into your workflow.
Plate
We offer an extensive catalog of cells and matrices for plated or suspension 2D and 3D applications.
Culture
Our Gibco media and reagents provide superior growth conditions for hepatic cells.
Analyze
We offer instrumentation and reagents to support various downstream applications.
Featured ADME/Tox Products
The Gibco and Invitrogen brands by Thermo Fisher Scientific provide cell-based products to accelerate the discovery and development of effective drugs. Our comprehensive portfolio of hepatocytes, media, and supplements offer the stable foundation you need to confidently screen compounds for potential effects on liver function in both 2D and 3D models.
Review our offering of products to support your ADME/tox and DMPK needs and reach out to our team of hepatic scientists that can help you integrate these powerful tools in addition to providing hands-on training as you continue to make breakthroughs that will change the world of research and develop better therapies.
GIBCO Hepatocytes
Gibco human and animal hepatocytes and cell culture media, supplements & reagents
Transporter Products
GenoMembrane Transporter Vesicles and Transporter-qualified Hepatocytes
Toxicology Products
Assays to identify indicators of both biochemical and cellular toxicity
Nuclear Receptor ADME Assays
Our LanthaScreen PXR (SXR) and CAR Competitive Binding Assays contains all the reagents you need to conduct compound affinity testing
PCR-Based Drug Discovery Assays
Analyze drug discovery-related genes using our real-time PCR arrays
Resources
Support
Drug Discovery & Development Support Center
Find tips, troubleshooting help, and resources for support related to your drug discovery experiments.
For Research Use Only. Not for use in diagnostic procedures.
