Target-Based ADME/Tox Assays

We offer a collection of target-based ADME/Tox assays for drug discovery and development to help you determine the metabolic and safety profiles of lead candidates on a high throughput scale.

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Featured Target-Based ADME/Tox Assay Categories

	P450 Assays Fluorescent substrates and recombinant enzymes to evaluate your compound’s potential impact on P450 activity			Transporter Products GenoMembrane Transporter Vesicles and Transporter-qualified Hepatocytes to facilitate the prediction of your compounds modulation of transport enzyme activity

	Biochemical hERG Assays Detect hERG channel binding without radioactivity using our Predictor™ hERG Flourescence Polarization Assay Kit ideal for HTS applications			Nuclear Receptor ADME Assays Our LanthaScreen® Nuclear Receptor Competitive Binding Assay contains all the needed reagents you need to conduct compound affinity testing

	G-Protein Coupled Receptor Cellular ADME Assays Avoid off-target effects with our GPCR toxicity panel of validated cellular assays for selectivity screening			Toxicology Products Assays to identify indicators of both biochemical and cellular toxicity

	PCR-Based Drug Discovery Assays Analyze drug discovery-related genes using our real-time PCR arrays			Plasma Protein Binding Equilibrium Dialysis Rapid Equilibrium Dialysis (RED) device offers an easy, fast, and reliable system for performing plasma protein-binding assays, a critical step in drug development