Cytokines are secreted proteins that play a role in both the induction and effector phases of all immune and inflammatory responses, including cell proliferation, intercellular communication, and cell death. Chemokines are small cytokines which attract and recruit other cells into a localized area to exert their biologic effects. Growth factors include both cytokines and protein hormones, which stimulate proliferation as well as differentiation and maturation of responsive cells. Cytokines have been implicated not only in immunological conditions and inflammatory responses, but also in cancers and neurodegenerative disorders. The accurate quantitation of cytokines in biological samples such as plasma, serum, and tissue culture samples enables researchers to fully understand the mechanisms behind disease in physiological conditions.
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Invitrogen ELISA kits are developed to meet industry-standard specifications including standard calibration, precision, sensitivity, specificity, recovery, lot-to-lot consistency, and parallelism. Each protein is researched to target physiologically relevant sensitivity and tested in well-established models when available. These kits are manufactured in an ISO facility with stringent quality control to help ensure excellent quality and reproducibility.
This video demonstrates how to use an Invitrogen precoated sandwich ELISA kit for IL-6.
This video demonstrates how to use the Invitrogen precoated sandwich ELISA kit for IL-10.