Peroxisomes are bound by a single membrane and can be found in most eukaryotic cells. They bud off of the endoplasmic reticulum and function primarily to enzymatically oxidize fatty acids and then catalyze the breakdown of hydrogen peroxide, a result of fatty acid degradation. In plant cells, peroxisomes assist chloroplasts in photorespiration and convert fatty acids to sugar. In mammals, they are critical in preserving the normal function of brain and lungs and play a role in energy metabolism.
Peroxisome marker antibodies can aid in the study of peroxisome dynamics and structure.. Peroxisome marker antibodies can also help elucidate the role or roles a protein may play in the tasks that are performed by peroxisomes. Peroxisome marker antibodies are particularly useful in targeting peroxisomes in fixed cells. Invitrogen peroxisome marker antibodies are designed to dependably detect the key peroxisome targets. Each antibody is validated for use in various applications. Key peroxisome marker targets include:
Immunofluorescent analysis of FOXP2 in RH-30 cells using a FOXP2 monoclonal antibody (Cat. No. MA5-31419). The analysis shows specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red.
Immunohistochemical analysis of PEX19 in the cytosol of paraffin-embedded mouse testis tissue using a PEX19 polyclonal antibody (Cat. No. PA5-22129) at a dilution of 1:500.