Large-Scale Process Chromatography
Utilized in multiple processes, these breakthrough resins combine optimal particle size and pore structure with a rigid backbone and proprietary chemistries. POROS™ 50 µm resins demonstrate exceptionally high resolution, dynamic binding capacity, and capture efficiency over a range of flow rates and are primarily used in polish applications.
CaptureSelect™ affinity resins offer superior selectivity resulting in higher yields and improved purity in the initial capture step. We have developed numerous products for large-scale purification of various biologics such as antibodies and antibody fragments, fusion proteins, hormones, and viruses.
POROS™ resins are manufactured from approved raw materials to finished product using advanced, proprietary processes that make us unique in this industry. A 30,000 square foot, state-of-the-art chemical facility, in Bedford, Massachusetts, is dedicated to the production of all the POROS™ chromatography resins. Quality testing is performed at all stages to ensure excellent lot-to-lot consistency. POROS chromatography resins are manufactured under ISO 9001:2008 and ISO 13485:2003 standards.
- CaptureSelect™ Bioprocess Products
CaptureSelect™ affinity ligands, based on Camelid-derived single domain antibody fragments, are available for use in large-scale manufacturing processes. Paired leakage assays offer additional tools for process development or for routine quality control processes.
- POROS™ MabCapture™ A Select Resin
POROS™ MabCapture™ A Select is a new high-throughput, lower-priced Protein A chromatography resin, combining past improvements to MabCapture A with our own Protein A ligand, enabling the same high-throughput purification performance at a significant reduction in price over most Protein A chromatography resins
- POROS™ MabCapture™ A Resin
A high performance Protein A chromatography resin technology combining improvements made in bead and chemistry technology to provide high dynamic binding capacities and excellent capture efficiencies at high linear velocities
- POROS™ Heparin 50 µm Bulk Resin
Heparin affinity media for process-scale separation of biomolecules with specific Heparin binding affinity, such as growth factors and other serum components, including coagulation factors and nucleotide binding proteins.
- POROS™ XQ 50 µm Bulk Resin
A next-generation strong anion exchange resin that delivers a combination of high capacity, high resolution, and high salt tolerance for greater process flexibility and performance.
- POROS™ XS 50 µm Bulk Resin
A next-generation strong cation exchange resin that delivers a combination of high capacity, high resolution, and high salt tolerance for greater process flexibility and performance.
- POROS™ HS 50 µm Bulk Resin
A strong cation exchange resin offering high resolution for the removal of process contaminants and product impurities in downstream polish applications
- POROS™ HQ 50 µm Bulk Resin
A strong anion exchange resin providing high resolution with high protein binding capacity and efficiency
- POROS™ D 50 µm Bulk Resin
A weak anion exchange resin providing a high through-put alternative to traditional DEAE resins
- POROS™ PI 50 µm Bulk Resin
A weak anion exchange resin delivering unique selectivity due to its polyethyline imine functional group.
- GoPure™ 1.2 cm Diameter Column
Suitable for media screening or bench-scale purification. It is ideal for scale-down models of process chromatography unit operations (such as viral clearance studies). Column volumes are 5 to 20 mL.
Pharmaceutical Grade Reagent. For Manufacturing and Laboratory Use Only.