Large-Scale Process Chromatography
When you need high performance and high throughput on a large scale, POROS bulk chromatography resins are the industry standard for process-scale bioseparations. Utilized in multiple processes, these breakthrough resins combine optimal particle size and pore structure with a rigid backbone and proprietary chemistries. POROS 50 µm resins demonstrate exceptionally high resolution, dynamic binding capacity, and capture efficiency over a range of flow rates and are primarily used in polish applications.
CaptureSelect affinity resins offer superior selectivity resulting in higher yields and improved purity in the initial capture step. We have developed numerous products for large-scale purification of various biologics such as antibodies and antibody fragments, fusion proteins, hormones, and viruses.
CaptureSelect affinity ligands, based on Camelid-derived single domain antibody fragments, are available for use in large-scale manufacturing processes. Paired leakage assays offer additional tools for process development or for routine quality control processes.
- POROS MabCapture A Select Resin
POROS™ MabCapture™ A Select is a new high-throughput, lower-priced Protein A chromatography resin, combining past improvements to MabCapture A with our own Protein A ligand, enabling the same high-throughput purification performance at a significant reduction in price over most Protein A chromatography resins
- POROS Heparin 50 µm Bulk Resin
Heparin affinity media for process-scale separation of biomolecules with specific Heparin binding affinity, such as growth factors and other serum components, including coagulation factors and nucleotide binding proteins.
- POROS XQ 50 µm Bulk Resin
A next-generation strong anion exchange resin that delivers a combination of high capacity, high resolution, and high salt tolerance for greater process flexibility and performance.
- POROS XS 50 µm Bulk Resin
A next-generation strong cation exchange resin that delivers a combination of high capacity, high resolution, and high salt tolerance for greater process flexibility and performance.
- POROS HS 50 µm Bulk Resin
A strong cation exchange resin offering high resolution for the removal of process contaminants and product impurities in downstream polish applications
- POROS HQ 50 µm Bulk Resin
A strong anion exchange resin providing high resolution with high protein binding capacity and efficiency
- POROS D 50 µm Bulk Resin
A weak anion exchange resin providing a high through-put alternative to traditional DEAE resins
- POROS PI 50 µm Bulk Resin
A weak anion exchange resin delivering unique selectivity due to its polyethyline imine functional group.
- GoPure 1.2 cm Diameter Column
Suitable for media screening or bench-scale purification. It is ideal for scale-down models of process chromatography unit operations (such as viral clearance studies). Column volumes are 5 to 20 mL.
Pharmaceutical Grade Reagent. For Manufacturing and Laboratory Use Only.