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EvolveD pre-packed columns for biopharmaceutical applications

Large volume pre-packed chromatography columns are a cost-effective alternative for the purification of biologics. The use of these columns eliminates the need for column packing, column qualification and cleaning thereby saving precious time, resources and costs.

Increase flexibility and productivity in your downstream purification process with our ready to-use pre-packed chromatography columns for bioprocess applications. The EvolveD columns are available in different diameters and bed heights. The columns are pre-packed with our unique CaptureSelect affinity matrices, which provide high target purity and yield in a single step.

Designed specifically for use in biopharmaceutical applications, these pre-packed columns are suitable for cGMP manufacturing and have the following features:

  • Prepared and packed in a ISO 7 classified environment
  • Qualified in terms of performance and pressure flow characteristics
  • Suitable for direct connection to standard chromatography systems
  • Regulatory support documents are available for the column hardware and for the resin
  • Non-metallic flow path eliminates corrosion risk and contamination of the process, allowing for use of high salt concentrations (when needed)
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The columns are available in a variety of diameters and bed heights and have the following specifications:

Column type 10 cm bed height 20 cm bed height
Column diameter 7 cm 10 cm 20 cm 7 cm 10 cm 20 cm
Column length 10 cm 10 cm 10 cm 20 cm 20 cm 20 cm
Cross-sectional area (cm2) 38.5 78.5 314.2 38.5 78.5 314.2
Column volume 385 mL 785 mL 3142 mL 770 mL 1570 mL 6284 mL

Operating and technical specifications

  • Pressure rating (bar/psi): 4/58
  • Operating temperature*: 2-30°C
  • Bed support size (µm): 8 µm
  • Inlet/outlet internal diameter (mm): 3mm or 6 mm depending on the column diameter
  • Inlet/outlet port connections: 25 mm TC sanitary fitting

* The operating temperature will be dependent on the resin packed

Find your EvolveD pre-packed column by resin type

All bioprocess columns are pre-packed with a CaptureSelect Affinity Matrix. The CaptureSelect affinity chromatography resins offer a unique affinity purification solution based on Camelid-derived single domain [VHH] antibody fragments. The affinity resins provide high target purity in a single step, independent of feedstock. The affinity ligands are developed to meet all predefined requirements such as high specificity to the target molecule, mild elution during the purification process and high stability of the final resin. Manufacturing in an animal free production process allows for use in commercial purification processes.

Packed affinity matrix Purifies Column volumes Bed height (cm) Column diameter (cm) Product number
CaptureSelect CH1-XL
  • Fab fragments
  • Human IgG
385 mL 10 7 6943462071
770 mL 20 7 6943462072
785 mL 10 10 6943462101
1570 mL 20 10 6943462102
3142 mL 10 20 6943462201
6284 mL 20 20 6943462202
Packed affinity matrix Purifies Column volumes Bed height (cm) Column diameter (cm) Product number
CaptureSelect KappaXP
  • Human IgG
  • Fab fragments containing a Kappa light chain
385 mL 10 7 6943212071
770 mL 20 7 6943212072
785 mL 10 10 6943212101
1570 mL 20 10 6943212102
3142 mL 10 20 6943212201
6284 mL 20 20 6943212202
Packed affinity matrix Purifies Column volumes Bed height (cm) Column diameter (cm) Product number
CaptureSelect FcXL
  • Human IgG
  • Fc-fusion proteins
  • Non protein A binding IgGs
385 mL 10 7 6943280071
770 mL 20 7 6943280072
785 mL 10 10 6943280101
1570 mL 20 10 6943280102
3142 mL 10 20 6943280201
6284 mL 20 20 6943280202

Take advantage of our unique portfolio of affinity resins to help you develop biosimilars, biobetters, and other types of recombinant proteins.

Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect HSA Human serum albumin, albumin fusion proteins 385 mL 10 6942970071
770 mL 20 6942970072
785 mL 10 6942970101
1570 mL 20 6942970102
3142 mL 10 6942970201
6284 mL 20 6942970202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect HGH Recombinant human growth hormone 385 mL 10 6943160071
770 mL 20 6943160072
785 mL 10 6943160101
1570 mL 20 6943160102
3142 mL 10 6943160201
6284 mL 20 6943160202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect FSH Human follicle stimulating hormone 385 mL 10 6943180071
770 mL 20 6943180072
785 mL 10 6943180101
1570 mL 20 6943180102
3142 mL 10 6943180201
6284 mL 20 6943180202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect hCG the alpha chain of human chorionic gonadotropin 385 mL 10 6943410071
770 mL 20 6943410072
785 mL 10 6943410101
1570 mL 20 6943410102
3142 mL 10 6943410201
6284 mL 20 6943410202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect tPA human tissue plasminogen activator 385 mL 10 6943430071
770 mL 20 6943430072
785 mL 10 6943430101
1570 mL 20 6943430102
3142 mL 10 6943430201
6284 mL 20 6943430202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect TSH human thyroid stimulating hormone 385 mL 10 6943562071
770 mL 20 6943562072
785 mL 10 6943562101
1570 mL 20 6943562102
3142 mL 10 6943562201
6284 mL 20 6943562202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect C-tagXL C-tag fusion proteins (C-tag sequence: EPEA) 385 mL 10 6943072071
770 mL 20 6943072072
785 mL 10 6943072101
1570 mL 20 6943072102
3142 mL 10 6943072201
6284 mL 20 6943072202
Packed affinity matrix Purifies Column volumes Bed height (cm) Column diameter (cm) Product number
CaptureSelect CH1-XL
  • Fab fragments
  • Human IgG
385 mL 10 7 6943462071
770 mL 20 7 6943462072
785 mL 10 10 6943462101
1570 mL 20 10 6943462102
3142 mL 10 20 6943462201
6284 mL 20 20 6943462202
Packed affinity matrix Purifies Column volumes Bed height (cm) Column diameter (cm) Product number
CaptureSelect KappaXP
  • Human IgG
  • Fab fragments containing a Kappa light chain
385 mL 10 7 6943212071
770 mL 20 7 6943212072
785 mL 10 10 6943212101
1570 mL 20 10 6943212102
3142 mL 10 20 6943212201
6284 mL 20 20 6943212202
Packed affinity matrix Purifies Column volumes Bed height (cm) Column diameter (cm) Product number
CaptureSelect FcXL
  • Human IgG
  • Fc-fusion proteins
  • Non protein A binding IgGs
385 mL 10 7 6943280071
770 mL 20 7 6943280072
785 mL 10 10 6943280101
1570 mL 20 10 6943280102
3142 mL 10 20 6943280201
6284 mL 20 20 6943280202

Take advantage of our unique portfolio of affinity resins to help you develop biosimilars, biobetters, and other types of recombinant proteins.

Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect HSA Human serum albumin, albumin fusion proteins 385 mL 10 6942970071
770 mL 20 6942970072
785 mL 10 6942970101
1570 mL 20 6942970102
3142 mL 10 6942970201
6284 mL 20 6942970202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect HGH Recombinant human growth hormone 385 mL 10 6943160071
770 mL 20 6943160072
785 mL 10 6943160101
1570 mL 20 6943160102
3142 mL 10 6943160201
6284 mL 20 6943160202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect FSH Human follicle stimulating hormone 385 mL 10 6943180071
770 mL 20 6943180072
785 mL 10 6943180101
1570 mL 20 6943180102
3142 mL 10 6943180201
6284 mL 20 6943180202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect hCG the alpha chain of human chorionic gonadotropin 385 mL 10 6943410071
770 mL 20 6943410072
785 mL 10 6943410101
1570 mL 20 6943410102
3142 mL 10 6943410201
6284 mL 20 6943410202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect tPA human tissue plasminogen activator 385 mL 10 6943430071
770 mL 20 6943430072
785 mL 10 6943430101
1570 mL 20 6943430102
3142 mL 10 6943430201
6284 mL 20 6943430202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect TSH human thyroid stimulating hormone 385 mL 10 6943562071
770 mL 20 6943562072
785 mL 10 6943562101
1570 mL 20 6943562102
3142 mL 10 6943562201
6284 mL 20 6943562202
Packed affinity matrix Purifies Column volumes Bed height (cm) Product number
CaptureSelect C-tagXL C-tag fusion proteins (C-tag sequence: EPEA) 385 mL 10 6943072071
770 mL 20 6943072072
785 mL 10 6943072101
1570 mL 20 6943072102
3142 mL 10 6943072201
6284 mL 20 6943072202

* All columns are made to order and require a minimum order quantity of 2 prepacked columns. EvolveD is a registered trademark of Delta Precision Ltd

Bioprocessing resources

Access a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing: