Immunology at Work is here for you, whether you want to review the basics, gain more in-depth knowledge, or discover the latest research tools. This resource hub contains rich and reliable technical content designed for new and experienced life scientists alike exploring the field of immunology.

 


Natural Killer cells

NK cells kill pathogen infected cells and cancer cells. They also release cytokines, which alert and attract other immune cells.

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T Helper 1 cells

Lineage of CD4+ T helper cells that promote immune response required for host defense against intracellular viral and bacterial pathogens.

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T Follicular Helper cells

Subset of CD4+ T helper cells that trigger germinal center B cells into antibody-secreting plasma and memory B cells.

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Monocytes

Circulating immune cells that engulfs (phagocytosis) and activates other immune cells.

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T Helper 2 cells

Lineage of CD4+ T helper cells that promote humoral immunity critical for host defense against extracellular pathogens.

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Cytotoxic T cells

T cells, also know as CD8+ cells, that kill virus infected cells and cancer cells by releasing toxic chemicals.

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Macrophages

Professional phagocytic tissue resident cells that destroy foreign antigens/cells by phagocytosis. They release cytokines that attract and activates other immune cells.

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Regulatory T cells

T cells critical to the maintenance of self-tolerance and immune cell homeostasis.

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Dendritic cells

Phagocytic antigen presenting cells with an important role in alerting T cells to new pathogens. They act as key mediators between the innate and adaptive immune systems.

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T Helper 17 cells

CD4+ T helper cells that play a critical role in the activation of other immune cells such as B cells and cytotoxic T cells, as well as in the regulation of immune responses.

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Viral Immunology

Viral life cycle

Find information on viral attachment and entry, replication, maturation, and release.

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Interferons

Interferon (IFN) proteins are a family of cytokines secreted by host cells to modulate the immune response. Find information on interferon types and induction.

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Pro-inflammatory cytokines

Cytokines are small secreted proteins that are key modulators of inflammation. Discover how pro-inflammatory cytokines play a role in the immune response.

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Viral life cycle

Find information on viral attachment and entry, replication, maturation, and release.

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Interferons

Interferon (IFN) proteins are a family of cytokines secreted by host cells to modulate the immune response. Find information on interferon types and induction.

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Pro-inflammatory cytokines

Cytokines are small secreted proteins that are key modulators of inflammation. Discover how pro-inflammatory cytokines play a role in the immune response.

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Protocols for Immunology

Apply the background information provided throughout this resource center with practical and relevant application protocols. Browse by application or technique:

Cell preparation and immune cell stimulation

Cell preparation and immune cell stimulation

Find detailed protocols on the isolation of the different immune cells starting from whole blood or lymphoid tissue and various methods to stimulate them.

Sample preparation

Sample preparation

Protocols covering isolation of RNA from immune cells to sample preparation for immunoassays.

Flow cytometry

Flow cytometry

Detailed protocols on staining, compensation, and validated antibody panels.

Immunoassays

Immunoassays

Find general protocols for ELISA, western blot analysis, and immunohistochemistry.

 

Research Tools for Immunology

Digital tools to make your experimental planning easier.

 

Meet the Scientists

Learn about the scientists who helped put this resource center together.

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Meet the Scientists
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