Dynabeads® are used for the isolation of a range of different species. Below are some citations. For further information, please contact our Technical Service.

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Non-Human Primate Cells

Here are a couple of examples of how Dynabeads® can be used with your own antibodies to isolate human primate cells.

Chimpanzee CD4+ T Cells
Shoukry NHet al (2004) Conserved hierarchy of helper T cell responses in a chimpanzee during primary and secondary Hepatitis C virus infections. J. Immunol. 172: 483–492.

Product used: Dynabeads® CD4.

Macaque CD8+ T Cell Depletion
Mackay GAet al (2004) Protection against late-onset AIDS in macaques prophylactically immunized with a live simian HIV vaccine was dependent on persistence of the vaccine virus. J. Immunol. 173: 4100–4107.

Product used: Dynabeads® Sheep anti-Mouse IgG

Rat Cells

Here are some examples of how secondary-coated or surface-activated Dynabeads® can be used with your own antibodies to isolate various rat cell types.

Rat Osteoclasts
Zhao H et al (2001) Down-regulation of Small GTPase Rab7 Impairs Osteoclast Polarization and Bone Resorption J. Biol. Chem. 276 (42): 39295–39302.

Product used: Dynabeads® Sheep anti-Mouse IgG

Rat Dendritic Cells
Chauveau C et al (2005) Heme oxygenase-1 expression inhibits dendritic cell maturation and pro-inflammatory function but conserves IL-10 expression. Blood 106: 1694 – 1702.

Product used: Dynabeads® Sheep anti-Rat IgG

Rat Mast Cells
Jamur MC et al (2001) Identification and isolation of rat bone marrow-derived mast cells using the mast cell-specific monoclonal antibody AA4. J Histochem Cytochem 49:219–228.

Product used: Dynabeads® M-450 Tosylactivated

Cat Cells

Here is an example of how Dynabeads® can be used with your own antibody to isolate cat cells.

Cat Regulatory T cells
Vahlenkamp TW et al (2004) Feline immunodeficiency virus infection phenotypically and functionally activates immunosuppressive CD4 +CD25 + T regulatory cells. J.Immunol. 172:4752-61.

Product used: Dynabeads® Goat anti-Mouse IgG

Combine Dynabeads® with your own antibody

Product Starting sample Benefits
Streptavidin Dynabeads®
Dynabeads® FlowComp™ Flexi
Single Cell Suspensions Combine with your own antibody of choice to isolate any cell type from any species. This kit provides everything you need for labeling of antibodies and subsequent cell isolation. Beads are removed after isolation - you obtain pure and viable cells suitable for any downstream application.
CELLection™ Biotin Binder Whole blood, MNC Use with any biotinylated antibody to positively isolate cells from any species. Beads and antibodies are removed after isolation - you obtain pure and viable cells for use in any application. [More info]
Dynabeads® Biotin Binder Whole blood, MNC Isolate any cell from any species. This kit bind all biotinylated antibodies and is our most flexible secondary product for cell isolation or depletion. [More info]
Secondary coated Dynabeads®
Dynabeads® Sheep anti-Rat IgG Whole blood, MNC Isolate any cell type from any species except rat. For use with your primary IgG rat antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads® Pan Mouse IgG Whole blood, MNC A flexible secondary product for cell isolation or depletion. It will bind all subclasses of mouse IgG and is Fc specific. Requires less antibody and has shown no cross reactivity to human, rat, hamster, goat, rabbit and guinea pig IgG.
CELLection™ Pan Mouse IgG Whole blood, MNC Use with any mouse IgG to positively isolate cells from any species EXCEPT mouse. Beads can be removed after isolation to leave pure and viable cells for use in any application.
Dynabeads® Sheep anti-Mouse IgG Whole blood, MNC Isolate any cell type from any species except mouse. For use with your primary mouse IgG1, IgG2a or IgG2b antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells. Also available in clinical research grade as Dynabeads® ClinExVivo™ Sheep anti-Mouse IgG.
Dynabeads® Goat anti-Mouse IgG Whole blood, MNC Isolate any cell type from any species except mouse. For use with your primary IgG mouse antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads® Rat anti-Mouse IgG1 Whole blood, MNC Isolate any cell type from any species except mouse. For use with your primary mouse IgG1 antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads® Rat anti-Mouse IgM Whole blood, MNC Isolate any cell type from any species except mouse. For use with your primary mouse IgM antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads® Sheep anti-Rabbit IgG Whole blood, MNC Isolate any cell type from any species except rabbit. For use with your primary rabbit antibody of choice. This product can be used for eucaryotic cells.
Surface activated Dynabeads®
Dynabeads® M-450 Epoxy Whole blood, MNC Hydrophobic naked beads with glycidyl ether (epoxy) reactive groups. Ideal for coupling of antibodies for cell applications. Coupling reactions can be performed at neutral pH, with 24 hour incubation at room temperature. Also available in clinical research grade as Dynabeads® ClinExVivo™ Epoxy.
Dynabeads® M-450 Tosylactivated Whole blood, MNC Hydrophobic naked beads with p-toluenesulphonyl (tosyl) reactive groups. For coupling of antibodies for cell applications. Coupling reactions can be performed at neutral pH although high pH and incubation at 37°C will promote covalent binding.