Dynabeads products are used for the isolation of a range of different species-specific cell populations. Below you can read a selection of publications detailing the application of Dynabeads products in addition to links to related products.

For further information, please contact our Technical Service.

Dynabead products in the literature—select publications:

See also:

Dynabeads products in the literature – reviews and research of practical applications

Read about practical applications of Dynabeads products to isolate cell types in a species-specific manner. These publications highlight the utility of Dynabeads products in positive cell isolation, negative cell isolation and depletion of cell types from mixed cell populations.

Cell typeProductReference
Non-human primate cells
Chimpanzee CD4+ T cellsDynabeads CD4Shoukry NHet al (2004) Conserved hierarchy of helper T cell responses in a chimpanzee during primary and secondary Hepatitis C virus infections. J. Immunol. 172: 483–492.
Macaque CD8+ T cell depletionDynabeads Sheep anti-Mouse IgGMackay GAet al (2004) Protection against late-onset AIDS in macaques prophylactically immunized with a live simian HIV vaccine was dependent on persistence of the vaccine virus. J. Immunol. 173: 4100–4107.
Rat cells
Rat osteoclasts Dynabeads Sheep anti-Mouse IgGZhao H et al (2001) Down-regulation of Small GTPase Rab7 Impairs Osteoclast Polarization and Bone Resorption J. Biol. Chem. 276 (42): 39295–39302.
Rat dendritic cells Dynabeads Sheep anti-Rat IgGChauveau C et al (2005) Heme oxygenase-1 expression inhibits dendritic cell maturation and pro-inflammatory function but conserves IL-10 expression. Blood 106: 1694 – 1702.
Rat mast cellsDynabeads M-450 TosylactivatedJamur MC et al (2001) Identification and isolation of rat bone marrow-derived mast cells using the mast cell-specific monoclonal antibody AA4. J Histochem Cytochem 49:219–228.
Cat cells
Cat regulatory T cells Dynabeads Goat anti-Mouse IgGVahlenkamp TW et al (2004) Feline immunodeficiency virus infection phenotypically and functionally activates immunosuppressive CD4 +CD25 + T regulatory cells. J.Immunol. 172:4752-61.

Combine Dynabeads products with your own antibody

ProductStarting sampleBenefits
Dynabeads FlowComp FlexiSingle Cell SuspensionsCombine with your own antibody of choice to isolate any cell type from any species. This kit provides everything you need for labeling of antibodies and subsequent cell isolation. Beads are removed after isolation—you obtain pure and viable cells suitable for any downstream application.
CELLection Biotin BinderWhole blood, MNCUse with any biotinylated antibody to positively isolate cells from any species. The beads are removed after isolation—you obtain pure and viable cells for use in any application. [More info]
Dynabeads Biotin BinderWhole blood, MNCIsolate any cell from any species. This kit bind all biotinylated antibodies and is our most flexible secondary product for cell isolation or depletion. [More info]
ProductStarting sampleBenefits
Dynabeads Sheep anti-Rat IgGWhole blood, MNCIsolate any cell type from any species except rat. For use with your primary IgG rat antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads Pan Mouse IgGWhole blood, MNCA flexible secondary product for cell isolation or depletion. It will bind all subclasses of mouse IgG and is Fc specific. Requires less antibody and has shown no cross reactivity to human, rat, hamster, goat, rabbit and guinea pig IgG.
CELLection Pan Mouse IgGWhole blood, MNCUse with any mouse IgG to positively isolate cells from any species EXCEPT mouse. Beads can be removed after isolation to leave pure and viable cells for use in any application.
Dynabeads Sheep anti-Mouse IgGWhole blood, MNCIsolate any cell type from any species except mouse. For use with your primary mouse IgG1, IgG2a or IgG2b antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells. Also available in clinical research grade as Dynabeads ClinExVivo Sheep anti-Mouse IgG.
Dynabeads Goat anti-Mouse IgGWhole blood, MNCIsolate any cell type from any species except mouse. For use with your primary IgG mouse antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads Rat anti-Mouse IgG1Whole blood, MNCIsolate any cell type from any species except mouse. For use with your primary mouse IgG1 antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads Rat anti-Mouse IgMWhole blood, MNCIsolate any cell type from any species except mouse. For use with your primary mouse IgM antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads Sheep anti-Rabbit IgGWhole blood, MNCIsolate any cell type from any species except rabbit. For use with your primary rabbit antibody of choice. This product can be used for eucaryotic cells.
ProductStarting sampleBenefits
Dynabeads
M-450 Epoxy		Whole blood, MNCHydrophobic naked beads with glycidyl ether (epoxy) reactive groups. Ideal for coupling of antibodies for cell applications. Coupling reactions can be performed at neutral pH, with 24 hour incubation at room temperature. Also available in clinical research grade as Dynabeads ClinExVivo Epoxy.
Dynabeads
M-450 Tosylactivated		Whole blood, MNCHydrophobic naked beads with p-toluenesulphonyl (tosyl) reactive groups. For coupling of antibodies for cell applications. Coupling reactions can be performed at neutral pH although high pH and incubation at 37°C will promote covalent binding.
Streptavidin Dynabeads
ProductStarting sampleBenefits
Dynabeads FlowComp FlexiSingle Cell SuspensionsCombine with your own antibody of choice to isolate any cell type from any species. This kit provides everything you need for labeling of antibodies and subsequent cell isolation. Beads are removed after isolation—you obtain pure and viable cells suitable for any downstream application.
CELLection Biotin BinderWhole blood, MNCUse with any biotinylated antibody to positively isolate cells from any species. The beads are removed after isolation—you obtain pure and viable cells for use in any application. [More info]
Dynabeads Biotin BinderWhole blood, MNCIsolate any cell from any species. This kit bind all biotinylated antibodies and is our most flexible secondary product for cell isolation or depletion. [More info]
Secondary coated Dynabeads
ProductStarting sampleBenefits
Dynabeads Sheep anti-Rat IgGWhole blood, MNCIsolate any cell type from any species except rat. For use with your primary IgG rat antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads Pan Mouse IgGWhole blood, MNCA flexible secondary product for cell isolation or depletion. It will bind all subclasses of mouse IgG and is Fc specific. Requires less antibody and has shown no cross reactivity to human, rat, hamster, goat, rabbit and guinea pig IgG.
CELLection Pan Mouse IgGWhole blood, MNCUse with any mouse IgG to positively isolate cells from any species EXCEPT mouse. Beads can be removed after isolation to leave pure and viable cells for use in any application.
Dynabeads Sheep anti-Mouse IgGWhole blood, MNCIsolate any cell type from any species except mouse. For use with your primary mouse IgG1, IgG2a or IgG2b antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells. Also available in clinical research grade as Dynabeads ClinExVivo Sheep anti-Mouse IgG.
Dynabeads Goat anti-Mouse IgGWhole blood, MNCIsolate any cell type from any species except mouse. For use with your primary IgG mouse antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads Rat anti-Mouse IgG1Whole blood, MNCIsolate any cell type from any species except mouse. For use with your primary mouse IgG1 antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads Rat anti-Mouse IgMWhole blood, MNCIsolate any cell type from any species except mouse. For use with your primary mouse IgM antibody of choice. Ideal for positive isolation, negative isolation or depletion of cells.
Dynabeads Sheep anti-Rabbit IgGWhole blood, MNCIsolate any cell type from any species except rabbit. For use with your primary rabbit antibody of choice. This product can be used for eucaryotic cells.
Surface activated Dynabeads
ProductStarting sampleBenefits
Dynabeads
M-450 Epoxy		Whole blood, MNCHydrophobic naked beads with glycidyl ether (epoxy) reactive groups. Ideal for coupling of antibodies for cell applications. Coupling reactions can be performed at neutral pH, with 24 hour incubation at room temperature. Also available in clinical research grade as Dynabeads ClinExVivo Epoxy.
Dynabeads
M-450 Tosylactivated		Whole blood, MNCHydrophobic naked beads with p-toluenesulphonyl (tosyl) reactive groups. For coupling of antibodies for cell applications. Coupling reactions can be performed at neutral pH although high pH and incubation at 37°C will promote covalent binding.

Related Dynabeads products and information

Resources

Literature

For Research Use Only. Not for use in diagnostic procedures.