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          • Cell Structure

          Cell Structure

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          ‹Cell Analysis
          • Antibodies ›
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          • Cellular Imaging ›
          • Cell Structure
            • Cytoskeleton
            • Endoplasmic Reticulum Structure
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          Schematic of a whole cell with the various cell structures labeled
           Click image to enlarge

          Organelle structures play a critical role in cellular function, and the detection of specific cell structures is key in fluorescence imaging of cells and tissue. Cell structure labels can be a counterstain method to identify the location of specific proteins and targets of interest within the cell. Our cell labels include cell structure specific dyes or antibodies for live-cell or fixed-cell imaging, as well as for flow cytometry.

          Cell structure protocols

          Schematic of actin filaments

          Cytoskeleton Structure

          Actin, tubulin, and talin stains and fluorescent proteins for use in live or fixed cells.
          Learn about phalloidin staining

          Schematic of endoplasmic reticulum

          Endoplasmic Reticulum Structure

          Cell-permeant or fluorescent fusion proteins that bind the ER in live cells.
           

          Schematic of endosome vesicle

          Endosome Structure

          Fluorescent fusion proteins that target early or late endosomes in live cells.
           


          Schematic of Golgi complex

          Golgi Apparatus Structure

          Cell labels that target Golgi lipids or fluorescent proteins that target a Golgi enzyme in live cells.
           

          Lysosome structure

          Lysosome Structure

          Live cell markers to target and track acidic organelles or fluorescent proteins that bind the lysosome membrane.

          Schematic of mitochondria

          Mitochondria Structure

          Cell labels based on mitochondria membrane potential or fluorescent proteins for use in live cells.


          Schematic of nucleus and nucleolus

          Nucleus Structure

          Cell-permeant and cell-impermeant stains for the nucleus, nuclear components, and nucleolus.

          Schematic of peroxisome vesicle

          Peroxisome Structure

          Fluorescent proteins for live cells or antibodies for staining peroxisomes in fixed cells.

          Plasma membrane structure

          Plasma Membrane Structure

          WGA conjugates, cell membrane stains, and fluorescent fusion proteins for staining cell membranes.

          Fluorescent conjugates for lectin labeling

          Microscopic image of cells stained with green lectin spermatozoa, red actin, blue nuclei

          Thermo Fisher Scientific offers an extensive portfolio of highly purified and specific fluorescently conjugated lectins. These lectins come in a variety of dyes including bright Alexa Fluor Dyes, Dylight Dyes, and other classic dyes, to provide bright and sharp images of cells for specific glycoprotein detection. Fluorescent conjugation allows you to easily localize and detect cell-surface or intracellular glycoproteins, making them a versatile primary detection approach for imaging or flow cytometry applications.

          Learn more about lectins

          CellLight fluorescent protein labeling

          Microscopic image of cells labeled with green mitochondria fusion protein, red talin cytoskeletal fusion protein, and blue nucleus stain

          CellLight fusion proteins provide an easy way to label specific structures in live cells with fluorescent proteins. Simply add the reagent to your cells, incubate overnight, and you’re ready to image in the morning. These ready-to-use constructs express fluorescent fusion proteins targeted to specific intracellular structures. The fluorescent protein is introduced using a simple transfection step that doesn’t require molecular biology techniques to carry out—it works like a cell stain.

          Learn more about CellLight proteins

          Resources

          Molecular Probes Handbook

          • Probes for Cytoskeletal Proteins—Chapter 11
          • Probes for Organelles—Chapter 12
          • Probes for Lipids and Membranes—Chapter 13

          BioProbes 70 Journal article

          • Journal Club—An In-Depth Look at Fluorescent Dyes for Organelle Labeling

          Research tools

          • Cell staining tool
          • Fluorescence SpectraViewer

          Cell Structure Information
          Find educational resources such as application notes, webinars, videos, articles, and more.

          Related instruments and applications

          • EVOS Cell Imaging Systems
          • Live cell imaging
          • Fixed cell imaging
          • Immunofluorescence imaging
          • Microscope calibration

          Cell Analysis Support Center
          Find tips, troubleshooting help, and resources for your cell analysis workflow.

          5 Steps resources

          • 5 Steps to Publication-Quality Fixed Cell Imaging
          • 5 Steps to Live-Cell Imaging
          • See all 5 Steps Workflows

          For Research Use Only. Not for use in diagnostic procedures.

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