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Cell Structure
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Organelle structures play a critical role in cellular function, and the detection of specific cell structures is key in fluorescence imaging of cells and tissue. Cell structure labels can be a counterstain method to identify the location of specific proteins and targets of interest within the cell. Our cell labels include cell structure specific dyes or antibodies for live-cell or fixed-cell imaging, as well as for flow cytometry.
Cytoskeleton Structure
Actin, tubulin, and talin stains and fluorescent proteins for use in live or fixed cells.
Learn about phalloidin staining
Endoplasmic Reticulum Structure
Cell-permeant or fluorescent fusion proteins that bind the ER in live cells.
Endosome Structure
Fluorescent fusion proteins that target early or late endosomes in live cells.
Golgi Apparatus Structure
Cell labels that target Golgi lipids or fluorescent proteins that target a Golgi enzyme in live cells.
Lysosome Structure
Live cell markers to target and track acidic organelles or fluorescent proteins that bind the lysosome membrane.
Mitochondria Structure
Cell labels based on mitochondria membrane potential or fluorescent proteins for use in live cells.
Nucleus Structure
Cell-permeant and cell-impermeant stains for the nucleus, nuclear components, and nucleolus.
Peroxisome Structure
Fluorescent proteins for live cells or antibodies for staining peroxisomes in fixed cells.
Plasma Membrane Structure
WGA conjugates, cell membrane stains, and fluorescent fusion proteins for staining cell membranes.
The Image-iT Cell Painting Kit contains six fluorescent dyes. When combined and analyzed on a high-content imager, the software identifies each stained cell and measures ∼1,500 morphological features.
Thermo Fisher Scientific offers an extensive portfolio of highly purified and specific fluorescently conjugated lectins. These lectins come in a variety of dyes including bright Alexa Fluor Dyes, Dylight Dyes, and other classic dyes, to provide bright and sharp images of cells for specific glycoprotein detection. Fluorescent conjugation allows you to easily localize and detect cell-surface or intracellular glycoproteins, making them a versatile primary detection approach for imaging or flow cytometry applications.
CellLight fusion proteins provide an easy way to label specific structures in live cells with fluorescent proteins. Simply add the reagent to your cells, incubate overnight, and you’re ready to image in the morning. These ready-to-use constructs express fluorescent fusion proteins targeted to specific intracellular structures. The fluorescent protein is introduced using a simple transfection step that doesn’t require molecular biology techniques to carry out—it works like a cell stain.
Resources
Molecular Probes Handbook
BioProbes 70 Journal article
Research tools
Cell Structure Information
Find educational resources such as application notes, webinars, videos, articles, and more.
Related instruments and applications
Cell Analysis Support Center
Find tips, troubleshooting help, and resources for your cell analysis workflow.
5 Steps resources
For Research Use Only. Not for use in diagnostic procedures.