The steady-state maintenance of highly asymmetric concentrations of inorganic cations and anions is a feature of living cells. Homeostatic regulation of these ionic gradients is critical for most cellular functions, and measuring ionic concentrations with both spatial and temporal resolution has become critical in research ranging from drug discovery to studies of neuronal function.

We’ve developed a number of Molecular Probes® ion indicators to track calcium and other ion concentrations with intense fluorescent signals and a range of wavelength options.

Ion indicators-Confocal imaging of calcium wave propagation 
Confocal imaging of calcium wave propagation in a HeLa cell. Images were acquired every 200 ms.