High Content Analysis Instruments Citations

HCA cited in peer-reviewed journals

Thermo Scientific high-content analysis instruments are cited extensively in reputable publications. HCA instrument citations in peer-reviewed publications are displayed here. HCA comprises a powerful combination of fluorescence microscopy, image processing, automated cellular measurements, and informatics tools that has enabled fundamental discoveries in basic research—and progression in drug compound discovery. See how researchers like you are using Thermo Scientific CellInsight High-Content Screening (HCS) Platforms to publish their results. Choose a section from one of the tabs below.

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ApplicationTitleSourceYear
cancer, neuroscience, stem cells, virologyCommentary on, “Generation of Three-dimensional Human Neuronal Cultures: Application to Modeling CNS Viral Infections”Journal of Infectiology2019
cancer, neuroscienceCompetitive inhibition by NAG-1/GDF-15 NLS peptide enhances its anti-cancer activityBiochem Biophys Res Commun2019
cancer, immunotherapyDevelopment of in vitro immune effector function assays to better approximate the in vivo behavior of biotherapeutics and cell therapiesJournal for ImmunoTherapy of Cancer2019
cancer, neuroscience, stem cellsEffects of hypoxia and ASIC3 on nucleus pulposus cells: from cell behavior to molecular mechanismBiomedicine & Pharmacotherapy2019
cancer, neuroscience, stem cells, organoidsReview of high-content screening applications in toxicologyArchives of Toxicology2019
cancer, neuroscience, stem cells, organoidsShedding light on microRNA function via microscopy-based screeningMethods2019
stem cellsThalidomide Inhibits Human iPSC Mesendoderm Differentiation by Modulating CRBN-dependent Degradation of SALL4Scientific Reports2020
cancer, neuroscienceHigh-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activitiesCell Biol Toxicol2021
cancer, stem cells, 2D vs 3DMED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgenPLoS Genetics2021
cancerTrans-chalcone suppresses tumor growth mediated at least in part by the induction of heme oxygenase-1 in breast cancerToxicol Res2021
cancer, virologyA Novel Imaging Approach for Single-Cell Real-Time Analysis of Oncolytic Virus Replication and Efficacy in Cancer CellsHum Gene Ther2021
cancerThe Overexpression of Keratin 23 Promotes Migration of Ovarian Cancer via Epithelial-Mesenchymal TransitionBiomed Res Int2020
cancerDisruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic StressInt J Mol Sci2021
cancerType I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosolPLoS Pathogens2021
cancer, stem cells, 2D vs 3D, neuroscienceDefective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndromeNature Communications2021
cancer, 2D vs 3DDefining super-enhancer landscape in triple-negative breast cancer by multiomic profilingNature Communications2021
cancerKEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung CancerCancers2021
immunocompetentDevelopment of an Advanced Multicellular Intestinal Model for Assessing Immunomodulatory Properties of Anti-Inflammatory CompoundsFront Pharmacol2021
neuroscienceInhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in miceCommunications Biology2021
stem cells, 2D Dopamine Levels Induced by Substance Abuse Alter Efficacy of Maraviroc and Expression of CCR5 Conformations on Myeloid Cells: Implications for NeuroHIVFront Immunol2021
immunostainingCryoprecipitate attenuates the endotheliopathy of trauma in mice subjected to hemorrhagic shock and traumaJ Trauma Acute Care Surg2021
cancerAnticancer Effects of Cold Atmospheric Plasma in Canine Osteosarcoma CellsInt J Mol Sci2020
cancer, immunohistochemistryImmune contexture analysis in immuno-oncology: applications and challenges of multiplex fluorescent immunohistochemistryClin Transl Immunology2020
immunoblotsA non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5αPLoS Pathogens2020
cancer, stem cells, neurosurgeryA cell-penetrating MARCKS mimetic selectively triggers cytolytic death in glioblastomaOncogene2020
cancer, stem cellsMuscle Stem Cell-Derived Extracellular Vesicles Reverse Hydrogen Peroxide-Induced Mitochondrial Dysfunction in Mouse MyotubesCells2020
stem cells, 2D vs 3DHuman iNSC-derived brain organoid model of lysosomal storage disorder in Niemann–Pick disease type CCell Death and Disease2020

No records were found matching your criteria

ApplicationTitleSourceYear
cancer, neuroscienceA combined cellomics and proteomics approach to uncover neuronal pathways to psychiatric disorderNeuroproteomics2019
cancerA lung/liver-on-a-chip platform for acute and chronic toxicity studiesLab on a Chip2018
cancer, immunotherapy, neuroscience, stem cellsA Novel Three-Dimensional Glioma Blood-Brain Barrier Model for High-Throughput Testing of Tumoricidal CapabilityFrontiers in Oncology2019
cancer, immunotherapyA novel three-dimensional immune oncology model for high-throughput testing of tumoricidal activityFrontiers in Immunology2018
cancerA simple pyramid-shaped microchamber towards highly efficient isolation of circulating tumor cells from breast cancer patientsBiomed Microdevices2018
neuroscienceAnalysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein …Cellular and Molecular Life …2018
cancer, neuroscience, stem cellsAP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9ANature Communication2018
neuroscience, stem cells, virologyAtovaquone inhibits arbovirus replication through the depletion of intracellular nucleotidesJournal of Virology2019
neuroscience, stem cellsBeyond 2D: effects of photobiomodulation in 3D tissue-like systemsJournal of Biomed Opt.2020
cancer, immunotherapyBoosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2DFrontiers in Immunology2020
cancer, immunotherapy, neuroscience, stem cells, virologyCancer exosomes induce tumor innervationNature Communication2018
stem cellsChaperone mediated detection of small molecule target binding in cellsNature Communication2020
cancerDDIT4 promotes gastric cancer proliferation and tumorigenesis through the p53 and MAPK pathwaysCancer Communication2018
cancerDevelopment of a FRET-Based Assay for Analysis of mAbs Internalization and Processing by Dendritic Cells in Preclinical Immunogenicity Risk AssessmentThe AAPS Journal2020
cancer, neuroscienceDopamine increases HIV entry into macrophages by increasing calcium release via an alternative signaling pathwayBrain, Behavior, and Immunology2019
virologyEvolution-driven attenuation of alphaviruses highlights key glycoprotein determinants regulating viral infectivity and disseminationCell Reports2019
stem cellsExtension of maximal lifespan and high bone marrow chimerism after nonmyeloablative syngeneic transplantation of bone marrow from young to old MiceFrontiers in Genetics2019
 General staining and segmentation procedures for high content imaging and analysisMethods Mol Biol2018
cancer, neuroscience, stem cells, organoidsGeneration of three-dimensional human neuronal cultures: application to modeling CNS viral infectionsStem Cell Research 2018
cancer, neuroscienceGranulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathologyActa Neuropathol2019
cancer, neuroscienceHigh content screening for drug discovery from traditional Chinese medicineChinese medicine2019
cancer, neuroscienceHigh levels of PIWI‐interacting RNAs are present in the small RNA landscape of prostate epithelium from vitamin D clinical trial specimensThe Prostate2019
cancer, virologyHigh-Content Screening, a Reliable System for Coxiella burnetii Isolation from Clinical SamplesJournal of Clinical Microbiol2020
cancer, neuroscienceHigh-Throughput Fluorescence Assays for Ion Channels and GPCRsAdv Exp Med Biol2020
virologyHigh-throughput isolation of giant viruses using high-content screeningCommunications Biology2019
 In Vitro High-Content Imaging-Based Phenotypic Analysis of Bronchial 3D Organotypic Air–Liquid Interface CulturesSLAS2020
cancer, neuroscience, stem cellsIn vitro screening platforms for identifying autophagy modulators in mammalian cellsAutophagy2019
neuroscienceInhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complexJ Cell Sci2018
cancer, neuroscienceIsoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scopariusJournal Asian Nat Prod Res2019
cancer, neuroscienceMARCKS regulates neuritogenesis and interacts with a CDC42 signaling networkScientific reports2018
neuroscience, stem cells, organoidsModeling Leigh syndrome using patient-specific induced pluripotent stem cellsOsaka City Med J2019
 Modular, defined assembly of antibody-based constructs using click chemistryKeystone Symposia2018
neuroscienceModulation of CRMP2 via (S)-Lacosamide shows therapeutic promise but is ultimately ineffective in a mouse model of CLN6-Batten diseaseHealth Psychol Behav Med2019
cancer, neuroscienceNew insights into mechanism of bisphenol analogue neurotoxicity: implications of inhibition of O-GlcNAcase activity in PC12 cellsArchives of Toxicology2019
cancer, neuroscienceNo evidence for cell‐to‐cell transmission of the unfolded protein response in cell cultureJournal of Neurochem2019
cancerNon-Toxic and Ultra-Small Biosilver Nanoclusters Trigger Apoptotic Cell Death in Fluconazole-Resistant Candida albicans via Ras SignalingBiomolecules2019
cancer, neuroscienceOPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretionJournal of Cell Science2020
neuroscience, stem cellsPartial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neuronsEuropean Journal of Neuroscience2019
cancer, neurosciencePhosphorylation of syntaxin 17 by TBK1 controls autophagy initiationDevelopmental Cell2019
cancer, neuroscience, stem cellsPopulation-based analysis of BAP1 germline variations in patients with uveal melanomaHuman Molecular Genetics2019
cancer, immunotherapy, stem cells, organoidsReplication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironmenteLife2019
cancer, neuroscience, stem cells, organoidsReview of high-content screening applications in toxicologyArchives of Toxicology2019
neuroscienceRole of the AP-5 adaptor protein complex in late endosome-to-Golgi retrievalPLoS Biol2018
cancer, neuroscience, stem cells, organoidsShedding light on microRNA function via microscopy-based screeningMethods2019
 Super-multiplexed fluorescence microscopy via photostability contrastBiomedical optics 2018
stem cellsthalidomide inhibits Human ipSc Mesendoderm Differentiation by Modulating cRBn-dependent Degradation of SALL4Scientific Reports2020
cancer, virologyThe ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon responsePLoS Pathog2019
 The WDR11 complex facilitates the tethering of AP-1-derived vesiclesNature Communication2018
cancerTools to measure autophagy using high content imaging and analysisMethods Mol Biol2018
cancer, neuroscienceUnconventional secretion factor GRASP55 is increased by pharmacological unfolded protein response inducers in neuronsScientific Reports2019
cancerVitamin D regulates prostate cell metabolism via genomic and non-genomic mitochondrial redox-dependent mechanismsThe Journal of Steroid Biochemistry and Molecular …2019
cancer, immunotherapyWedge-shaped microfluidic chip for circulating tumor cells isolation and its clinical significance in gastric cancerJournal Transl Med2018
cancer, 2D vs 3D, COVID, coronavirus, stem cellsHigh-content siRNA 3D co-cultures to identify myoepithelial cell-derived breast cancer suppressor proteinsScientific Data2021
cancer, stem cells, virology, coronavirus High-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activitiesCell Biol Toxicol2021
cancer, 2D vs 3DA Novel Imaging Approach for Single-Cell Real-Time Analysis of Oncolytic Virus Replication and Efficacy in Cancer CellsHum Gene Ther2021
cancerKEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung CancerCancers (Basel) 2021
COVID, coronavirus, virologyThe SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airwaysPLoS Pathogens2021
cancer, 2D vs 3DPreclinical Evaluation of Artesunate as an Antineoplastic Agent in Ovarian Cancer Treatment.Diagnostics (Basel)2021

No records were found matching your criteria

ApplicationTitleSourceYear
virologyA Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral EntryMolecular Biology of the Cell2018
neuroscienceA novel inhibitor of inducible NOS dimerization protects against cytokine‐induced rat beta cell dysfunctionBr J Pharmacol2018
virologyA novel piperazine-based drug lead for cryptosporidiosis from the medicines for malaria venture open-access malaria boxAntimicrob Agents Chemother2018
cancer, neuroscienceActivated heterotrimeric G protein αi subunits inhibit Rap-dependent cell adhesion and promote cell migrationJ Biol Chem2018
cancer, immunotherapyADME/toxicity prediction and antitumor activity of novel nitrogenous heterocyclic compounds designed by computer targeting of alkylglycerone phosphate …Oncol Lett2020
stem cellsAdvances in antiwolbachial drug discovery for treatment of parasitic filarial worm infectionsTrop Med Infect Dis2020
cancer, neuroscienceAnalysis of Gene Expression and Neuronal Phenotype in Neuroscreen-1 (NS-1) CellsInt J Biomed Investig2019
cancerBifunctional Au-templated RNA nanoparticles enable direct cell uptake detection and GRP75 knockdown in prostate cancerJ Mater Chem B2018
neuroscience, stem cells, virologyC9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transportSci Rep2019
immunotherapy, virologyConvergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus NeutralizationCell2018
immunotherapy, virologyDesign and evaluation of bi-and trispecific antibodies targeting multiple filovirus glycoproteinsJ Biol Chem2019
neuroscience, stem cellsDifferential effects of glucose deprivation on the survival of fetal versus adult neural stem cells‐derived oligodendrocyte precursor cellsGlia2018
 DMN-Tre Labeling for Detection and High-Content Screening of Compounds against Intracellular MycobacteriaACS Omega2018
cancerDownregulation of MicroRNA-4463 Attenuates High-Glucose-and Hypoxia-Induced Endothelial Cell Injury by Targeting PNUTSCell Physiol Biochem2019
cancer, organoidseIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinomaNature Communication2018
cancerEnhanced cancer theranostics with self-assembled, multilabeled siRNAsACS Omega2019
virologyFloxed-cassette allelic exchange mutagenesis enables markerless gene deletion in Chlamydia trachomatis and can reverse cassette-induced polar effectsJ Bacteriol2020
cancer, virologyFluorescently Labeled siRNAs and their Theranostic Applications in Cancer Gene TherapyACS Omega2018
neuroscience, stem cells, virologyFUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteinsHum Mol Genet2018
cancer, stem cellsGenome-Wide Association Study of Diabetogenic Adipose Morphology in the GENetics of Adipocyte Lipolysis (GENiAL) CohortCells2020
cancer, stem cellsGlucocorticoids delay RAF-induced senescence promoted by EGR1J Cell Sci2018
cancer, stem cellsGlutamine Links Obesity to Inflammation in Human White Adipose TissueCell Metabolism2020
cancer, neuroscience, stem cellsGRP78 modulates cell adhesion markers in prostate Cancer and multiple myeloma cell linesBMC Cancer2020
cancer, stem cellsGTPBP4 promotes gastric cancer progression via regulating P53 activityCell Physiol Biochem2019
cancer, virologyHemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human AirwaysJ Virol2019
cancerHerbicidins from Streptomyces sp. CB01388 Showing Anti-Cryptosporidium ActivityJ Nat Prod2019
cancer, neuroscienceHigh content screening for drug discovery from traditional Chinese medicineChin Med2018
 High-Content Screening for Cryptosporidium Drug DiscoveryMethods Mol Biol2019
cancerHighly Efficient Isolation of Circulating Tumor Cells Using a Simple Wedge-Shaped Microfluidic DeviceIEEE Trans Biomed Eng2019
immunotherapy, virologyHuman monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteinsPLoS Pathog2019
cancer, stem cellsHuman-specific function of IL-10 in adipose tissue linked to insulin resistanceJ Clin Endocrinol Metab2019
cancer, neuroscience, stem cellsIn vitro screening platforms for identifying autophagy modulators in mammalian cellsMethods Mol Biol2020
cancer, neuroscienceKnockdown siRNA targeting the mitochondrial sodium-calcium exchanger-1 inhibits the protective effects of two cannabinoids against acute paclitaxel toxicityJ Mol Neurosci2020
cancer, neuroscience, stem cellsMANF ablation causes prolonged activation of the UPR without neurodegeneration in the mouse midbrain dopamine systemeNeuro2019
cancerMicroRNA-27a/b-3p and PPARG regulate SCAMP3 through a feed-forward loop during adipogenesisSci Rep2020
cancer, neuroscienceMicroscopy-based automated live cell screening for small molecules that affect ciliationFront Genet2020
cancer, immunotherapy, organoidsModular, defined assembly of antibody-based constructs using click chemistryKeystone Symposia2019
cancer, neuroscienceN-substituted phenylbenzamides of the niclosamide chemotype attenuate obesity related changes in high fat diet fed micePLoS One2018
cancerPITPNA-AS1 abrogates the inhibition of miR-876-5p on WNT5A to facilitate hepatocellular carcinoma progressionCell Death Dis2018
cancer, neuroscience, stem cellsPossible Strategies to Optimize a Biomarker Discovery Approach to Correlate with Neurological Outcome in Patients with Spinal Cord Injury: A Pilot StudyJ Neurotrauma2018
cancer, neuroscience, stem cellsProlactin, Estradiol and Testosterone Differentially Impact Human Hippocampal Neurogenesis in an In Vitro ModelNeuroscience2018
cancer, neuroscienceProtective effect of 3-hydroxybutyrate against endoplasmic reticulum stress-associated vascular endothelial cell damage induced by low glucose exposurePLoS One2018
cancerPumpless platform for high-throughput dynamic multicellular culture and chemosensitivity evaluationLab Chip2019
stem cellsRecombinant extracellular matrix protein fragments support human embryonic stem cell chondrogenesisTissue Eng Part A2019
cancer, stem cells, organoidsShedding light on microRNA function via microscopy-based screeningMethods2018
cancer, immunotherapy, virologyStructural Basis of Broad Ebolavirus Neutralization by a Human Survivor AntibodyNat Struct Mol Biol2019
immunotherapy, stem cells, virologySystematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protectionCell2019
cancerTechniques to Enable 1536-Well Phenotypic ScreeningMethods Mol Biol2019
stem cellsThe microbiota regulates inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelinationPNAS2019
neuroscience, stem cellsThe role of nuclear receptors in the differentiation of oligodendrocyte precursor cells derived from fetal and adult neural stem cellsStem Cell Res2019
stem cells, virologyTHP-1 and Dictyostelium infection models for screening and characterization of anti-Mycobacterium abscessus hit compoundsAntimicrob Agents Chemother2019
cancer, virologyVesicular Stomatitis Virus-Based Vaccines Provide Cross-Protection against Andes and Sin Nombre Viruses.Viruses2019
cancer, stem cellsLoss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decayNature Cell Biology2021
cancer, stem cellsPharmacological Protein Kinase C Modulators Reveal a Pro-hypertrophic Role for Novel Protein Kinase C Isoforms in Human Induced Pluripotent Stem Cell-Derived CardiomyocytesFront Pharmacol2021
cancerTowards the development of safer by design TiO2-based photocatalytic paint: impacts and performancesEnvironmental Science Nano2021
immunology, COVID, coronavirus The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airwaysPLoS Pathogens2021
cancerStabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replicationNPJ Precis Oncol2021
coronavirus, COVIDA single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidateNature 2020
 Inter-Laboratory Reproducibility and Interchangeability of 3R4F and 1R6F Reference Cigarettes in Mainstream Smoke Chemical Analysis and In Vitro Toxicity AssaysSciendo2021
cancer, stem cellsGATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPSC-derived cardiomyocytesArch Toxicol2020
 PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosisAnn Rheum Dis2020
cancer, neurological    Metabolite Profiling, Isolation of Cyclic Polyols, Antioxidant and Anti-inflammatory Activities of Aegle Marmelos: NMR and GC-MS Based Metabolomics StudyJournal of Herbs, Spices, and Medicinal Plants2020
cancer, RNAiHigh-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity Against Mycobacterium tuberculosisFrontiers in Microbiology2020
 Biotransformation of Food-Grade and Nanometric TiO2 in the Oral–Gastro–Intestinal Tract: Driving Forces and Effect on the Toxicity toward Intestinal Epithelial CellsNanomaterials (Basel)2020
COVID, coronavirus, virologyThe SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airwaysPLoS Pathogens2021
cancer stem cells, virologyLoss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decayPLoS Pathogens2021

No records were found matching your criteria

ApplicationTitleSourceYear
cancer, neuroscience, stem cells, organoids, virologyA fluorescent cell-based system for imaging Zika virus infection in real-timeViruses2018
cancerA genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrestNucleic Acids Res2019
stem cellsA head-to-head Caco-2 assay comparison of the mechanisms of action of the intestinal permeation enhancers: SNAC and sodium caprate (C10)European Journal of Pharm Biopharm2020
 A high content screening assay for identifying inhibitors against active and dormant state intracellular Mycobacterium tuberculosisJournal of Microbiological Methods2019
cancer, neuroscienceA Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small MoleculesScientific Reports2020
neuroscienceA Novel RNA editing sensor tool and a specific agonist determine neuronal protein expression of RNA-edited glycine receptors and identify a genomic …Frontiers in Molecular Neuro2018
cancer, stem cellsA novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylationOncotarget2019
cancer, neuroscience, stem cells, organoidsA SMN2 Splicing Modifier Rescues the Disease Phenotypes in an In Vitro Human Spinal Muscular Atrophy ModelStem Cells and Dev2019
cancer, neuroscienceA stress-enhanced model for discovery of disease-modifying gene: Ece1-suppresses the toxicity of α-synuclein A30PNeurobiology of Disease2018
cancer, stem cellsA β1-tubulin–based megakaryocyte maturation reporter system identifies novel drugs that promote platelet productionBlood Adv2018
cancer, neuroscienceActivation of Nrf2 signaling by salvianolic acid C attenuates NF‑κB mediated inflammatory response both in vivo and in vitroInt Immunopharmacol2018
cancer, virologyAdvanced identification of global bioactivity hotspots via screening of the metabolic fingerprint of entire ecosystemsScientific Reports2020
cancer, immunotherapy, stem cellsAdvanced Materials and Devices for the Regulation and Study of NK CellsInternational Journal of Molecular Sciences2019
cancerAMMECR1 Inhibits Apoptosis and Promotes Cell-cycle Progression and Proliferation of the A549 Human Lung Cancer Cell LineAnticancer Res2019
neuroscience, stem cellsAn analog derived from phenylpropanoids ameliorates Alzheimer's disease–like pathology and protects mitochondrial functionNeurobiology of Aging2019
cancer, stem cellsAn endothelial cell/mesenchymal stem cell coculture cord formation assay to model vascular biology in vitro

 

Methods Mol Biol

2018
 Analysis and quantification of oxidized low-density lipoprotein-induced lipid droplets in macrophages through high-content screening: Application for antiatherogenic …Assay and Drug Development Technologies2019
 Andrographolide protects chondrocytes from oxidative stress injury by activation of the Keap1–Nrf2–Are signaling pathwayJ Cell Physiol2019
cancerAnlotinib inhibits synovial sarcoma by targeting GINS1: a novel downstream target oncogene in progression of synovial sarcomaClinical and Translational Oncology2019
cancer, immunotherapy, neuroscienceAntibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomesScientific Reports2019
cancer, immunotherapyAnticancer Activity of Earthworm Powder (Lumbricus terrestris) Against MCF-7 and PC-3 Cancer Cell LinesJournal of Gastrointestinal Cancer2019
 Anti-inflammatory activity of dehydroandrographolide by TLR4/NF-κB signaling pathway inhibition in bile duct-ligated miceCell Physiol Biochem2018
cancer, neuroscienceAnti-inflammatory effects and mechanism of the total flavonoids from Artemisia scoparia Waldst. et kit. in vitro and in vivoBiomed Pharmacother2018
cancer, stem cellsArrayed functional genetic screenings in pluripotency reprogramming and differentiationStem Cell Research & Therapy2019
stem cellsAryl hydrocarbon receptor modulation by tuberculosis drugs impairs host defense and treatment outcomesCell Host & Microbe2020
cancerAssessment of novel tobacco heating product THP1. 0. Part 6: a comparative in vitro study using contemporary screening approachesRegul Toxicol Pharmacol2018
cancerATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failureGenetic Med2019
cancerAutomated Detection of Autophagy Response Using Single Cell-Based Microscopy AssaysAutophagy2019
cancer, neuroscience, stem cellsAutophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertensionJ Pathology2019
cancer, immunotherapy, stem cellsB591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cellsOncogene2019
cancerBAI1‑associated protein 2‑like 2 is a potential biomarker in lung cancerOncology Report2019
cancer, neuroscience, stem cellsBCL2 and BCL (X) L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2 …Oncotarget2018
neuroscienceBenzalkonium chloride-induced direct and indirect toxicity on corneal epithelial and trigeminal neuronal cells: proinflammatory and apoptotic responses in vitroToxicology letters2020
cancer, neuroscienceBioinspired Honokiol Analogs and Their Evaluation for Activity on the Norepinephrine TransporterMolecules2018
neuroscienceBlue light exposure in vitro causes toxicity to trigeminal neurons and glia through increased superoxide and hydrogen peroxide generationFree Radic Biol Med2019
 Breast Milk and Saliva Lactoferrin Levels and Postnatal Cytomegalovirus InfectionAm J Perinatol2020
cancer, stem cellsCardiac Toxicity From Ethanol Exposure in Human-Induced Pluripotent Stem Cell-Derived CardiomyocytesToxicol Sci2019
cancer, immunotherapyCasein Kinase 2 Interacting Protein-1 Suppresses Glioma Cell Proliferation via Regulating the AKT/GSK3/-Catenin PathwayBiomed Res Int2019
cancer, stem cellsCell-Based High Content Analysis of Cell Proliferation and ApoptosisHigh Content Screening2018
cancer, neuroscienceCell‐based high‐throughput screen for small molecule inhibitors of Bax translocationJ Cell Mol Med2019
cancerCellular fluorescein hyperfluorescence is dynamin-dependent and increased by Tetronic 1107 treatmentInt J Biochem Cell Biol2018
cancerChlamydia trachomatis fails to protect its growth niche against pro-apoptotic insultsCell Death Differ2019
cancerChloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusionAutophagy2018
cancer, immunotherapyCIZ1 knockdown suppresses the proliferation of bladder cancer cells by inducing apoptosisGene2019
cancerCombined PPARγ activation and XIAP inhibition as a potential therapeutic strategy for ovarian granulosa cell tumorsMol Cancer Therap2019
cancer, stem cells, virologyCompounds producing an effective combinatorial regimen for disruption of HIV‐1 latencyEMBO Mol Med2018
cancerConjugate Polyplexes with Anti-Invasive Properties and Improved siRNA Delivery In VivoBioconjugate Chemistry2018
cancer, neuroscience, stem cells, organoidsConstitutive Activity of a G Protein‐Coupled Receptor, DRD1, Contributes to Human Cerebral Organoid FormationSTEM CELLS2020
cancer, neuroscienceCoQ10 ameliorates mitochondrial dysfunction in diabetic nephropathy through mitophagyJ Endocrinol 
cancer, neuroscienceCyclin-dependent kinase 18 controls trafficking of aquaporin-2 and its abundance through ubiquitin ligase STUB1, which functions as an AKAPCells2020
cancerCyclodextrin-and dendrimer-conjugated graphene oxide as a nanocarrier for the delivery of selected chemotherapeutic and photosensitizing agentsMater Sci Eng C Mater Biol Appl2018
cancer, neuroscience, stem cellsCytotoxic Mechanism for Silver Nanoparticles Based High-Content Cellomics and Transcriptome SequencingJ Biomed Nanotechnol2019
cancerDelivery of miR-146a to Ly6Chigh monocytes inhibits pathogenic bone erosion in inflammatory arthritisTheranostics2018
cancer, neuroscience, stem cellsDetection of Rare Objects by Flow Cytometry: Imaging, Cell Sorting, and Deep Learning ApproachesIntl J Mol Science2020
cancerDevelopment and application of high-content biological screening for modulators of NET productionFrontiers in Immunol2018
 Development and optimization of a miniaturized western blot-based screening platform to identify regulators of post-translational modificationsHigh-throughput2019
neuroscienceDevelopment of a cell-based assay to assess binding of the proNGF prodomain to sortilinCell Mol Neuro 2018
cancer, immunotherapy, stem cells, virologyDevelopment of a novel screening platform for the identification of small molecule inhibitors of human adenovirusVirology2019
cancer, neuroscience, stem cellsDevelopment of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of DrugsNeuroscience Bull2019
cancerDiazinon exposure activated transcriptional factors CCAAT-enhancer-binding proteins α (C/EBPα) and peroxisome proliferator-activated receptor γ (PPARγ) and …Pesticide Biochemistry and Physiology2018
 Differentiated mitochondrial function in mouse 3T3 fibroblasts and human epithelial or endothelial cells in response to chemical exposureBasic Clin Pharmacol Toxicol2019
cancerDifferentiation of Aneugens and Clastogens in the In Vitro Micronucleus Test by Kinetochore Scoring Using Automated Image AnalysisEnviron Mol Mutagen2019
neuroscienceDirect, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit α 2 δ-1 with thrombospondin-4Scientific Reports2019
cancerDiscovery of the first potent, selective, and orally bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) inhibitor displaying pronounced immunomodulatory effects …J Med Chem2018
cancerDiscovery of the Polyamine Conjugate with Benzo[cd]indol-2(1H)-one as a Lysosome-Targeted Antimetastatic AgentJ Med Chem2018
cancer, neuroscienceDownregulation of CPA4 inhibits non small–cell lung cancer growth by suppressing the AKT/c‐MYC pathwayMol Carcinogen2019
cancerDownregulation of RNA binding motif protein 17 expression inhibits proliferation of hypopharyngeal carcinoma FaDu cellsOncology2018
cancer, neuroscienceDownregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent …Cancer Biol Med2020
cancer, immunotherapy, neuroscienceDrug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeuticsMed Res Rev2020
virologyDual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesisScientific reports2019
cancer, neuroscience, stem cells, organoidsDYRK1A Is a Regulator of S-Phase Entry in Hepatic Progenitor CellsStem Cells Dev2018
 Elevated transforming growth factor β signaling activation in β‐actin‐knockout mouse embryonic fibroblasts enhances myofibroblast featuresJournal of cellular physiology2018
cancerElongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome StabilityMolecular cell2019
virologyEndophilin-A2-mediated endocytic pathway is critical for enterovirus 71 entry into caco-2 cellsEmerging microbes & …2019
cancerEndoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytesFree Radic Biol Med2018
 Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatmentScientific reports2018
cancerExploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathwayJ Bone Oncol2019
cancer, immunotherapyExtracellular DNA promotes colorectal tumor cell survival after cytotoxic chemotherapyJ Surg Res2018
cancer, stem cellsExtracellular vesicles induce minimal hepatotoxicity and immunogenicityNanoscale2019
cancerFunctional characterization of glucocorticoid receptor variants is required to avoid misinterpretation of NGS dataJ Endocr Soc2019
cancerFunctional Comparison of XPF Missense Mutations Associated to Multiple DNA Repair DisordersGenes2019
virologyFunctional insights into the adjacent stem-loop in honey bee dicistroviruses that promotes internal ribosome entry site-mediated translation and viral infectionJournal of virology2018
cancerFunctional regulation of human trophoblast cells by CSE1LJ Matern Fetal Neonatal Med2019
 Fuzhenghuayu Decoction ameliorates hepatic fibrosis by attenuating experimental sinusoidal capillarization and liver angiogenesisScientific Reports2019
neuroscience, stem cellsFZD4 marks lateral plate mesoderm and signals with NORRIN to increase cardiomyocyte induction from pluripotent stem cell-derived cardiac progenitorsStem Cell Reports2018
cancer, neuroscience, stem cellsGenes and pathways regulated by androgens in human neural cells, potential candidates for the male excess in autism spectrum disorderBiol Psychiatry2018
cancer, stem cellsGenetic and chemical screenings identify HDAC3 as a key regulator in hepatic differentiation of human pluripotent stem cellsStem Cell Reports2018
cancerGlutathione accelerates osteoclast differentiation and inflammatory bone destructionFree Radical Res2019
cancer, stem cellsGlycylglycine plays critical roles in the proliferation of spermatogonial stem cellsMolecular Med Rep2019
neuroscienceGPR146 Deficiency Protects against Hypercholesterolemia and AtherosclerosisCell2019
cancerHigh content imaging assays for IL-6-induced STAT3 pathway activation in head and neck cancer cell linesMethod Mol Bio2018
cancer, virologyHigh content positional biosensor assay to screen for compounds that prevent or disrupt androgen receptor and transcription intermediary factor 2 protein-protein …Method Mol Bio2018
cancer, neuroscienceHigh content screening in NHBE cells shows significantly reduced biological activity of flavoured e-liquids, when compared to cigarette smoke condensateToxicology in Vitro2019
cancer, stem cellsHigh content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastomaPloS One2018
cancer, neuroscienceHigh glucose triggers nucleotide imbalance through O-GlcNAcylation of key enzymes and induces KRAS mutation in pancreatic cellsCell Metabolism2019
cancer, neuroscienceHigh-Content Imaging of Immunofluorescently Labeled TRPV1-Positive Sensory NeuronsMethod Mol Bio2019
stem cells, organoidsHigh-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targetsJournal of Molecular and Cell Cardiol2019
neuroscience, stem cellsHigh‐throughput identification of factors promoting neuronal differentiation of human neural progenitor cells in microscale 3D cell cultureBiotechnology and Bioeng2019
cancer, neuroscience, stem cellsHost-targeted niclosamide inhibits C. difficile virulence and prevents disease in mice without disrupting the gut microbiotaNat Commun2018
cancer, immunotherapy, neuroscienceHuman corticotrophin releasing factor inhibits cell proliferation and promotes apoptosis through upregulation of tumor protein p53 in human gliomaOncology Letters2018
stem cellsHuman pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesisNat Commun2019
cancer, neuroscience, stem cellsHuman-derived neurons and neural progenitor cells in high content imaging applicationsMethod Mol Bio2018
 Identification and analyses of inhibitors targeting apolipoprotein (a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain functionJournal of Biological Chemistry2020
cancerIdentification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME ScreenAutophagy2019
neuroscience, stem cellsIdentification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neuronsEur J Med Chem2019
cancer, neuroscience, virologyIdentification of Hsp90 inhibitors with anti-Plasmodium activityAntimicrobial Agents Chemotherapy2018
stem cellsIn vivo expansion of functional human hematopoietic stem progenitor cells by butyzamideInternational Journal of Hematology2020
cancer, stem cellsIn-depth proteome analysis highlights HepaRG cells as a versatile cell system surrogate for primary human hepatocytesCells2019
cancer, neuroscienceInduction of migration of periodontal ligament cells by selective regulation of integrin subunitsJournal of Cellular Mol Med2019
cancer, neuroscienceInflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell deathNeurobiology of Disease2018
cancer, stem cellsInhibition of human prostate cancer (PC-3) cells and targeting of PC-3-derived prostate cancer stem cells with koenimbin, a natural dietary compound from …Drug Design Devel Ther2018
cancer, neuroscienceInhibition of myostatin signal pathway may be involved in low-intensity pulsed ultrasound promoting bone healingJournal of Medical Ultrason2019
cancerInhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo-and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation StatusCancers2019
neuroscienceInhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complexJ Cell Sci2018
cancer, neuroscienceInhibition of the MID1 protein complex: a novel approach targeting APP protein synthesisCell Death Discovery2018
virologyIntegrative analysis of Zika virus genome RNA structure reveals critical determinants of viral infectivityCell Host & Microbe2018
 Interaction of mycobacteria with Plasmin (ogen) affects phagocytosis and granuloma developmentTuberculosis2019
neuroscience, virologyInterferon-induced transmembrane protein 1 restricts replication of viruses that enter cells via the plasma membraneJournal of Virology2019
cancerKIAA0101 inhibition suppresses cell proliferation and cell cycle progression by promoting the interaction between p53 and Sp1 in breast cancerBiochemical and Biophysical Research 2018
cancer, stem cellsKLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the boneOncogene2019
cancerKnockdown expression of MECR, a novel gene of mitochondrial FAS II inhibits growth and colony-formation, promotes apoptosis of hepatocellular carcinoma cellsBioscience Trends2019
cancerKnockdown of CCNO decreases the tumorigenicity of gastric cancer by inducing apoptosisOncoTargets and Ther2018
cancer, neuroscienceKnockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expressionBioscience Reports2020
cancerKnockdown of PSMC3IP suppresses the proliferation and xenografted tumorigenesis of hepatocellular carcinoma cellJournal of Cellular Biochem2019
cancer, stem cellsKnockdown of ubiquitin associated protein 2-like (UBAP2L) inhibits growth and metastasis of hepatocellular carcinomaMedical Science Monitor 2018
cancer, immunotherapy, neuroscienceKushenol E inhibits autophagy and impairs lysosomal positioning via VCP/p97 inhibitionBiochemical Pharmacol2020
cancer, neuroscience, stem cellsLack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clustersScientific Reports2018
cancer, virologyLentivirus mediated γ-interferon-inducible lysosomal thiol reductase (GILT) knockdown suppresses human glioma U373MG cell proliferationBiochem Biophys Res Commun2019
cancerLIMD 1 phosphorylation in mitosis is required for mitotic progression and its tumor‐suppressing activityFEBS2019
cancer, neuroscience, virologyLINE-1 protein localization and functional dynamics during the cell cycleElife2018
cancer, neuroscienceLipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic …European Journal of Med Chem2020
 Live-cell measurements of kinase activity in single cells using translocation reportersNature Protocols2018
stem cellsLong-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantationNature2019
virologyMagnitude and diversity of immune response to vaccinia virus is dependent on route of administrationVirology2020
cancerMAT2B expression correlates with poor prognosis in triple-negative breast cancerCancer Management and Research2019
cancer, stem cells, organoidsMDH1 and MPP7 regulate autophagy in pancreatic ductal adenocarcinomaCancer Research2019
cancerMicroRNA-27a controls the intracellular survival of Mycobacterium tuberculosis by regulating calcium-associated autophagyNature Comms2018
cancer, stem cellsMicroscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell linesArchives of Tox2018
cancer, stem cellsmiR-122 release in exosomes precedes overt tolvaptan-induced necrosis in a primary human hepatocyte micropatterned coculture modelToxicological Sci2018
cancer, neurosciencemiR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3–Binding Domain to Regulate Wnt1Molecular Cancer Res2019
 miR-182-3p/Myadm contribute to pulmonary artery hypertension vascular remodeling via a KLF4/p21-dependent mechanismTheranostics2020
cancer, stem cellsmiR-211 sponges lncRNA MALAT1 to suppress tumor growth and progression through inhibiting PHF19 in ovarian carcinomaThe FASEB Journal2018
cancer, neuroscienceMitochondria are transported along microtubules in membrane nanotubes to rescue distressed cardiomyocytes from apoptosisCell Death & Disease2018
cancerMonosomy 18p is a risk factor for facioscapulohumeral dystrophyJournal of Medical Genetics2018
cancer, neuroscienceMTP18 is a Novel Regulator of Mitochondrial Fission in CNS Neuron Development, Axonal Growth, and Injury ResponsesScientific Reports2019
cancerMuscarinic acetylcholine type 1 receptor activity constrains neurite outgrowth by inhibiting microtubule polymerization and mitochondrial trafficking in adult …Frontiers in Neuroscience2018
cancer, neuroscienceMuscarinic receptor antagonists activate ERK-CREB signaling to augment neurite outgrowth of adult sensory neuronsNeuropharmacology2018
cancer, stem cellsNaCl nanoparticles as a cancer therapeuticAdvanced Materials2019
cancer, neuroscienceN-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expressionScientific Reports2018
 Nanoscale coupling of endocytic pit growth and stabilityScience Adv2019
cancer, neuroscienceNHE5 regulates growth factor signaling, integrin trafficking, and degradation in glioma cellsClinical & Experimental Metastasis2019
cancer, neuroscience, stem cellsNovel 3D liquid cell culture method for anchorage-independent cell growth, cell imaging and automated drug screeningScientific Reports2018
cancer, neuroscienceNuclear myosin 1 activates p21 gene transcription in response to DNA damage through a chromatin-based mechanismCommunications Biology2020
cancer, virologyOptimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptideeLife2019
cancerPanduratin A induces protective autophagy in melanoma via the AMPK and mTOR pathwayPhytomedicine2018
cancer, neuroscience, stem cellsPer-and polyfluoroalkyl substances impact human spermatogenesis in a stem-cell-derived modelSystems Biology in Reprod Med2018
cancer, neuroscience, stem cellsPhenotypic and functional characteristics of human Schwann cells as revealed by cell-based assays and RNA-seqMolecular Neurobiology2018
cancerPlagioneurin B, a potent isolated compound induces apoptotic signalling pathways and cell cycle arrest in ovarian cancer cellsApoptosis2018
cancer, neuroscience, stem cellsPP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemiaScience Translational Med2018
cancer, neurosciencePreclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancerOncotarget2018
 Pro-inflammatory cytokines enhance dilatation of bile canaliculi caused by cholestatic antibioticsToxicology in Vitro2019
cancerProtein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophyJournal of Biological Chemistry2018
cancer, neuroscience, stem cellsProteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout miceHuman Molecular Genetics2018
 Ptr/CTL0175 is required for the efficient recovery of Chlamydia trachomatis from stress induced by gamma-interferonFrontiers in Microbiology2019
cancerPu-erh tea relaxes the thoracic aorta of rats by reducing intracellular calciumFront Pharmacol2019
 Quercetin protect cigarette smoke extracts induced inflammation and apoptosis in RPE cellsArtif Cells Nanomed Biotechnol2019
cancerRBM17 controls apoptosis and proliferation to promote Glioma progressionBiochem Biophys Res Commun2018
cancer, neuroscienceReal-time monitoring of DNA G-quadruplexes in living cells with a small-molecule fluorescent probeNucleic Acids Research2018
cancer, neuroscience, stem cells, organoidsRecent Advances in Microfluidic Techniques for Systems BiologyAnalytical Chemistry2018
cancerRegulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanomaPNAS2019
cancer, neuroscience, stem cellsRepression of somatic genes by selective recruitment of HDAC3 by BLIMP1 is essential for mouse primordial germ cell fate determinationCell Reports2018
cancer, neuroscienceReversine inhibits colon carcinoma cell migration by targeting JNK1Scientific Reports2018
cancerRole of miR‑449b‑3p in endometriosis via effects on endometrial stromal cell proliferation and angiogenesisMolecular Medicine Reports2018
cancer, neuroscienceRPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availabilityNature Cell Biology2019
cancer, neuroscienceSevere PATCHED1 deficiency in cancer-prone Gorlin patient cells results in intrinsic radiosensitivityInt J Radiat Oncol Biol Phys2018
cancer, neuroscienceSoluble laminin polymers enhance axon growth of primary neurons in vitroJournal of Biomedical Chemistry2018
neuroscienceSpecific Knockdown of α-Synuclein by Peptide-Directed Proteasome Degradation Rescued Its Associated NeurotoxicityCell Chemical2020
cancerSpontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV IntegrinsNephron2019
cancerStable Redox-Cycling Nitroxide Tempol Has Antifungal and Immune-Modulatory PropertiesFrontiers in Microbiology2019
cancerStaphylococcus aureus induces DNA damage in host cellScientific Reports2019
cancer, neuroscienceStructural analysis and cellular visualization of APP RNA G-quadruplexChemical Science2019
stem cellsSuppression of adipocyte differentiation by low‐intensity pulsed ultrasound via inhibition of insulin signaling and promotion of CCN family protein 2Journal of Cellular Biochem2020
cancerSuppression of CCT3 inhibits malignant proliferation of human papillary thyroid carcinoma cellOncology Letters2018
cancerSynthesis and evaluation of 1, 3, 4-oxadiazole derivatives for development as broad-spectrum antibioticsBioorganic & Medicinal Chem2019
cancer, neuroscienceSynthetic probe development for measuring single or few-cell activity and effluxMethods in Enzymology2019
 Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cellsToxicology Reports2020
neuroscience, stem cells, organoidsTesting for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopmentToxicology and Applied Pharmcol2018
cancerTFIIA transcriptional activity is controlled by a 'cleave-and-run'Exportin-1/Taspase 1-switchJournal of Molecular Cell Bio2018
cancerTGFβ promotes genomic instability after loss of RUNX3Cancer Research2018
stem cellsthalidomide inhibits Human ipSc Mesendoderm Differentiation by Modulating cRBn-dependent Degradation of SALL4Scientific Reports2020
cancer, neuroscience, stem cellsThe AMPK/p27Kip1 axis regulates autophagy/apoptosis decisions in aged skeletal muscle stem cellsStem Cell Reports2018
cancerThe antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418PloS One2019
cancer, neuroscienceThe biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco productToxicology in Vitro2018
cancer, stem cellsThe Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor SuppressionCell Reports2018
cancer, neuroscience, stem cellsThe dynamics of TGF-β signaling are dictated by receptor trafficking via the ESCRT machineryCell Reports2018
cancer, neuroscienceThe effect of Jun dimerization on neurite outgrowth and motif bindingMolecular and Cellular Neuroscience2018
cancerThe glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinomaOncogene2018
cancerThe lead optimization of the polyamine conjugate of flavonoid with a naphthalene motif: Synthesis and biological evaluationEuropean Journal of Med Chem2018
cancer, neuroscienceThe relative composition of actin isoforms regulates cell surface biophysical features and cellular behaviorsBiochimica et Biophysica 2018
 The secreted protein kinase CstK from Coxiella burnetii influences vacuole development and interacts with the GTPase-activating host protein TBC1D5Journal of Biological Chemistry2020
cancerThe tetrahydroxanthone-dimer phomoxanthone A is a strong inducer of apoptosis in cisplatin-resistant solid cancer cellsBioorganic & Medicinal  Chemistry2019
neuroscience, stem cellsTilianin mediates neuroprotection against ischemic injury by attenuating CaMKII-dependent mitochondrion-mediated apoptosis and MAPK/NF-κB signalingLife Sciences2019
cancer, neuroscience, stem cellsTools to measure cell health and cytotoxicity using high content imaging and analysisMethods Mol Biol2018
neuroscience, stem cellsTranscriptomically Guided Mesendoderm Induction of Human Pluripotent Stem Cells Using a Systematically Defined Culture SchemeStem Cell Reports2019
virologyTransmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cellsScientific Reports2018
neuroscienceTriclosan Affects Ca2+ Regulatory Module and Musculature Development in Skeletal Myocyte during Early Life Stages of Zebrafish (Danio rerio)Environmental Science & Technology2019
cancerUBE2S promotes the proliferation and survival of human lung adenocarcinoma cellsBMB reports2018
cancer, neuroscienceUBQLN4 represses homologous recombination and is overexpressed in aggressive tumorsCell2019
neuroscienceUnconventional secretion factor GRASP55 is increased by pharmacological unfolded protein response inducers in neuronsScientific Reports2019
cancer, neuroscienceVitegnoside Mitigates Neuronal Injury, Mitochondrial Apoptosis, and Inflammation in an Alzheimer's Disease Cell Model via the p38 MAPK/JNK PathwayJournal of Alzheimer's Dis2019
cancerWee1 inhibitor AZD1775 effectively inhibits the malignant phenotypes of esophageal squamous cell carcinoma in vitro and in vivoFrontiers in Pharmacol2019
cancerYAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodelingJournal of Transl Med2020
cancer, stem cellsYES1 is a targetable oncogene in cancers harboring YES1 gene amplificationCancer Research2019
cancer, neuroscience, stem cellsβ-Actin–dependent global chromatin organization and gene expression programs control cellular identityThe FASEB Journal2018

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ApplicationTitleSourceYear
cancer, neuroscience, stem cells, virologyCommentary on, “Generation of Three-dimensional Human Neuronal Cultures: Application to Modeling CNS Viral Infections”Journal of Infectiology2019
cancer, neuroscienceCompetitive inhibition by NAG-1/GDF-15 NLS peptide enhances its anti-cancer activityBiochem Biophys Res Commun2019
cancer, immunotherapyDevelopment of in vitro immune effector function assays to better approximate the in vivo behavior of biotherapeutics and cell therapiesJournal for ImmunoTherapy of Cancer2019
cancer, neuroscience, stem cellsEffects of hypoxia and ASIC3 on nucleus pulposus cells: from cell behavior to molecular mechanismBiomedicine & Pharmacotherapy2019
cancer, neuroscience, stem cells, organoidsReview of high-content screening applications in toxicologyArchives of Toxicology2019
cancer, neuroscience, stem cells, organoidsShedding light on microRNA function via microscopy-based screeningMethods2019
stem cellsThalidomide Inhibits Human iPSC Mesendoderm Differentiation by Modulating CRBN-dependent Degradation of SALL4Scientific Reports2020
cancer, neuroscienceHigh-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activitiesCell Biol Toxicol2021
cancer, stem cells, 2D vs 3DMED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgenPLoS Genetics2021
cancerTrans-chalcone suppresses tumor growth mediated at least in part by the induction of heme oxygenase-1 in breast cancerToxicol Res2021
cancer, virologyA Novel Imaging Approach for Single-Cell Real-Time Analysis of Oncolytic Virus Replication and Efficacy in Cancer CellsHum Gene Ther2021
cancerThe Overexpression of Keratin 23 Promotes Migration of Ovarian Cancer via Epithelial-Mesenchymal TransitionBiomed Res Int2020
cancerDisruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic StressInt J Mol Sci2021
cancerType I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosolPLoS Pathogens2021
cancer, stem cells, 2D vs 3D, neuroscienceDefective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndromeNature Communications2021
cancer, 2D vs 3DDefining super-enhancer landscape in triple-negative breast cancer by multiomic profilingNature Communications2021
cancerKEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung CancerCancers2021
immunocompetentDevelopment of an Advanced Multicellular Intestinal Model for Assessing Immunomodulatory Properties of Anti-Inflammatory CompoundsFront Pharmacol2021
neuroscienceInhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in miceCommunications Biology2021
stem cells, 2D Dopamine Levels Induced by Substance Abuse Alter Efficacy of Maraviroc and Expression of CCR5 Conformations on Myeloid Cells: Implications for NeuroHIVFront Immunol2021
immunostainingCryoprecipitate attenuates the endotheliopathy of trauma in mice subjected to hemorrhagic shock and traumaJ Trauma Acute Care Surg2021
cancerAnticancer Effects of Cold Atmospheric Plasma in Canine Osteosarcoma CellsInt J Mol Sci2020
cancer, immunohistochemistryImmune contexture analysis in immuno-oncology: applications and challenges of multiplex fluorescent immunohistochemistryClin Transl Immunology2020
immunoblotsA non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5αPLoS Pathogens2020
cancer, stem cells, neurosurgeryA cell-penetrating MARCKS mimetic selectively triggers cytolytic death in glioblastomaOncogene2020
cancer, stem cellsMuscle Stem Cell-Derived Extracellular Vesicles Reverse Hydrogen Peroxide-Induced Mitochondrial Dysfunction in Mouse MyotubesCells2020
stem cells, 2D vs 3DHuman iNSC-derived brain organoid model of lysosomal storage disorder in Niemann–Pick disease type CCell Death and Disease2020

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cancer, neuroscienceA combined cellomics and proteomics approach to uncover neuronal pathways to psychiatric disorderNeuroproteomics2019
cancerA lung/liver-on-a-chip platform for acute and chronic toxicity studiesLab on a Chip2018
cancer, immunotherapy, neuroscience, stem cellsA Novel Three-Dimensional Glioma Blood-Brain Barrier Model for High-Throughput Testing of Tumoricidal CapabilityFrontiers in Oncology2019
cancer, immunotherapyA novel three-dimensional immune oncology model for high-throughput testing of tumoricidal activityFrontiers in Immunology2018
cancerA simple pyramid-shaped microchamber towards highly efficient isolation of circulating tumor cells from breast cancer patientsBiomed Microdevices2018
neuroscienceAnalysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein …Cellular and Molecular Life …2018
cancer, neuroscience, stem cellsAP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9ANature Communication2018
neuroscience, stem cells, virologyAtovaquone inhibits arbovirus replication through the depletion of intracellular nucleotidesJournal of Virology2019
neuroscience, stem cellsBeyond 2D: effects of photobiomodulation in 3D tissue-like systemsJournal of Biomed Opt.2020
cancer, immunotherapyBoosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2DFrontiers in Immunology2020
cancer, immunotherapy, neuroscience, stem cells, virologyCancer exosomes induce tumor innervationNature Communication2018
stem cellsChaperone mediated detection of small molecule target binding in cellsNature Communication2020
cancerDDIT4 promotes gastric cancer proliferation and tumorigenesis through the p53 and MAPK pathwaysCancer Communication2018
cancerDevelopment of a FRET-Based Assay for Analysis of mAbs Internalization and Processing by Dendritic Cells in Preclinical Immunogenicity Risk AssessmentThe AAPS Journal2020
cancer, neuroscienceDopamine increases HIV entry into macrophages by increasing calcium release via an alternative signaling pathwayBrain, Behavior, and Immunology2019
virologyEvolution-driven attenuation of alphaviruses highlights key glycoprotein determinants regulating viral infectivity and disseminationCell Reports2019
stem cellsExtension of maximal lifespan and high bone marrow chimerism after nonmyeloablative syngeneic transplantation of bone marrow from young to old MiceFrontiers in Genetics2019
 General staining and segmentation procedures for high content imaging and analysisMethods Mol Biol2018
cancer, neuroscience, stem cells, organoidsGeneration of three-dimensional human neuronal cultures: application to modeling CNS viral infectionsStem Cell Research 2018
cancer, neuroscienceGranulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathologyActa Neuropathol2019
cancer, neuroscienceHigh content screening for drug discovery from traditional Chinese medicineChinese medicine2019
cancer, neuroscienceHigh levels of PIWI‐interacting RNAs are present in the small RNA landscape of prostate epithelium from vitamin D clinical trial specimensThe Prostate2019
cancer, virologyHigh-Content Screening, a Reliable System for Coxiella burnetii Isolation from Clinical SamplesJournal of Clinical Microbiol2020
cancer, neuroscienceHigh-Throughput Fluorescence Assays for Ion Channels and GPCRsAdv Exp Med Biol2020
virologyHigh-throughput isolation of giant viruses using high-content screeningCommunications Biology2019
 In Vitro High-Content Imaging-Based Phenotypic Analysis of Bronchial 3D Organotypic Air–Liquid Interface CulturesSLAS2020
cancer, neuroscience, stem cellsIn vitro screening platforms for identifying autophagy modulators in mammalian cellsAutophagy2019
neuroscienceInhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complexJ Cell Sci2018
cancer, neuroscienceIsoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scopariusJournal Asian Nat Prod Res2019
cancer, neuroscienceMARCKS regulates neuritogenesis and interacts with a CDC42 signaling networkScientific reports2018
neuroscience, stem cells, organoidsModeling Leigh syndrome using patient-specific induced pluripotent stem cellsOsaka City Med J2019
 Modular, defined assembly of antibody-based constructs using click chemistryKeystone Symposia2018
neuroscienceModulation of CRMP2 via (S)-Lacosamide shows therapeutic promise but is ultimately ineffective in a mouse model of CLN6-Batten diseaseHealth Psychol Behav Med2019
cancer, neuroscienceNew insights into mechanism of bisphenol analogue neurotoxicity: implications of inhibition of O-GlcNAcase activity in PC12 cellsArchives of Toxicology2019
cancer, neuroscienceNo evidence for cell‐to‐cell transmission of the unfolded protein response in cell cultureJournal of Neurochem2019
cancerNon-Toxic and Ultra-Small Biosilver Nanoclusters Trigger Apoptotic Cell Death in Fluconazole-Resistant Candida albicans via Ras SignalingBiomolecules2019
cancer, neuroscienceOPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretionJournal of Cell Science2020
neuroscience, stem cellsPartial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neuronsEuropean Journal of Neuroscience2019
cancer, neurosciencePhosphorylation of syntaxin 17 by TBK1 controls autophagy initiationDevelopmental Cell2019
cancer, neuroscience, stem cellsPopulation-based analysis of BAP1 germline variations in patients with uveal melanomaHuman Molecular Genetics2019
cancer, immunotherapy, stem cells, organoidsReplication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironmenteLife2019
cancer, neuroscience, stem cells, organoidsReview of high-content screening applications in toxicologyArchives of Toxicology2019
neuroscienceRole of the AP-5 adaptor protein complex in late endosome-to-Golgi retrievalPLoS Biol2018
cancer, neuroscience, stem cells, organoidsShedding light on microRNA function via microscopy-based screeningMethods2019
 Super-multiplexed fluorescence microscopy via photostability contrastBiomedical optics 2018
stem cellsthalidomide inhibits Human ipSc Mesendoderm Differentiation by Modulating cRBn-dependent Degradation of SALL4Scientific Reports2020
cancer, virologyThe ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon responsePLoS Pathog2019
 The WDR11 complex facilitates the tethering of AP-1-derived vesiclesNature Communication2018
cancerTools to measure autophagy using high content imaging and analysisMethods Mol Biol2018
cancer, neuroscienceUnconventional secretion factor GRASP55 is increased by pharmacological unfolded protein response inducers in neuronsScientific Reports2019
cancerVitamin D regulates prostate cell metabolism via genomic and non-genomic mitochondrial redox-dependent mechanismsThe Journal of Steroid Biochemistry and Molecular …2019
cancer, immunotherapyWedge-shaped microfluidic chip for circulating tumor cells isolation and its clinical significance in gastric cancerJournal Transl Med2018
cancer, 2D vs 3D, COVID, coronavirus, stem cellsHigh-content siRNA 3D co-cultures to identify myoepithelial cell-derived breast cancer suppressor proteinsScientific Data2021
cancer, stem cells, virology, coronavirus High-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activitiesCell Biol Toxicol2021
cancer, 2D vs 3DA Novel Imaging Approach for Single-Cell Real-Time Analysis of Oncolytic Virus Replication and Efficacy in Cancer CellsHum Gene Ther2021
cancerKEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung CancerCancers (Basel) 2021
COVID, coronavirus, virologyThe SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airwaysPLoS Pathogens2021
cancer, 2D vs 3DPreclinical Evaluation of Artesunate as an Antineoplastic Agent in Ovarian Cancer Treatment.Diagnostics (Basel)2021

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virologyA Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral EntryMolecular Biology of the Cell2018
neuroscienceA novel inhibitor of inducible NOS dimerization protects against cytokine‐induced rat beta cell dysfunctionBr J Pharmacol2018
virologyA novel piperazine-based drug lead for cryptosporidiosis from the medicines for malaria venture open-access malaria boxAntimicrob Agents Chemother2018
cancer, neuroscienceActivated heterotrimeric G protein αi subunits inhibit Rap-dependent cell adhesion and promote cell migrationJ Biol Chem2018
cancer, immunotherapyADME/toxicity prediction and antitumor activity of novel nitrogenous heterocyclic compounds designed by computer targeting of alkylglycerone phosphate …Oncol Lett2020
stem cellsAdvances in antiwolbachial drug discovery for treatment of parasitic filarial worm infectionsTrop Med Infect Dis2020
cancer, neuroscienceAnalysis of Gene Expression and Neuronal Phenotype in Neuroscreen-1 (NS-1) CellsInt J Biomed Investig2019
cancerBifunctional Au-templated RNA nanoparticles enable direct cell uptake detection and GRP75 knockdown in prostate cancerJ Mater Chem B2018
neuroscience, stem cells, virologyC9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transportSci Rep2019
immunotherapy, virologyConvergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus NeutralizationCell2018
immunotherapy, virologyDesign and evaluation of bi-and trispecific antibodies targeting multiple filovirus glycoproteinsJ Biol Chem2019
neuroscience, stem cellsDifferential effects of glucose deprivation on the survival of fetal versus adult neural stem cells‐derived oligodendrocyte precursor cellsGlia2018
 DMN-Tre Labeling for Detection and High-Content Screening of Compounds against Intracellular MycobacteriaACS Omega2018
cancerDownregulation of MicroRNA-4463 Attenuates High-Glucose-and Hypoxia-Induced Endothelial Cell Injury by Targeting PNUTSCell Physiol Biochem2019
cancer, organoidseIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinomaNature Communication2018
cancerEnhanced cancer theranostics with self-assembled, multilabeled siRNAsACS Omega2019
virologyFloxed-cassette allelic exchange mutagenesis enables markerless gene deletion in Chlamydia trachomatis and can reverse cassette-induced polar effectsJ Bacteriol2020
cancer, virologyFluorescently Labeled siRNAs and their Theranostic Applications in Cancer Gene TherapyACS Omega2018
neuroscience, stem cells, virologyFUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteinsHum Mol Genet2018
cancer, stem cellsGenome-Wide Association Study of Diabetogenic Adipose Morphology in the GENetics of Adipocyte Lipolysis (GENiAL) CohortCells2020
cancer, stem cellsGlucocorticoids delay RAF-induced senescence promoted by EGR1J Cell Sci2018
cancer, stem cellsGlutamine Links Obesity to Inflammation in Human White Adipose TissueCell Metabolism2020
cancer, neuroscience, stem cellsGRP78 modulates cell adhesion markers in prostate Cancer and multiple myeloma cell linesBMC Cancer2020
cancer, stem cellsGTPBP4 promotes gastric cancer progression via regulating P53 activityCell Physiol Biochem2019
cancer, virologyHemagglutinin Cleavability, Acid Stability, and Temperature Dependence Optimize Influenza B Virus for Replication in Human AirwaysJ Virol2019
cancerHerbicidins from Streptomyces sp. CB01388 Showing Anti-Cryptosporidium ActivityJ Nat Prod2019
cancer, neuroscienceHigh content screening for drug discovery from traditional Chinese medicineChin Med2018
 High-Content Screening for Cryptosporidium Drug DiscoveryMethods Mol Biol2019
cancerHighly Efficient Isolation of Circulating Tumor Cells Using a Simple Wedge-Shaped Microfluidic DeviceIEEE Trans Biomed Eng2019
immunotherapy, virologyHuman monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteinsPLoS Pathog2019
cancer, stem cellsHuman-specific function of IL-10 in adipose tissue linked to insulin resistanceJ Clin Endocrinol Metab2019
cancer, neuroscience, stem cellsIn vitro screening platforms for identifying autophagy modulators in mammalian cellsMethods Mol Biol2020
cancer, neuroscienceKnockdown siRNA targeting the mitochondrial sodium-calcium exchanger-1 inhibits the protective effects of two cannabinoids against acute paclitaxel toxicityJ Mol Neurosci2020
cancer, neuroscience, stem cellsMANF ablation causes prolonged activation of the UPR without neurodegeneration in the mouse midbrain dopamine systemeNeuro2019
cancerMicroRNA-27a/b-3p and PPARG regulate SCAMP3 through a feed-forward loop during adipogenesisSci Rep2020
cancer, neuroscienceMicroscopy-based automated live cell screening for small molecules that affect ciliationFront Genet2020
cancer, immunotherapy, organoidsModular, defined assembly of antibody-based constructs using click chemistryKeystone Symposia2019
cancer, neuroscienceN-substituted phenylbenzamides of the niclosamide chemotype attenuate obesity related changes in high fat diet fed micePLoS One2018
cancerPITPNA-AS1 abrogates the inhibition of miR-876-5p on WNT5A to facilitate hepatocellular carcinoma progressionCell Death Dis2018
cancer, neuroscience, stem cellsPossible Strategies to Optimize a Biomarker Discovery Approach to Correlate with Neurological Outcome in Patients with Spinal Cord Injury: A Pilot StudyJ Neurotrauma2018
cancer, neuroscience, stem cellsProlactin, Estradiol and Testosterone Differentially Impact Human Hippocampal Neurogenesis in an In Vitro ModelNeuroscience2018
cancer, neuroscienceProtective effect of 3-hydroxybutyrate against endoplasmic reticulum stress-associated vascular endothelial cell damage induced by low glucose exposurePLoS One2018
cancerPumpless platform for high-throughput dynamic multicellular culture and chemosensitivity evaluationLab Chip2019
stem cellsRecombinant extracellular matrix protein fragments support human embryonic stem cell chondrogenesisTissue Eng Part A2019
cancer, stem cells, organoidsShedding light on microRNA function via microscopy-based screeningMethods2018
cancer, immunotherapy, virologyStructural Basis of Broad Ebolavirus Neutralization by a Human Survivor AntibodyNat Struct Mol Biol2019
immunotherapy, stem cells, virologySystematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protectionCell2019
cancerTechniques to Enable 1536-Well Phenotypic ScreeningMethods Mol Biol2019
stem cellsThe microbiota regulates inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelinationPNAS2019
neuroscience, stem cellsThe role of nuclear receptors in the differentiation of oligodendrocyte precursor cells derived from fetal and adult neural stem cellsStem Cell Res2019
stem cells, virologyTHP-1 and Dictyostelium infection models for screening and characterization of anti-Mycobacterium abscessus hit compoundsAntimicrob Agents Chemother2019
cancer, virologyVesicular Stomatitis Virus-Based Vaccines Provide Cross-Protection against Andes and Sin Nombre Viruses.Viruses2019
cancer, stem cellsLoss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decayNature Cell Biology2021
cancer, stem cellsPharmacological Protein Kinase C Modulators Reveal a Pro-hypertrophic Role for Novel Protein Kinase C Isoforms in Human Induced Pluripotent Stem Cell-Derived CardiomyocytesFront Pharmacol2021
cancerTowards the development of safer by design TiO2-based photocatalytic paint: impacts and performancesEnvironmental Science Nano2021
immunology, COVID, coronavirus The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airwaysPLoS Pathogens2021
cancerStabilization of p18 by deubiquitylase CYLD is pivotal for cell cycle progression and viral replicationNPJ Precis Oncol2021
coronavirus, COVIDA single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidateNature 2020
 Inter-Laboratory Reproducibility and Interchangeability of 3R4F and 1R6F Reference Cigarettes in Mainstream Smoke Chemical Analysis and In Vitro Toxicity AssaysSciendo2021
cancer, stem cellsGATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPSC-derived cardiomyocytesArch Toxicol2020
 PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosisAnn Rheum Dis2020
cancer, neurological    Metabolite Profiling, Isolation of Cyclic Polyols, Antioxidant and Anti-inflammatory Activities of Aegle Marmelos: NMR and GC-MS Based Metabolomics StudyJournal of Herbs, Spices, and Medicinal Plants2020
cancer, RNAiHigh-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity Against Mycobacterium tuberculosisFrontiers in Microbiology2020
 Biotransformation of Food-Grade and Nanometric TiO2 in the Oral–Gastro–Intestinal Tract: Driving Forces and Effect on the Toxicity toward Intestinal Epithelial CellsNanomaterials (Basel)2020
COVID, coronavirus, virologyThe SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airwaysPLoS Pathogens2021
cancer stem cells, virologyLoss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decayPLoS Pathogens2021

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ApplicationTitleSourceYear
cancer, neuroscience, stem cells, organoids, virologyA fluorescent cell-based system for imaging Zika virus infection in real-timeViruses2018
cancerA genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrestNucleic Acids Res2019
stem cellsA head-to-head Caco-2 assay comparison of the mechanisms of action of the intestinal permeation enhancers: SNAC and sodium caprate (C10)European Journal of Pharm Biopharm2020
 A high content screening assay for identifying inhibitors against active and dormant state intracellular Mycobacterium tuberculosisJournal of Microbiological Methods2019
cancer, neuroscienceA Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small MoleculesScientific Reports2020
neuroscienceA Novel RNA editing sensor tool and a specific agonist determine neuronal protein expression of RNA-edited glycine receptors and identify a genomic …Frontiers in Molecular Neuro2018
cancer, stem cellsA novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylationOncotarget2019
cancer, neuroscience, stem cells, organoidsA SMN2 Splicing Modifier Rescues the Disease Phenotypes in an In Vitro Human Spinal Muscular Atrophy ModelStem Cells and Dev2019
cancer, neuroscienceA stress-enhanced model for discovery of disease-modifying gene: Ece1-suppresses the toxicity of α-synuclein A30PNeurobiology of Disease2018
cancer, stem cellsA β1-tubulin–based megakaryocyte maturation reporter system identifies novel drugs that promote platelet productionBlood Adv2018
cancer, neuroscienceActivation of Nrf2 signaling by salvianolic acid C attenuates NF‑κB mediated inflammatory response both in vivo and in vitroInt Immunopharmacol2018
cancer, virologyAdvanced identification of global bioactivity hotspots via screening of the metabolic fingerprint of entire ecosystemsScientific Reports2020
cancer, immunotherapy, stem cellsAdvanced Materials and Devices for the Regulation and Study of NK CellsInternational Journal of Molecular Sciences2019
cancerAMMECR1 Inhibits Apoptosis and Promotes Cell-cycle Progression and Proliferation of the A549 Human Lung Cancer Cell LineAnticancer Res2019
neuroscience, stem cellsAn analog derived from phenylpropanoids ameliorates Alzheimer's disease–like pathology and protects mitochondrial functionNeurobiology of Aging2019
cancer, stem cellsAn endothelial cell/mesenchymal stem cell coculture cord formation assay to model vascular biology in vitro

 

Methods Mol Biol

2018
 Analysis and quantification of oxidized low-density lipoprotein-induced lipid droplets in macrophages through high-content screening: Application for antiatherogenic …Assay and Drug Development Technologies2019
 Andrographolide protects chondrocytes from oxidative stress injury by activation of the Keap1–Nrf2–Are signaling pathwayJ Cell Physiol2019
cancerAnlotinib inhibits synovial sarcoma by targeting GINS1: a novel downstream target oncogene in progression of synovial sarcomaClinical and Translational Oncology2019
cancer, immunotherapy, neuroscienceAntibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomesScientific Reports2019
cancer, immunotherapyAnticancer Activity of Earthworm Powder (Lumbricus terrestris) Against MCF-7 and PC-3 Cancer Cell LinesJournal of Gastrointestinal Cancer2019
 Anti-inflammatory activity of dehydroandrographolide by TLR4/NF-κB signaling pathway inhibition in bile duct-ligated miceCell Physiol Biochem2018
cancer, neuroscienceAnti-inflammatory effects and mechanism of the total flavonoids from Artemisia scoparia Waldst. et kit. in vitro and in vivoBiomed Pharmacother2018
cancer, stem cellsArrayed functional genetic screenings in pluripotency reprogramming and differentiationStem Cell Research & Therapy2019
stem cellsAryl hydrocarbon receptor modulation by tuberculosis drugs impairs host defense and treatment outcomesCell Host & Microbe2020
cancerAssessment of novel tobacco heating product THP1. 0. Part 6: a comparative in vitro study using contemporary screening approachesRegul Toxicol Pharmacol2018
cancerATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failureGenetic Med2019
cancerAutomated Detection of Autophagy Response Using Single Cell-Based Microscopy AssaysAutophagy2019
cancer, neuroscience, stem cellsAutophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertensionJ Pathology2019
cancer, immunotherapy, stem cellsB591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cellsOncogene2019
cancerBAI1‑associated protein 2‑like 2 is a potential biomarker in lung cancerOncology Report2019
cancer, neuroscience, stem cellsBCL2 and BCL (X) L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2 …Oncotarget2018
neuroscienceBenzalkonium chloride-induced direct and indirect toxicity on corneal epithelial and trigeminal neuronal cells: proinflammatory and apoptotic responses in vitroToxicology letters2020
cancer, neuroscienceBioinspired Honokiol Analogs and Their Evaluation for Activity on the Norepinephrine TransporterMolecules2018
neuroscienceBlue light exposure in vitro causes toxicity to trigeminal neurons and glia through increased superoxide and hydrogen peroxide generationFree Radic Biol Med2019
 Breast Milk and Saliva Lactoferrin Levels and Postnatal Cytomegalovirus InfectionAm J Perinatol2020
cancer, stem cellsCardiac Toxicity From Ethanol Exposure in Human-Induced Pluripotent Stem Cell-Derived CardiomyocytesToxicol Sci2019
cancer, immunotherapyCasein Kinase 2 Interacting Protein-1 Suppresses Glioma Cell Proliferation via Regulating the AKT/GSK3/-Catenin PathwayBiomed Res Int2019
cancer, stem cellsCell-Based High Content Analysis of Cell Proliferation and ApoptosisHigh Content Screening2018
cancer, neuroscienceCell‐based high‐throughput screen for small molecule inhibitors of Bax translocationJ Cell Mol Med2019
cancerCellular fluorescein hyperfluorescence is dynamin-dependent and increased by Tetronic 1107 treatmentInt J Biochem Cell Biol2018
cancerChlamydia trachomatis fails to protect its growth niche against pro-apoptotic insultsCell Death Differ2019
cancerChloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusionAutophagy2018
cancer, immunotherapyCIZ1 knockdown suppresses the proliferation of bladder cancer cells by inducing apoptosisGene2019
cancerCombined PPARγ activation and XIAP inhibition as a potential therapeutic strategy for ovarian granulosa cell tumorsMol Cancer Therap2019
cancer, stem cells, virologyCompounds producing an effective combinatorial regimen for disruption of HIV‐1 latencyEMBO Mol Med2018
cancerConjugate Polyplexes with Anti-Invasive Properties and Improved siRNA Delivery In VivoBioconjugate Chemistry2018
cancer, neuroscience, stem cells, organoidsConstitutive Activity of a G Protein‐Coupled Receptor, DRD1, Contributes to Human Cerebral Organoid FormationSTEM CELLS2020
cancer, neuroscienceCoQ10 ameliorates mitochondrial dysfunction in diabetic nephropathy through mitophagyJ Endocrinol 
cancer, neuroscienceCyclin-dependent kinase 18 controls trafficking of aquaporin-2 and its abundance through ubiquitin ligase STUB1, which functions as an AKAPCells2020
cancerCyclodextrin-and dendrimer-conjugated graphene oxide as a nanocarrier for the delivery of selected chemotherapeutic and photosensitizing agentsMater Sci Eng C Mater Biol Appl2018
cancer, neuroscience, stem cellsCytotoxic Mechanism for Silver Nanoparticles Based High-Content Cellomics and Transcriptome SequencingJ Biomed Nanotechnol2019
cancerDelivery of miR-146a to Ly6Chigh monocytes inhibits pathogenic bone erosion in inflammatory arthritisTheranostics2018
cancer, neuroscience, stem cellsDetection of Rare Objects by Flow Cytometry: Imaging, Cell Sorting, and Deep Learning ApproachesIntl J Mol Science2020
cancerDevelopment and application of high-content biological screening for modulators of NET productionFrontiers in Immunol2018
 Development and optimization of a miniaturized western blot-based screening platform to identify regulators of post-translational modificationsHigh-throughput2019
neuroscienceDevelopment of a cell-based assay to assess binding of the proNGF prodomain to sortilinCell Mol Neuro 2018
cancer, immunotherapy, stem cells, virologyDevelopment of a novel screening platform for the identification of small molecule inhibitors of human adenovirusVirology2019
cancer, neuroscience, stem cellsDevelopment of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of DrugsNeuroscience Bull2019
cancerDiazinon exposure activated transcriptional factors CCAAT-enhancer-binding proteins α (C/EBPα) and peroxisome proliferator-activated receptor γ (PPARγ) and …Pesticide Biochemistry and Physiology2018
 Differentiated mitochondrial function in mouse 3T3 fibroblasts and human epithelial or endothelial cells in response to chemical exposureBasic Clin Pharmacol Toxicol2019
cancerDifferentiation of Aneugens and Clastogens in the In Vitro Micronucleus Test by Kinetochore Scoring Using Automated Image AnalysisEnviron Mol Mutagen2019
neuroscienceDirect, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit α 2 δ-1 with thrombospondin-4Scientific Reports2019
cancerDiscovery of the first potent, selective, and orally bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) inhibitor displaying pronounced immunomodulatory effects …J Med Chem2018
cancerDiscovery of the Polyamine Conjugate with Benzo[cd]indol-2(1H)-one as a Lysosome-Targeted Antimetastatic AgentJ Med Chem2018
cancer, neuroscienceDownregulation of CPA4 inhibits non small–cell lung cancer growth by suppressing the AKT/c‐MYC pathwayMol Carcinogen2019
cancerDownregulation of RNA binding motif protein 17 expression inhibits proliferation of hypopharyngeal carcinoma FaDu cellsOncology2018
cancer, neuroscienceDownregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent …Cancer Biol Med2020
cancer, immunotherapy, neuroscienceDrug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeuticsMed Res Rev2020
virologyDual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesisScientific reports2019
cancer, neuroscience, stem cells, organoidsDYRK1A Is a Regulator of S-Phase Entry in Hepatic Progenitor CellsStem Cells Dev2018
 Elevated transforming growth factor β signaling activation in β‐actin‐knockout mouse embryonic fibroblasts enhances myofibroblast featuresJournal of cellular physiology2018
cancerElongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome StabilityMolecular cell2019
virologyEndophilin-A2-mediated endocytic pathway is critical for enterovirus 71 entry into caco-2 cellsEmerging microbes & …2019
cancerEndoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytesFree Radic Biol Med2018
 Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatmentScientific reports2018
cancerExploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathwayJ Bone Oncol2019
cancer, immunotherapyExtracellular DNA promotes colorectal tumor cell survival after cytotoxic chemotherapyJ Surg Res2018
cancer, stem cellsExtracellular vesicles induce minimal hepatotoxicity and immunogenicityNanoscale2019
cancerFunctional characterization of glucocorticoid receptor variants is required to avoid misinterpretation of NGS dataJ Endocr Soc2019
cancerFunctional Comparison of XPF Missense Mutations Associated to Multiple DNA Repair DisordersGenes2019
virologyFunctional insights into the adjacent stem-loop in honey bee dicistroviruses that promotes internal ribosome entry site-mediated translation and viral infectionJournal of virology2018
cancerFunctional regulation of human trophoblast cells by CSE1LJ Matern Fetal Neonatal Med2019
 Fuzhenghuayu Decoction ameliorates hepatic fibrosis by attenuating experimental sinusoidal capillarization and liver angiogenesisScientific Reports2019
neuroscience, stem cellsFZD4 marks lateral plate mesoderm and signals with NORRIN to increase cardiomyocyte induction from pluripotent stem cell-derived cardiac progenitorsStem Cell Reports2018
cancer, neuroscience, stem cellsGenes and pathways regulated by androgens in human neural cells, potential candidates for the male excess in autism spectrum disorderBiol Psychiatry2018
cancer, stem cellsGenetic and chemical screenings identify HDAC3 as a key regulator in hepatic differentiation of human pluripotent stem cellsStem Cell Reports2018
cancerGlutathione accelerates osteoclast differentiation and inflammatory bone destructionFree Radical Res2019
cancer, stem cellsGlycylglycine plays critical roles in the proliferation of spermatogonial stem cellsMolecular Med Rep2019
neuroscienceGPR146 Deficiency Protects against Hypercholesterolemia and AtherosclerosisCell2019
cancerHigh content imaging assays for IL-6-induced STAT3 pathway activation in head and neck cancer cell linesMethod Mol Bio2018
cancer, virologyHigh content positional biosensor assay to screen for compounds that prevent or disrupt androgen receptor and transcription intermediary factor 2 protein-protein …Method Mol Bio2018
cancer, neuroscienceHigh content screening in NHBE cells shows significantly reduced biological activity of flavoured e-liquids, when compared to cigarette smoke condensateToxicology in Vitro2019
cancer, stem cellsHigh content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastomaPloS One2018
cancer, neuroscienceHigh glucose triggers nucleotide imbalance through O-GlcNAcylation of key enzymes and induces KRAS mutation in pancreatic cellsCell Metabolism2019
cancer, neuroscienceHigh-Content Imaging of Immunofluorescently Labeled TRPV1-Positive Sensory NeuronsMethod Mol Bio2019
stem cells, organoidsHigh-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targetsJournal of Molecular and Cell Cardiol2019
neuroscience, stem cellsHigh‐throughput identification of factors promoting neuronal differentiation of human neural progenitor cells in microscale 3D cell cultureBiotechnology and Bioeng2019
cancer, neuroscience, stem cellsHost-targeted niclosamide inhibits C. difficile virulence and prevents disease in mice without disrupting the gut microbiotaNat Commun2018
cancer, immunotherapy, neuroscienceHuman corticotrophin releasing factor inhibits cell proliferation and promotes apoptosis through upregulation of tumor protein p53 in human gliomaOncology Letters2018
stem cellsHuman pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesisNat Commun2019
cancer, neuroscience, stem cellsHuman-derived neurons and neural progenitor cells in high content imaging applicationsMethod Mol Bio2018
 Identification and analyses of inhibitors targeting apolipoprotein (a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain functionJournal of Biological Chemistry2020
cancerIdentification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME ScreenAutophagy2019
neuroscience, stem cellsIdentification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neuronsEur J Med Chem2019
cancer, neuroscience, virologyIdentification of Hsp90 inhibitors with anti-Plasmodium activityAntimicrobial Agents Chemotherapy2018
stem cellsIn vivo expansion of functional human hematopoietic stem progenitor cells by butyzamideInternational Journal of Hematology2020
cancer, stem cellsIn-depth proteome analysis highlights HepaRG cells as a versatile cell system surrogate for primary human hepatocytesCells2019
cancer, neuroscienceInduction of migration of periodontal ligament cells by selective regulation of integrin subunitsJournal of Cellular Mol Med2019
cancer, neuroscienceInflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell deathNeurobiology of Disease2018
cancer, stem cellsInhibition of human prostate cancer (PC-3) cells and targeting of PC-3-derived prostate cancer stem cells with koenimbin, a natural dietary compound from …Drug Design Devel Ther2018
cancer, neuroscienceInhibition of myostatin signal pathway may be involved in low-intensity pulsed ultrasound promoting bone healingJournal of Medical Ultrason2019
cancerInhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo-and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation StatusCancers2019
neuroscienceInhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complexJ Cell Sci2018
cancer, neuroscienceInhibition of the MID1 protein complex: a novel approach targeting APP protein synthesisCell Death Discovery2018
virologyIntegrative analysis of Zika virus genome RNA structure reveals critical determinants of viral infectivityCell Host & Microbe2018
 Interaction of mycobacteria with Plasmin (ogen) affects phagocytosis and granuloma developmentTuberculosis2019
neuroscience, virologyInterferon-induced transmembrane protein 1 restricts replication of viruses that enter cells via the plasma membraneJournal of Virology2019
cancerKIAA0101 inhibition suppresses cell proliferation and cell cycle progression by promoting the interaction between p53 and Sp1 in breast cancerBiochemical and Biophysical Research 2018
cancer, stem cellsKLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the boneOncogene2019
cancerKnockdown expression of MECR, a novel gene of mitochondrial FAS II inhibits growth and colony-formation, promotes apoptosis of hepatocellular carcinoma cellsBioscience Trends2019
cancerKnockdown of CCNO decreases the tumorigenicity of gastric cancer by inducing apoptosisOncoTargets and Ther2018
cancer, neuroscienceKnockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expressionBioscience Reports2020
cancerKnockdown of PSMC3IP suppresses the proliferation and xenografted tumorigenesis of hepatocellular carcinoma cellJournal of Cellular Biochem2019
cancer, stem cellsKnockdown of ubiquitin associated protein 2-like (UBAP2L) inhibits growth and metastasis of hepatocellular carcinomaMedical Science Monitor 2018
cancer, immunotherapy, neuroscienceKushenol E inhibits autophagy and impairs lysosomal positioning via VCP/p97 inhibitionBiochemical Pharmacol2020
cancer, neuroscience, stem cellsLack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clustersScientific Reports2018
cancer, virologyLentivirus mediated γ-interferon-inducible lysosomal thiol reductase (GILT) knockdown suppresses human glioma U373MG cell proliferationBiochem Biophys Res Commun2019
cancerLIMD 1 phosphorylation in mitosis is required for mitotic progression and its tumor‐suppressing activityFEBS2019
cancer, neuroscience, virologyLINE-1 protein localization and functional dynamics during the cell cycleElife2018
cancer, neuroscienceLipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic …European Journal of Med Chem2020
 Live-cell measurements of kinase activity in single cells using translocation reportersNature Protocols2018
stem cellsLong-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantationNature2019
virologyMagnitude and diversity of immune response to vaccinia virus is dependent on route of administrationVirology2020
cancerMAT2B expression correlates with poor prognosis in triple-negative breast cancerCancer Management and Research2019
cancer, stem cells, organoidsMDH1 and MPP7 regulate autophagy in pancreatic ductal adenocarcinomaCancer Research2019
cancerMicroRNA-27a controls the intracellular survival of Mycobacterium tuberculosis by regulating calcium-associated autophagyNature Comms2018
cancer, stem cellsMicroscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell linesArchives of Tox2018
cancer, stem cellsmiR-122 release in exosomes precedes overt tolvaptan-induced necrosis in a primary human hepatocyte micropatterned coculture modelToxicological Sci2018
cancer, neurosciencemiR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3–Binding Domain to Regulate Wnt1Molecular Cancer Res2019
 miR-182-3p/Myadm contribute to pulmonary artery hypertension vascular remodeling via a KLF4/p21-dependent mechanismTheranostics2020
cancer, stem cellsmiR-211 sponges lncRNA MALAT1 to suppress tumor growth and progression through inhibiting PHF19 in ovarian carcinomaThe FASEB Journal2018
cancer, neuroscienceMitochondria are transported along microtubules in membrane nanotubes to rescue distressed cardiomyocytes from apoptosisCell Death & Disease2018
cancerMonosomy 18p is a risk factor for facioscapulohumeral dystrophyJournal of Medical Genetics2018
cancer, neuroscienceMTP18 is a Novel Regulator of Mitochondrial Fission in CNS Neuron Development, Axonal Growth, and Injury ResponsesScientific Reports2019
cancerMuscarinic acetylcholine type 1 receptor activity constrains neurite outgrowth by inhibiting microtubule polymerization and mitochondrial trafficking in adult …Frontiers in Neuroscience2018
cancer, neuroscienceMuscarinic receptor antagonists activate ERK-CREB signaling to augment neurite outgrowth of adult sensory neuronsNeuropharmacology2018
cancer, stem cellsNaCl nanoparticles as a cancer therapeuticAdvanced Materials2019
cancer, neuroscienceN-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expressionScientific Reports2018
 Nanoscale coupling of endocytic pit growth and stabilityScience Adv2019
cancer, neuroscienceNHE5 regulates growth factor signaling, integrin trafficking, and degradation in glioma cellsClinical & Experimental Metastasis2019
cancer, neuroscience, stem cellsNovel 3D liquid cell culture method for anchorage-independent cell growth, cell imaging and automated drug screeningScientific Reports2018
cancer, neuroscienceNuclear myosin 1 activates p21 gene transcription in response to DNA damage through a chromatin-based mechanismCommunications Biology2020
cancer, virologyOptimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptideeLife2019
cancerPanduratin A induces protective autophagy in melanoma via the AMPK and mTOR pathwayPhytomedicine2018
cancer, neuroscience, stem cellsPer-and polyfluoroalkyl substances impact human spermatogenesis in a stem-cell-derived modelSystems Biology in Reprod Med2018
cancer, neuroscience, stem cellsPhenotypic and functional characteristics of human Schwann cells as revealed by cell-based assays and RNA-seqMolecular Neurobiology2018
cancerPlagioneurin B, a potent isolated compound induces apoptotic signalling pathways and cell cycle arrest in ovarian cancer cellsApoptosis2018
cancer, neuroscience, stem cellsPP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemiaScience Translational Med2018
cancer, neurosciencePreclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancerOncotarget2018
 Pro-inflammatory cytokines enhance dilatation of bile canaliculi caused by cholestatic antibioticsToxicology in Vitro2019
cancerProtein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophyJournal of Biological Chemistry2018
cancer, neuroscience, stem cellsProteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout miceHuman Molecular Genetics2018
 Ptr/CTL0175 is required for the efficient recovery of Chlamydia trachomatis from stress induced by gamma-interferonFrontiers in Microbiology2019
cancerPu-erh tea relaxes the thoracic aorta of rats by reducing intracellular calciumFront Pharmacol2019
 Quercetin protect cigarette smoke extracts induced inflammation and apoptosis in RPE cellsArtif Cells Nanomed Biotechnol2019
cancerRBM17 controls apoptosis and proliferation to promote Glioma progressionBiochem Biophys Res Commun2018
cancer, neuroscienceReal-time monitoring of DNA G-quadruplexes in living cells with a small-molecule fluorescent probeNucleic Acids Research2018
cancer, neuroscience, stem cells, organoidsRecent Advances in Microfluidic Techniques for Systems BiologyAnalytical Chemistry2018
cancerRegulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanomaPNAS2019
cancer, neuroscience, stem cellsRepression of somatic genes by selective recruitment of HDAC3 by BLIMP1 is essential for mouse primordial germ cell fate determinationCell Reports2018
cancer, neuroscienceReversine inhibits colon carcinoma cell migration by targeting JNK1Scientific Reports2018
cancerRole of miR‑449b‑3p in endometriosis via effects on endometrial stromal cell proliferation and angiogenesisMolecular Medicine Reports2018
cancer, neuroscienceRPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availabilityNature Cell Biology2019
cancer, neuroscienceSevere PATCHED1 deficiency in cancer-prone Gorlin patient cells results in intrinsic radiosensitivityInt J Radiat Oncol Biol Phys2018
cancer, neuroscienceSoluble laminin polymers enhance axon growth of primary neurons in vitroJournal of Biomedical Chemistry2018
neuroscienceSpecific Knockdown of α-Synuclein by Peptide-Directed Proteasome Degradation Rescued Its Associated NeurotoxicityCell Chemical2020
cancerSpontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV IntegrinsNephron2019
cancerStable Redox-Cycling Nitroxide Tempol Has Antifungal and Immune-Modulatory PropertiesFrontiers in Microbiology2019
cancerStaphylococcus aureus induces DNA damage in host cellScientific Reports2019
cancer, neuroscienceStructural analysis and cellular visualization of APP RNA G-quadruplexChemical Science2019
stem cellsSuppression of adipocyte differentiation by low‐intensity pulsed ultrasound via inhibition of insulin signaling and promotion of CCN family protein 2Journal of Cellular Biochem2020
cancerSuppression of CCT3 inhibits malignant proliferation of human papillary thyroid carcinoma cellOncology Letters2018
cancerSynthesis and evaluation of 1, 3, 4-oxadiazole derivatives for development as broad-spectrum antibioticsBioorganic & Medicinal Chem2019
cancer, neuroscienceSynthetic probe development for measuring single or few-cell activity and effluxMethods in Enzymology2019
 Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cellsToxicology Reports2020
neuroscience, stem cells, organoidsTesting for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopmentToxicology and Applied Pharmcol2018
cancerTFIIA transcriptional activity is controlled by a 'cleave-and-run'Exportin-1/Taspase 1-switchJournal of Molecular Cell Bio2018
cancerTGFβ promotes genomic instability after loss of RUNX3Cancer Research2018
stem cellsthalidomide inhibits Human ipSc Mesendoderm Differentiation by Modulating cRBn-dependent Degradation of SALL4Scientific Reports2020
cancer, neuroscience, stem cellsThe AMPK/p27Kip1 axis regulates autophagy/apoptosis decisions in aged skeletal muscle stem cellsStem Cell Reports2018
cancerThe antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418PloS One2019
cancer, neuroscienceThe biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco productToxicology in Vitro2018
cancer, stem cellsThe Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor SuppressionCell Reports2018
cancer, neuroscience, stem cellsThe dynamics of TGF-β signaling are dictated by receptor trafficking via the ESCRT machineryCell Reports2018
cancer, neuroscienceThe effect of Jun dimerization on neurite outgrowth and motif bindingMolecular and Cellular Neuroscience2018
cancerThe glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinomaOncogene2018
cancerThe lead optimization of the polyamine conjugate of flavonoid with a naphthalene motif: Synthesis and biological evaluationEuropean Journal of Med Chem2018
cancer, neuroscienceThe relative composition of actin isoforms regulates cell surface biophysical features and cellular behaviorsBiochimica et Biophysica 2018
 The secreted protein kinase CstK from Coxiella burnetii influences vacuole development and interacts with the GTPase-activating host protein TBC1D5Journal of Biological Chemistry2020
cancerThe tetrahydroxanthone-dimer phomoxanthone A is a strong inducer of apoptosis in cisplatin-resistant solid cancer cellsBioorganic & Medicinal  Chemistry2019
neuroscience, stem cellsTilianin mediates neuroprotection against ischemic injury by attenuating CaMKII-dependent mitochondrion-mediated apoptosis and MAPK/NF-κB signalingLife Sciences2019
cancer, neuroscience, stem cellsTools to measure cell health and cytotoxicity using high content imaging and analysisMethods Mol Biol2018
neuroscience, stem cellsTranscriptomically Guided Mesendoderm Induction of Human Pluripotent Stem Cells Using a Systematically Defined Culture SchemeStem Cell Reports2019
virologyTransmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cellsScientific Reports2018
neuroscienceTriclosan Affects Ca2+ Regulatory Module and Musculature Development in Skeletal Myocyte during Early Life Stages of Zebrafish (Danio rerio)Environmental Science & Technology2019
cancerUBE2S promotes the proliferation and survival of human lung adenocarcinoma cellsBMB reports2018
cancer, neuroscienceUBQLN4 represses homologous recombination and is overexpressed in aggressive tumorsCell2019
neuroscienceUnconventional secretion factor GRASP55 is increased by pharmacological unfolded protein response inducers in neuronsScientific Reports2019
cancer, neuroscienceVitegnoside Mitigates Neuronal Injury, Mitochondrial Apoptosis, and Inflammation in an Alzheimer's Disease Cell Model via the p38 MAPK/JNK PathwayJournal of Alzheimer's Dis2019
cancerWee1 inhibitor AZD1775 effectively inhibits the malignant phenotypes of esophageal squamous cell carcinoma in vitro and in vivoFrontiers in Pharmacol2019
cancerYAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodelingJournal of Transl Med2020
cancer, stem cellsYES1 is a targetable oncogene in cancers harboring YES1 gene amplificationCancer Research2019
cancer, neuroscience, stem cellsβ-Actin–dependent global chromatin organization and gene expression programs control cellular identityThe FASEB Journal2018