Texas Red® (and Texas Red®-X) Dye

Invitrogen Texas Red dye is a bright red-fluorescent dye with excitation ideally suited to the 561 or 594 nm laser lines. It is commonly conjugated to antibodies and proteins for cellular imaging applications.

Texas Red sulfonyl chloride is susceptible to hydrolysis and its low solubility in water may complicate its conjugation to some biomolecules. To overcome this difficulty, we offer Invitrogen Texas Red-X succinimidyl ester, which contains an additional seven-atom aminohexanoyl spacer ("X") between the fluorophore and its reactive group. Some conjugates are offered in the Texas Red-X formulation.

For brighter conjugates and greater photostability, we offer a Texas Red dye alternative—Invitrogen Alexa Fluor 594—as a reactive dye or conjugated to a variety of antibodies, peptides, proteins, tracers or amplification substrates optimized for cellular labeling and detection.


Texas Red (and Texas Red-X) dye

Initial brightness

Texas Red dye is a traditional red-fluorescent dye that has been used extensively to label protein conjugates such as phalloidins for cytoskeleton counterstaining or antibody conjugates for immunofluorescence.  

Photostability in buffer


Photostability in antifade


  561/594 Texas Red 596 615  
Laser line

Common filter set

Excitation max

Emission max


Texas Red (and Texas Red-X) dye products

We offer a broad range of Texas Red and Texas Red-X dye products including secondary antibodies, labeling kits, bioconjugates, and more:


UV-irradiated muntjac skin fibroblasts showing mitochondrial damage.

Fixed, permeabilized cells were stained with Invitrogen Texas Red-X phalloidin to visualize F-actin in the cytoskeleton. Endogenous biotin in the mitochondria was detected with Invitrogen Alexa Fluor 488 streptavidin. Nuclei were counterstained with DAPI (Cat. No. D1306, D3571, D21490).

Texas Red reactive dyes

Select dye-labeling chemistries for conjugation with the following reactive groups: 

Texas Red dye protein/antibody labeling kits

Select an optimized labeling kit for your target antibody or protein:

Target protein Kit Cat. No.
Conventional antibody/protein labeling
1 mg antibody/protein Texas Red Antibody/Protein Labeling Kit T10244

High-performance alternatives to Texas Red dye

Reactive dyes and conjugates

The Alexa Fluor 594 dye—with spectral properties and quantum yield nearly identical to those of Texas Red dye—has excellent solubility and produces brighter, more photostable conjugates. These conjugates are ideal for imaging and other applications requiring increased sensitivity and environmentally insensitive fluorescence detection.

Learn more about Alexa Fluor 594 dye

Phalloidin conjugates

Fluorescent conjugates of phalloidin using the Invitrogen Alexa Fluor dyes are now the preferred F-actin stains for most applications across the full spectral range. The Invitrogen Alexa Fluor phalloidin conjugates provide researchers with fluorescent probes that are designed to be superior in brightness and photostability to all other spectrally similar conjugates tested.

Learn more about Alexa Fluor phalloidin conjugates

Dextran conjugates

Fluorescent conjugates of dextran using the Alexa Fluor dyes are used for direct imaging of cell structures like neuronal projections or cell processes like endocytosis. The Invitrogen Alexa Fluor dextran conjugates provide researchers with fluorescent probes that are designed to be superior in brightness and photostability to all other spectrally similar conjugates tested.

Learn more about Alexa Fluor dextran conjugates



Molecular Probes Handbook

Cell stain tool

The significantly revised 11th Edition is the most complete fluorescence labeling and detection reference available. The Molecular Probes Handbook can help you achieve the best experimental results for your fluorescence labeling and detection experiments. View the handbook online or order your own copy.

Go to the Handbook online
Order your copy of the Handbook

Antifade reagents

Cell stain tool

Antifade reagents suppress photobleaching and preserve the signals of your fluorescently labeled target molecules. They offer excellent compatibility with a multitude of dyes across the spectrum, making them especially valuable tools for multicolor applications. For added convenience, some formulations include the nuclear counterstain DAPI, eliminating the need for a separate counterstaining step.

See the performance of this dye in SlowFade Antifade reagents
See the performance of this dye in ProLong Antifade reagents

Cell stain tool

Cell stain tool

Stain your own cell by using our simulation tool to develop reproducible results with many of our signature fluorescent dyes. Develop your multiplexing strategy for antibody probes, reactive dyes, and counterstains to create your perfectly labeled fluorescent cell.

Go to the cell stain tool

Fluorescence SpectraViewer


Plot and compare spectra and check the spectral compatibility for common fluorophores including all of the fluorescent probes from Thermo Fisher Scientific. The Fluorescence SpectraViewer tool is formatted for both microscope imaging and flow cytometry applications.

Go to the Fluorescence SpectraViewer

Not for resale. Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company.