Gene silencing or knockdown can be done easily now in most cell types, but there are a few things you need to consider before starting:

  • First, you’ll need to design the siRNA (small interferring RNA) against your gene
  • Second, you’ll need to deliver it to the cells effectively with a siRNA transfection procedure

Which siRNA transfection product is right for you?

  Order now Order now Order now Order now
  High efficiency versatile reagent for a wide range of common cell types Most efficient versatile reagent for the widest range of cell types including difficult-to-transfect cells Most efficient reagent for siRNA/miRNA delivery. Efficient gene knock-down. High-efficiency electroporation for all cell lines. Best for Primary & Stem Cells
  Lipofectamine™ 2000
Learn more
Lipofectamine™ 3000
Learn more
Lipofectamine™ RNAiMAX
Learn more
Neon™ Transfection System
Learn more
Top Selling Format Catalog #11668-019 - 1.5 mL Catalog #L3000-015 - 1.5 mL Catalog #13778-075 - 0.75 mL Catalog #MPK5000S
Sample Type
  • DNA
  • RNA
  • Co-transfection
  • DNA
  • RNA
  • Co-transfection
  • RNA
  • DNA
  • RNA
  • Co-transfection
  • Protein
Transfection Efficiency High Superior Superior Maximal
Cell Viability High Superior Superior Good
Protocol Download Protocol Download Protocol Download Protocol Download Protocol

Which siRNA transfection product is right for you?

High efficiency versatile reagent for a wide range of common cell types Most efficient versatile reagent for the widest range of cell types including difficult-to-transfect cells Most efficient reagent for siRNA/miRNA delivery. Efficient gene knock-down. High-efficiency electroporation for all cell lines. Best for Primary & Stem Cells
Order now Order now Order now Order now
  Lipofectamine™ 2000
Learn more
Lipofectamine™ 3000
Learn more
Lipofectamine™ RNAiMAX
Learn more
Neon™ Transfection System
Learn more
Top Selling Format Catalog #11668-019 - 1.5 mL Catalog #L3000-015 - 1.5 mL Catalog #13778-075 - 0.75 mL Catalog #MPK5000S
Sample Type
  • DNA
  • RNA
  • Co-transfection
  • DNA
  • RNA
  • Co-transfection
  • RNA
  • DNA
  • RNA
  • Co-transfection
  • Protein
Transfection Efficiency High Superior Superior Maximal
Cell Viability High Superior Superior Good
Protocol Download Protocol Download Protocol Download Protocol Download Protocol
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