KingFisher Sample Purification Systems

Simple, powerful, automated sample preparation for DNA, RNA, proteins, and cells.


KingFisher Sample Purification Systems offer versatile laboratory benchtop automation for consistent extraction and purification of DNA, RNA, proteins, and cells. They serve a variety of applications, from SARS-CoV-2 and other viral/pathogen nucleic acid testing, to genomic DNA (gDNA) for genetic testing, to FFPE and cell-free DNA (cfDNA) for tissue and liquid biopsies, to protein isolation and peptide mapping, to T cell and exosome research.


KingFisher system workflows remove manual steps and reduce overall processing time compared with other automation systems. In addition, the systems offer optimized, easy-to-follow protocols for nearly every sample type.


KingFisher systems help reduce user processing errors while increasing the reproducibility of your results. Our data show that samples processed with KingFisher systems maintain consistent results across runs and different users, which is crucial for more sensitive downstream applications such as qPCR, NGS, digital PCR, and mass spectrometry.


Empower your laboratory beyond SARS‑CoV‑2 research and testing

Multiple applications are available for your versatile KingFisher sample preparation instrument.

Trade-in your KingFisher Flex instrument for the new KingFisher Apex instrument

Take advantage of our Thermo Fisher Scientific KingFisher trade-in/trade-up program and experience the most advanced automated sample prep technology.

KingFisher Apex instrument

High-throughput SARS-CoV-2 testing

KingFisher systems are on the front line helping labs accelerate RNA extraction throughput to handle the huge demand for fast and accurate SARS-CoV-2 test results.*

DNA and RNA applications

Kits and reagents optimized for KingFisher instruments can isolate many kinds of nucleic acids, such as gDNA, cfDNA, viral RNA, and miRNA, from a wide range of samples.

Protein and peptide applications

KingFisher systems can automate the isolation of individual proteins using immunoprecipitation, and automate protein digestion for peptide mapping and quantitation.

The consistency of Dynabeads reagents

Optimization of KingFisher instruments for Dynabeads magnetic bead reagents is central to consistent binding and reliable, reproducible results.

* For Research Use Only. Not for use in diagnostic procedures.