KingFisher Apex System

The Thermo Scientific KingFisher Apex represents the pinnacle of automated purification for DNA, RNA, proteins, and cells. Building on decades of KingFisher product value and excellence, we’ve combined exceptional instrument capabilities with complete touchscreen-based control to deliver excellent flexibility and performance. The KingFisher Apex makes sample prep easy.

Explore KingFisher Apex with a self-guided tour

Virtually navigate the KingFisher Apex instrument and get a closer look at the features, supporting kits and reagents, and more!



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In addition to the common features of all KingFisher Purification Systems, the Apex offers:

High-throughput purification
1–96 samples per run


Choose from two plate formats
Wide 20 μL–5 mL volume range


Download protocols from our library
Or easily customize protocols using Thermo Scientific BindIx Software

Easy to install and run with simple workflow
Follow on-screen instructions (including color guided plate loading) and start first run in <10 minutes

Security & maintenance features
User login and access levels for added security. Pop-up reminders for yearly maintenance.

Ultraviolet lamp
Decontamination is standard

Elute directly to PCR plates
Store your samples for later use with PCR compatible storage tubes

Touchscreen control

A modern touchscreen display and an intuitive interface puts you in control of instrument operation. Follow the guided visuals for easy plate loading, protocol changes, and instrument setup.


It’s easy to edit or write protocols directly on the instrument, and you can customize protocols at every step—bind, wash, elute. You also have the option to manage protocols on your PC with BindIx software. Instrument-defined limits help reduce potential errors in any protocol modifications.

KingFisher Apex touchscreen interactive demo
Click buttons to see preview

Dual magnets, tip combs, and plates


Dual magnets, multiple formats

When you install two magnets and heating blocks, KingFisher Apex intelligently selects the correct magnetic head based on your protocol. Work from large to small volume ranges by choosing from 24-well, 96-well, or PCR formats with corresponding magnetic heads and plates.

Interested in diagnostic nucleic acid extraction?

Demo videos

Protocols and software

Thermo Scientific BindIx software is included with KingFisher Apex instruments. The software makes it easy to create, download, run, modify, and store protocols directly on the instrument or on your PC.


Protocols are available for nucleic acid and protein purification procedures with reagent kits. The software allows you to define and edit steps, parameters, plates, and reagents for every part of your protocol—bind, wash, and elute. You can even generate status reports including a run log, plate layout, and step parameters.


For more information about BindIx, see the Features tab.

Attention KingFisher Flex users: KingFisher Flex scripts and protocols can be readily opened and converted to KingFisher Apex scripts.

To download BindIx software, choose one of the methods in the table. 


Three ways to download BindIx software



Web link

Double-click the downloaded package to start the installation process

Microsoft Store

Click Get, then Install

USB drive from manufacturer

Double-click the .msix bundle file, then click Install

 System requirements: Windows 10 version 1809 (17763.0) or higher


The KingFisher Apex can gently and efficiently isolate and purify nucleic acids, proteins, and cells from a range of sample types for a wide variety of downstream applications. For a selection of application kits, reagents, and protocols that run on the KingFisher Apex, see the Kits, Reagents, and Protocols tab.

Plates, plastics, and setup

For information about plastics and plate setup products designed to work with the KingFisher Apex, see the Accessories tab.




Instrument size


Throughput level

Medium to high

Processing volume by plate format

96-well plate

  • Deep-well: 50–1,000 µL
  • KingFisher standard: 15–200 µL
  • PCR: 10–80 µL

24-well plate

  • Deep-well: 30–5,000 µL

Storage tubes

  • 96 tubes: 30–200 µL
  • 24 tubes: 200–1,000 µl

Samples per run

24 or 96

Software included


Customizable protocols

Yes, created with instrument user interface or BindIx PC software*

Heating/cooling ranges

Heating up to 100ºC
Cooling down to 4ºC

Ultraviolet lamps

2 UV lamps, max run time 23 h 59 min

Dimensions (H x W x D)

45 x 78 x 59 cm (18 x 31 x 23 in)


56 kg (123 lb)

Plate formats

96 deep-well plate
96-well KingFisher standard plate
96-well PCR plate (skirted and semiskirted)
24 deep-well plate
96 storage tubes
24 storage tubes

Instrument memory

~30 GB

Display interface

Graphical user interface with touch screen


100–240 VAC 50/60 Hz, 280 VA

Barcode reader

On instrument; 1D barcodes

Magnetic head options

4 options, customer interchangeable

Data connectivity

USB device for PC
USB Wi-Fi or LAN adapter for network
RS-232 for automation
Cloud enabled

* Requires Windows 10 version 1809 (17763.0) or higher.

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