Nucleic acid electrophoresis uses a gel matrix to separate DNA and RNA fragments based on size and molecular weight. In blotting, DNA and RNA fragments, separated by electrophoresis, are transferred to a membrane matrix. Probes are then used to detect the presence of target sequences on the membrane matrix. Specific DNA and RNA sequences in a sample are detected by Southern and Northern blots, respectively. Nucleic acid electrophoresis and blotting are chief pillars supporting molecular biology research. Lay a solid foundation for your research with Thermo Fisher Scientific’s suite of products that aid nucleic acid electrophoresis and blotting.


DNA electrophoresis

DNA double helix on a dark background

Isolate, quantify, and purify DNA fragments with highly acclaimed Invitrogen products for DNA electrophoresis including devices, gels, stains, ladders, markers, buffers, and reagents.

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Southern blotting

DNA fragments separated on a gel for Southern blotting

Detect the identity, size, and abundance of target DNA sequences with superior performing Invitrogen products including membranes, probes, and buffers.

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Thermo Scientific DNA electrophoresis

Nucleic acid fragments separated on a gel submerged in a buffer

Conduct routine DNA electrophoresis with reliable Thermo Scientific products including GeneRuler ladders, TopVision agarose, loading dyes, and buffers.

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RNA electrophoresis

RNA strands on a blue background

Isolate, quantify, and purify RNA fragments with highly acclaimed Invitrogen products for denaturing and non-denaturing RNA electrophoresis.

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Northern blotting

RNA bands on a gel

Immobilize and detect the identity, size, and abundance of target RNA sequences with highly acclaimed Invitrogen products for northern blotting.

Discover products for northern blotting

Thermo Scientific RNA electrophoresis

Illustration of tRNA enclosed within a blue cube

Reliable products for routine RNA electrophoresis including RiboRuler RNA ladders, TopVision agarose, loading dyes, and buffers.

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Nucleic acid electrophoresis systems

Thermo Fisher Scientific offers traditional and precast gel nucleic acid electrophoresis systems. The precast E-Gel systems come with a gel running platform integrated with an imaging device. These systems are suitable for both standard and high-throughput electrophoresis. The traditional Owl systems are used for casting and running micro, mini, and wide gels.

E-Gel Precast Agarose Gel Electrophoresis System

Power Snap instrument, base module, and precast gel cassette

The Invitrogen E-Gel precast agarose gel electrophoresis systems are bufferless agarose gel electrophoresis systems with ready-to-use precast agarose gel cassettes with in-gel stain. The E-Gel precast agarose electrophoresis system simplifies the electrophoresis workflow, and it is ideal for analyzing PCR products, restriction digests, and plasmid preparations.

Get to know the E-Gel system

Owl Electrophoresis Systems

Illustration of DNA bands on a gel

Products for conventional horizontal (agarose) or vertical (polyacrylamide) gel electrophoresis including tanks, chambers, casters, plates, spacers, combs, power supplies, and other accessories.

Get to know the Owl systems


Nucleic acid electrophoresis products
Explore Thermo Fisher Scientific’s suite of products for all your electrophoresis needs.

Nucleic acid electrophoresis education
Learn about gel electrophoresis basics, workflow, considerations, applications, and troubleshooting for separation and analysis of nucleic acids.

DNA and RNA protocols
Find easy-to-follow protocols for everyday experiments, including agarose protocols and mRNA protocols.


Nucleic acid purification and analysis support center
Find tips, troubleshooting help, and resources for your nucleic acid purification and analysis applications.

Contact us
For additional questions, reach out to our Technical Application Scientists.

For Research Use Only. Not for use in diagnostic procedures.

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