DNA electrophoresis is a standard laboratory technique used to identify, quantify, and purify DNA fragments. DNA electrophoresis involves loading DNA samples into the wells of an agarose or acrylamide gel and subjecting it to an electric field.
DNA fragments have a net negative charge; when subjected to an electric field, the negatively charged nucleic acid fragments migrate towards the positive electrode. The length of DNA fragments is a primary factor that influences the rate of migration—shorter DNA fragments travel faster through the gel matrix than longer fragments. Therefore, DNA electrophoresis results in separation—or resolution—of DNA fragments based on size.
Thermo Fisher Scientific provides high-quality gels, reagents, and devices to support the DNA electrophoresis workflow.
To determine the size and mass of double stranded DNA fragments in agarose and polyacrylamide gels, Thermo Fisher Scientific offers a broad selection of DNA ladders and markers ranging between 10 bp to 50 kb. The ladders are made from chromatographically purified DNA fragments and are available in standard and ready-to-use formats.
The series of UltraPure buffers and reagents, made from the high purity biochemicals, are designed for optimal performance of DNA gel electrophoresis.
Thermo Scientific DNA electrophoresis reagents include DNA ladders, buffers, dyes, and gel components. These laboratory staples are known for their purity and performance.
Thermo Scientific Owl Gel Electrophoresis systems offer horizontal and vertical gel casting running chambers and related accessories for routine electrophoresis including tanks, chambers, casters, plates, spacers, combs, power supplies, and other accessories.
The all-in-one Invitrogen E-Gel Power Snap Electrophoresis System is designed for fast and convenient E-Gel agarose gel electrophoresis, from DNA sample loading to gel image. With dry precast E-Gel agarose gel technology, you can run DNA samples in as little as 10 minutes and observe sample separation in real time. It is the only benchtop system that seamlessly integrates DNA sample separation and gel imaging into one workflow.
Nucleic acid electrophoresis products
Explore Thermo Fisher Scientific’s suite of products for all your electrophoresis needs.
Nucleic acid electrophoresis education
Learn about gel electrophoresis basics, workflow, considerations, applications, and troubleshooting for separation and analysis of nucleic acids.
DNA and RNA protocols
Find easy-to-follow protocols for everyday experiments, including agarose protocols and mRNA protocols.
Nucleic acid purification and analysis support center
Find tips, troubleshooting help, and resources for your nucleic acid purification and analysis applications.
For additional questions, reach out to our Technical Application Scientists.
For Research Use Only. Not for use in diagnostic procedures.