Molecular Probes fluorescent nucleic acid gel stains—SYBR Gold, SYBR Green I, SYBR Green II, and SYBR Safe dyes—are highly sensitive reagents for staining DNA in electrophoresis gels. These gel stains provide greater sensitivity, with lower background fluorescence, than the conventional ethidium bromide gel stain.

In addition, SYBR Safe DNA gel stain exhibited very low mutagenicity compared to ethidium bromide, when tested by an independent, licensed testing laboratory, and it is not classified as hazardous waste or as a pollutant under U.S. federal regulations.

Which DNA stain is right for you?

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  Detection of nucleic acids in agarose gels & CsCl gradients Safer, smarter alternative to EtBr Ultimate Sensitivity for capillary electrophoresis & real-time PCR Ultimate sensitivity for DNA detection
  UltraPure Ethidium Bromide 
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SYBR Safe

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SYBR Green I SYBR Gold
Top seller        
Sensitivity - dsDNA Sensitive 
(1 ng)
Sensitive 
(3 ng)
Highly Sensitive 
(>60 pg)
Ultra Sensitive 
(>25 pg)
Nonhazardous/ 
Environmentally-Friendly
       
Available as Ready to Use        
Recommended for Gel Electrophoresis        
Recommended for ssDNA        
Improved Cloning Efficiency / Avoid UV-Induced Nicked DNA        
Package sizes
  • 10 mL
  • 0.4 mL
  • 1 L (ready to use)
  • 4 L (ready to use)
  • 0.5 mL
  • 1 mL
  • 20 x 50 µL
  • 0.5 mL