Invitrogen Molecular Probes fluorescent nucleic acid gel stains—SYBR Gold, SYBR Green I, SYBR Green II, and SYBR Safe dyes—are highly sensitive reagents for staining DNA in electrophoresis gels. These gel stains provide greater sensitivity, with lower background fluorescence, than the conventional ethidium bromide gel stain.
In addition, SYBR Safe DNA gel stain exhibited very low mutagenicity compared to ethidium bromide, when tested by an independent, licensed testing laboratory, and it is not classified as hazardous waste or as a pollutant under U.S. federal regulations.