Tools and resources to support TALEN and CRISPR applications

Genome editing has emerged as one of humanity’s most powerful technologies in the pursuit of a greater understanding of human health and disease. Less expensive and relatively easy to design, the next generation of gene editing tools is now allowing researchers to target almost any gene for modification in a highly specific and reliable way. ​​

In this educational web hub, you will find a variety of tools and resources to fully support your understanding of gene editing techniques and methods. Learn all you need to know in order to overcome existing hurdles and design successful gene editing experiments, whether for TALEN or CRISPR applications.

Explore free downloads, watch how-to tutorials, gain insights from expert interviews and scientific articles, watch gene editing videos and webinars—and more.

Learn more about gene editing techniques—download gene editing handbook for TALEN and CRISPR basics, CRISPR infographics, and more

Infographic

CRISPR for Therapeutics

Discover how CRISPR-Cas9 is driving a new generation of cell engineering for cell-based therapies and key considerations for selecting Cas9 reagents and suppliers.

Download infographic


Watch TALEN and CRISPR Cas9 tutorials—Gene editing methods, step-by-step CRISPR training and more

Video

A step-by-step workflow for a knock-out experiment in an adherent cell line

In this tutorial video, we demonstrate the process of conducting a HPRT gene knock-out experiment in a HEK293 adherent cell line.

Video

A step-by-step workflow for a knock-in experiment in an adherent cell line

In this tutorial video, we demonstrate the process of conducting a beta actin gene knock-in in a HEK293 adherent cell line.

Video

A step-by-step workflow for a knock-out experiment in iPSCs

In this tutorial video, we demonstrate the process of conducting a gene knock-out experiment in induced pluripotent stem cells.

Video

A step-by-step workflow for a knock-out experiment in T cells

In this tutorial video, we demonstrate the process of conducting a PDCD1 gene knock-out in T cells.


Get insights on gene editing techniques from industry leaders

Video

CRISPR-Cas9: A transformative tool for treating debilitating genetic disease

Dr. Evangelos Kiskinis, Assistant Professor of Neurology and Neuroscience at Northwestern University

 

Video

How CRISPR provides a unique opportunity to generate rare disease avatars

Dr. Sergio Casas-Tintó, Head of Drosophila Models, Human Disease Unit, Institute for Rare Diseases Research (IIER)

 

Promotional banner with article title and contributor headshot

Article

Revolutionizing drug discovery: The role of CRISPR gene editing in target validation

Dr. Panos Zalmas, Head of the Open Targets Validation Lab, Wellcome Sanger Institute

Read article

Promotional banner with article title and contributor headshot

Article

CRISPR-generated CAR-T cells: A new frontier in the treatment of solid tumors

Dr. Krishanu Saha, Associate Professor at the University of Wisconsin-Madison

Read article


Watch TALEN and CRISPR webinars

Screenshot showing the webinar title slide

Webinar

Gene editing in stem cells—Methods and considerations

Hemanta Sarmah, Postdoctoral Research Scholar at Columbia Stem Cell Initiative

Watch now


Featured gene editing videos


Featured products to support gene editing methods and applications


For Research Use Only. Not for use in diagnostic procedures.