Browse learning materials by resource collection

Within the Genome Editing Learning Center, the Resource Library is where you can connect to all our different educational, technical, application, and other learning materials by resource collection. This includes webinars & videos, application notes & poster presentations, and publications.

To browse learning content by genome editing application subtopic, visit the main Genome Editing Learning Center home.

Related resources

Learning center home

Resource library collections

Resource library collections

Genome Editing Videos & Webinars

From general overviews of CRISPR and TALEN-based genome editing techniques and experimental design best practices to specific applications including cell engineering and knock-in/-out strategies, our collection of videos and webinars is designed to help you maximize your success using these technologies.

Genome Editing Support Center

Browse applications within the Genome Editing Support Center for product and general technical support. Includes resources and tips for getting started, and troubleshooting help all in one location.

Search all learning center resources

No records were found matching your criteria

Type Name Genome editing technology
Application note Delivery solutions for immune cells  CRISPR-Cas9
Application note Improve genome editing outcomes in biologically relevant cell models CRISPR-Cas9, TALEN
Application note Using Sanger sequencing to facilitate CRISPR and TALEN-mediated genome editing workflows CRISPR-Cas9, TALEN
FAQs CRISPR-based genome editing—Getting Started FAQs CRISPR-Cas9
FAQs CRISPR-based genome editing—Troubleshooting FAQs CRISPR-Cas9
FAQs TALEN-based genome editing—Getting Started FAQs TALEN
FAQs TALEN-based genome editing—Troubleshooting FAQs TALEN
Infographic Genome Editing With Engineered Nucleases CRISPR-Cas9
Infographic The Evolution of Genome Editing CRISPR-Cas9
Protocol Embryo Microinjection With CRISPR-Cas9 in Mice and Zebrafish CRISPR-Cas9
Protocol CRISPR-Cas9 Genome Editing In Human Induced Pluripotent Stem Cell CRISPR-Cas9
Publication (2016) Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNA CRISPR-Cas9
Publication (2016) Improved delivery of Cas9 protein/gRNA complexes using lipofectamine CRISPRMAX  CRISPR-Cas9
Publication (2015) Rapid and highly efficient mammalian cell engineering via Cas9 protein transfection.  CRISPR-Cas9
Publication (2015) Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.  CRISPR-Cas9
Publication (2015) Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease  CRISPR-Cas9
Publication (2015) Efficient Intracellular Delivery of Native Proteins  CRISPR-Cas9
Publication (2015) CRISPR/Cas9 nuclease cleavage combined with Gibson assembly for seamless cloning.  CRISPR-Cas9
Publication (2015) Engineered CRISPR-Cas9 nucleases with altered PAM specificities  CRISPR-Cas9
Publication (2015) Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers  CRISPR-Cas9
Publication (2015) Digienome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells  CRISPR-Cas9
Publication (2015) In vivo genome editing using Staphylococcus aureus Cas9  CRISPR-Cas9
Publication (2015) Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors  CRISPR-Cas9
Publication (2015) Multiplex conditional mutagenesis using transgenic expression of Cas9 and sgRNAs  CRISPR-Cas9
Publication (2015) Chemically modified guide RNAs enchance CRISPR-Cas genome editing in human primary cells  CRISPR-Cas9
Publication (2015) A Cas9–guide RNA complex preorganized for target DNA recognition  CRISPR-Cas9
Publication (2014) Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases  CRISPR-Cas9
Publication (2014) Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects  CRISPR-Cas9
Publication (2014) DNA interrogation by the CRISPR RNA-guided endonuclease Cas9  CRISPR-Cas9
Publication (2014) Programmable RNA recognition and cleavage by CRISPR/Cas9  CRISPR-Cas9
Publication (2014) Landscape of target: guide homology effects on Cas9-mediated cleavage  CRISPR-Cas9
Publication (2014) Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA  CRISPR-Cas9
Publication (2014) Improving the specificity and efficacy of CRISPR/CAS9 and gRNA through target specific DNA reporter  CRISPR-Cas9
Publication (2014) Crystal structure of Cas9 in complex with guide RNA and target DNA  CRISPR-Cas9
Publication (2014) Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo   CRISPR-Cas9
Publication (2014) Guide RNA functional modules direct Cas9 activity and orthogonality  CRISPR-Cas9
Publication (2014) Protospacer Adjacent Motif (PAM)-Distal Sequences Engage CRISPR Cas9 DNA Target Cleavage  CRISPR-Cas9
Publication (2014) Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool  CRISPR-Cas9
Publication (2014) GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases  CRISPR-Cas9
Publication (2014) Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation  CRISPR-Cas9
Publication (2014) Improving CRISPR-Cas nuclease specificty using truncated guide RNAs  CRISPR-Cas9
Publication (2014) Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease  CRISPR-Cas9
Publication (2014) High-throuput screening of a CRISPR/Cas9 library for functional genomics in human cells  CRISPR-Cas9
Publication (2014) CRISPR-mediated direct mutation of cancer genes in the mouse liver  CRISPR-Cas9
Publication (2014) Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex  CRISPR-Cas9
Publication (2014) Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation  CRISPR-Cas9
Publication (2014) High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zince finger nucleases or CRISPR/Cas9 nickase pairs  CRISPR-Cas9
Publication (2014) CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences  CRISPR-Cas9
Publication (2014) Genome-Scale CRISPR-Cas9 knockout screening in human cells  CRISPR-Cas9
Publication (2014) Genetic screens in human cells using the CRISPR-Cas9 system  CRISPR-Cas9
Publication (2014) Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells  CRISPR-Cas9
Publication (2014) Dimeric CRISPR RNA-guided FokI nucleases for efficient genome editing  CRISPR-Cas9
Publication (2014) CasOT: a genome-wide Cas9/gRNA off-target searching tool  CRISPR-Cas9
Publication (2014) Classification and evolution of type II CRISPR-Cas systems  CRISPR-Cas9
Publication (2014) Development and applications of CRISPR-Cas9 for genome engineering  CRISPR-Cas9
Publication (2014) Cut site selection by the two nuclease domains of the Cas9 RNA-guided endonuclease  CRISPR-Cas9
Publication (2014) Synthetic TAL effectors for targeted enhancement of transgene expression in plants  TALEN
Publication (2013) Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes  CRISPR-Cas9
Publication (2013) Precise and Heritable Genome Editing in Evolutionarily Diverse Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and Deletions  CRISPR-Cas9
Publication (2013) Targeted Heritable Mutation and Gene Conversion by Cas9-CRISPR in Caenorhabditis elegans  CRISPR-Cas9
Publication (2013) Transgene-Free Genome Editing in Caenorhabditis elegans Using CRISPR-Cas  CRISPR-Cas9
Publication (2013) The CRISPR/Cas System mediates efficient genome engineering in Bombyx mori  CRISPR-Cas9
Publication (2013) Highly Efficient Genome Modifications Mediated by CRISPR/Cas9 in Drosophila  CRISPR-Cas9
Publication (2013) Efficient genome editing in zebrafish using a CRISPR-Cas system  CRISPR-Cas9
Publication (2013) Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish  CRISPR-Cas9
Publication (2013) Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system  CRISPR-Cas9
Publication (2013) Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System  CRISPR-Cas9
Publication (2013) Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos  CRISPR-Cas9
Publication (2013) Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis  CRISPR-Cas9
Publication (2013) Effective gene targeting in rabbits using RNA-guided Cas9 nucleases  CRISPR-Cas9
Publication (2013) Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems  CRISPR-Cas9
Publication (2013) Heritable gene targeting in the mouse and rat using a CRISPR-Cas system  CRISPR-Cas9
Publication (2013) Generation of gene-modified mice via Cas9/RNA-mediated gene targeting  CRISPR-Cas9
Publication (2013) Heritable Gene Knockout in Caenorhabditis elegans by Direct Injection of Cas9–sgRNA Ribonucleoproteins  CRISPR-Cas9
Publication (2013) High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity  CRISPR-Cas9
Publication (2013) Phylogeny of Cas9 determines functional exchange ability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems  CRISPR-Cas9
Publication (2013) Genotyping with CRISPR-Cas-derived RNA-guided endonucleases  CRISPR-Cas9
Publication (2013) crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus  CRISPR-Cas9
Publication (2013) Programmable DNA cleavage in vitro by Cas9  CRISPR-Cas9
Publication (2013) Genome engineering in cerevisiae using CRISPR-Cas systems  CRISPR-Cas9
Publication (2013) RNA-guided editing of bacterial genomes using CRISPR-Cas systems  CRISPR-Cas9
Publication (2013) Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system  CRISPR-Cas9
Publication (2013) Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9  CRISPR-Cas9
Publication (2013) Targeted genome modification of crop plants using a CRISPR-Cas system  CRISPR-Cas9
Publication (2013) Heritable genome editing in C. elegans via a CRISPR-Cas9 system  CRISPR-Cas9
Publication (2013) CRISPR/Cas9-Targeted Mutagenesis in Caenorhabditis elegans  CRISPR-Cas9
Publication (2013) Heritable Custom Genomic Modifications in Caenorhabditis elegans via a CRISPR–Cas9 System  CRISPR-Cas9
Publication (2013) Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease  CRISPR-Cas9
Publication (2013) Multiplex Genome Engineering Using CRISPR/Cas Systems  CRISPR-Cas9
Publication (2013) RNA-programmed genome editing in human cells  CRISPR-Cas9
Publication (2013) Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease  CRISPR-Cas9
Publication (2013) CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering  CRISPR-Cas9
Publication (2013) High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells  CRISPR-Cas9
Publication (2013) DNA targeting specificity of RNA-guided Cas9 nucleases  CRISPR-Cas9
Publication (2013) Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus  CRISPR-Cas9
Publication (2013) CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity  CRISPR-Cas9
Publication (2013) Orthogonal Cas9 proteins for RNA-guided gene regulation and editing  CRISPR-Cas9
Publication (2013) Efficient generation of large-scale genome-modified mice using gRNA and Cas9 endonuclease  CRISPR-Cas9
Publication (2013) Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity  CRISPR-Cas9
Publication (2013) Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression  CRISPR-Cas9
Publication (2013) Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system  CRISPR-Cas9
Publication (2013) CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes  CRISPR-Cas9
Publication (2013) Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice  CRISPR-Cas9
Publication (2013) Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA  CRISPR-Cas9
Publication (2013) Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis  CRISPR-Cas9
Publication (2013) The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems  CRISPR-Cas9
Publication (2013) High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.   TALEN
Publication (2012) A CRISPR/Cas system mediates bacterial innate immune evasion and virulence  CRISPR-Cas9
Publication (2012) Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria  CRISPR-Cas9
Publication (2012) RNA-Guided Human Genome Engineering via Cas9  CRISPR-Cas9
Publication (2012) A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity  CRISPR-Cas9
Publication (2012) Obligate Ligation-Gated Recobmination (ObLiGaRe): Custom-designed nuclease-mdediated targeted integration through nonhomologous end joining  CRISPR-Cas9
Publication (2011) The Streptococcus thermophilus CRISPR/Cas system provides immunity in Eschrichia coli  CRISPR-Cas9
Publication (2011) CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III  CRISPR-Cas9
Publication (2011) A TALE nuclease architecture for efficient genome editing   TALEN
Publication (2011) Assembly of custom TALE-type DNA binding domains by modular cloning  TALEN
Publication (2011) Genetic engineering of human pluripotent cells using TALE nucleases  TALEN
Publication (2011) Transcriptional Activators of Human Genes with Programmable DNA-Specificity  TALEN
Publication (2011) Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting  TALEN
Publication (2011) Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription  TALEN
Publication (2009) Short motif sequences determine the targets of prokarytoic CRISPR defence system  CRISPR-Cas9
Publication (2009) Breaking the code of DNA binding specificity of TAL-type III effectors  TALEN
Publication (2009) A simple cipher governs DNA recognition by TAL effectors  TALEN
Publication (2007) CRISPR provides acquired resistance against viruses in prokaryotes  CRISPR-Cas9
Publication (2005) Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin  CRISPR-Cas9
Resource guide CRISPR-Cas9 Protein for Genome Editing—Getting Started Guide  CRISPR-Cas9
Resource guide Genome Editing Resource Guide CRISPR-Cas9, TALEN
Tips & tricks Top 10 Tips and Tricks: Designing a knock-in experiment CRISPR-Cas9, TALEN
Tips & tricks Top 10 Tips and Tricks: Improve your genomic cleavage detection (GCD) assay CRISPR-Cas9, TALEN
Tips & tricks Top 10 Tips and Tricks: Genome cleavage selection (GCS)–based screening CRISPR-Cas9, TALEN
Tips & tricks Top 10 Tips and Tricks: TAL effector-mediated genome editing TALEN
Tips & tricks Top 10 Tips and Tricks: Successful CRISPR guide RNA synthesis CRISPR-Cas9, TALEN
Video Genome editing video collection CRISPR-Cas9
Webinar Genome editing webinars CRISPR-Cas9, TALEN