Introducing the first-to-market, third party certified cleanroom compatible CO2 incubator. Suitable for ISO Class 5 and Good Manufacturing Practices (GMP) grade A/B environments. Thermo Scientific Heracell Vios CR CO2 Incubators and Thermo Scientific Forma Steri-Cycle CR CO2 Incubators feature an active particle control system and demonstrated compatibility with commonly used cleanroom cleaning methods, making it the perfect fit for your cleanroom suite or GMP production environment.

Cleanroom compatible CO2 incubators

Cleanroom certified

Through rigorous testing, the Heracell Vios CR / Forma Steri-Cycle CR incubators have successfully achieved ISO class 5 compatibility for the considered particle sizes in both standard operating and sterilization modes. 

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Robust and easy to clean

In cleanroom environments, CO2 incubators need to be robust enough to withstand the thorough cleaning procedures required. The Vios CR / Steri-Cycle CR incubator exterior is easier to clean and maintain.

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GMP documentation package

The industrial design has been tested and independently validated to ensure it meets the needs of evolving cleanroom and GMP production environments. A complete factory documentation package is included.

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Watch the video to learn more about certified cleanroom compatible CO2 incubators

 

 

Choose the CO2 incubator for your cleanroom

 Heracell Vios 160i CRHeracell Vios 250i CR
 
Vios 250i CR
DescriptionAdvanced incubator design for high value cells Advanced large capacity for high value cells and high throughput labs
Capacity165 L (5.8 cu. ft.)255 L (9.0 cu. ft.)
Chamber typeDirect heatDirect heat
Door swingRight hingedRight hinged
Exterior materialBrushed 304 L stainless steelBrushed 304 L stainless steel
Choose interior304 Stainless steel ›
100% copper ›
Cell Locker System (configurable system) ›
304 Stainless steel ›
100% copper ›
 
SterilizationSteri-Run (180°)Steri-Run (180°)
IP rating IP54 ratedIP54 rated
In-chamber HEPA filtration ISO Class 5 interior conditionsISO Class 5 interior  conditions
Active particle control systemISO Class 5 GMP grade A/B external conditionsISO Class 5 GMP grade A/B external conditions
Airlfow technologyTHRIVE:  THRIVE:  
CO2 sensorsIR180SiIR180Si
O2 controlOptional 1-21% or 5-90%Optional 1-21% or 5-90%
HumidityCovered integrated reservoir with easy drainingCovered integrated reservoir with easy draining
User interfaceiCAN touch screeniCAN touch screen
Documentation packageIncludedIncluded
Data output4-20 mA standard4-20 mA standard
 Forma Steri-Cycle 160i CRForma Steri-Cycle 250i CR
 Forma 160i CRForma 250i CR
DescriptionAdvanced incubator design for high value cells Advanced large capacity for high value cells and high throughput labs
Capacity165 L (5.8 cu. ft.)255 L (9.0 cu. ft.)
Chamber typeDirect heatDirect heat
Door swingRight hingedRight hinged
Exterior materialBrushed 304 L stainless steelBrushed 304 L stainless steel
Choose interior304 Stainless steel ›
100% copper ›
Cell Locker System (configurable system) ›
304 Stainless steel ›
100% copper ›
 
SterilizationSteri-Run (180°)Steri-Run (180°)
IP Rating IP54 ratedIP54 rated
In-chamber HEPA filtration ISO Class 5 interior conditionsISO Class 5 interior conditions
Active particle control systemISO Class 5 GMP grade A/B external conditionsISO Class 5 GMP grade A/B external conditions
Airlfow technologyTHRIVETHRIVE 
CO2 sensorsIR180SiIR180Si
O2 controlOptional 1-21% or 5-90%Optional 1-21% or 5-90%
HumidityCovered integrated reservoir with easy drainingCovered integrated reservoir with easy draining
User interfaceiCAN touch screeniCAN touch screen
Documentation PackageIncludedIncluded
Data output4-20 mA standard4-20 mA standard
 Heracell Vios 160i CRHeracell Vios 250i CR
 
Vios 250i CR
DescriptionAdvanced incubator design for high value cells Advanced large capacity for high value cells and high throughput labs
Capacity165 L (5.8 cu. ft.)255 L (9.0 cu. ft.)
Chamber typeDirect heatDirect heat
Door swingRight hingedRight hinged
Exterior materialBrushed 304 L stainless steelBrushed 304 L stainless steel
Choose interior304 Stainless steel ›
100% copper ›
Cell Locker System (configurable system) ›
304 Stainless steel ›
100% copper ›
 
SterilizationSteri-Run (180°)Steri-Run (180°)
IP rating IP54 ratedIP54 rated
In-chamber HEPA filtration ISO Class 5 interior conditionsISO Class 5 interior  conditions
Active particle control systemISO Class 5 GMP grade A/B external conditionsISO Class 5 GMP grade A/B external conditions
Airlfow technologyTHRIVE:  THRIVE:  
CO2 sensorsIR180SiIR180Si
O2 controlOptional 1-21% or 5-90%Optional 1-21% or 5-90%
HumidityCovered integrated reservoir with easy drainingCovered integrated reservoir with easy draining
User interfaceiCAN touch screeniCAN touch screen
Documentation packageIncludedIncluded
Data output4-20 mA standard4-20 mA standard
 Forma Steri-Cycle 160i CRForma Steri-Cycle 250i CR
 Forma 160i CRForma 250i CR
DescriptionAdvanced incubator design for high value cells Advanced large capacity for high value cells and high throughput labs
Capacity165 L (5.8 cu. ft.)255 L (9.0 cu. ft.)
Chamber typeDirect heatDirect heat
Door swingRight hingedRight hinged
Exterior materialBrushed 304 L stainless steelBrushed 304 L stainless steel
Choose interior304 Stainless steel ›
100% copper ›
Cell Locker System (configurable system) ›
304 Stainless steel ›
100% copper ›
 
SterilizationSteri-Run (180°)Steri-Run (180°)
IP Rating IP54 ratedIP54 rated
In-chamber HEPA filtration ISO Class 5 interior conditionsISO Class 5 interior conditions
Active particle control systemISO Class 5 GMP grade A/B external conditionsISO Class 5 GMP grade A/B external conditions
Airlfow technologyTHRIVETHRIVE 
CO2 sensorsIR180SiIR180Si
O2 controlOptional 1-21% or 5-90%Optional 1-21% or 5-90%
HumidityCovered integrated reservoir with easy drainingCovered integrated reservoir with easy draining
User interfaceiCAN touch screeniCAN touch screen
Documentation PackageIncludedIncluded
Data output4-20 mA standard4-20 mA standard

Explore the Vios Cleanroom Incubators

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vios-160i-cr-incubator

Heracell Vios 160i CR CO2 Incubator

360-degree, spin, zoom, rotate, discover and interact with the 165L version of this cleanroom-compatible CO2 incubator.

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vios-250i-cr-incubator

Heracell Vios 250i CR CO2 Incubator

360-degree, spin, zoom, rotate, discover and interact with the 255L version of this cleanroom-compatible CO2 incubator.

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Learn about cleanroom requirements, sources of particles and risks, what it takes to be a GMP certified incubator, and how different incubators produce very different culture conditions.

Watch webinar


Key Features

Cleanroom-ISO-GMP-stamp

Cleanroom certified

Responding to the rising demand for proven cleanroom compatibility, we have met the need with the first active particle control system designed for a CO2 incubator. This innovative technology controls and captures particulates. Air throughout the casing is directed through a HEPA filter in the rear to assure no disruption to the cleanroom environment. This design is independently validated and Certified for ISO Class 5 and GMP Grade A/B environments.

CR-Vios-160back-model

Robust and easy to clean

  • Brushed 304 stainless steel exterior is compatible with STERISdry non-condensing VHP and 3% manual wipe hydrogen peroxide cleaning methods typically used in cleanroom environments.
  • PLUS Sealed exterior casing includes silicone sealed electronics and welded door to contain any particulate risk.
  • PLUS IP54 rated componentry protects electronics from dust and is resistant to water spray from any direction.
Cleanroom-documentation

Documentation package including:

  • Regulatory certificates
  • Declaration of Conformity (CE) with EU law, CSA and QMS Certificates
  • Recommended protocols
  • User-replaceable parts and consumables lists
  • Product-specific factory documentation and specification
  • Certificates of conformance, calibration, and technical specifications
  • 3rd party certificate of compatibility with ISO Class 5 and GMP Grade A/B cleanroom environments

Shelving Systems for Heracell Vios CR 250i CO2 Incubators

 

 

Designed to maximize incubator space.

 

 

 

 


As you scale out your cell therapy manufacturing, the incubator you have come to trust can now adjust with you. To match your changing needs, our special shelving system options offer additional capacity and/or improved access for specialized cell culture vessels such as ScaleReady's G-Rex® 500M-CS bioreactors (by Wilson Wolf) or Thermo Scientific Nunc Cell Factory Systems.

These dedicated shelving systems are available as separate accessories. Each offers several advantages as you enter the cell expansion stage using larger cell culture vessels.


Stainless steel reinforced shelves

Available as accessory

Self-installation and retrofittable

Fit more ScaleReady's G-Rex® bioreactors into your incubator

Download flyer

Standard shelving: 4 x G-Rex® 500M-CS

Special shelving system: 10 x G-Rex® 500M-CS

Heracell Vios CR 250i and Vios 250i
Incubator Accessories
Vessel TypeAdvantagesAction
Shelving system for up to 10x G-Rex® 500M-CS150% more capacity compared to standard shelvingRequest quote ›
Shelving system for 6x Nunc Cell Factory 10 systemsEasy access, clearance for air filterContact me when available ›
Shelving system for 10x Nunc Cell Factory 4 systemsAccommodates 1 more Cell Factory system, easy access, clearance for air filtersContact me when available ›


Embark on the remarkable

Dedicated equipment for cell and gene therapy manufacturing

See all options ›

Style Sheet for Global Design System