Ultra-Low Temperature Freezer Features

Reliable, durable, energy efficient and secure storage for your precious samples.

Quality Assured

We understand the pivotal role reliable and high-quality lab equipment plays in your research endeavors, that’s why our ULT freezers are carefully engineered to meet the exacting demands of modern research environments. Our commitment to quality assurance is at the core of our ULT innovation. 


We are dedicated to supporting our customers’ needs, continuously improving our processes, and empowering our staff to help ensure we deliver exceptional ultra-low temperature freezers. From concept to post-production delivery, reliability remains at the forefront.


TSX Universal Series ULTs represent our most robust design to date, incorporating insights from over 80 years of experience to enhance every aspect of the system. From sealed system and cabinet construction to software architecture and electrical components, each element of the TSX Universal ULT platform has undergone significant testing to ensure it meets our high-quality standards.



12 years
Reliability test, 16+ probe location performance test, and 100% end of life test Combined days of continuous reliability testing in the field and laboratory environments Industry-leading warranty coverage

Industry-leading warranty 

We stand behind our products with confidence, and we take pride in providing an industry-leading warranty that sets us apart from any other ULT supplier in the market. When you purchase our ULT freezers, you can have peace of mind knowing they come with a 12-year warranty.


Measurably High-Performance

Universal V-Drive Technology


The new TSX Universal Series ULT freezers feature the innovative Universal Variable Drive (V-Drive) technology, marking a significant advancement in performance and energy efficiency. Unlike standard compressors that operate in a binary full-power or nothing mode, the Universal V-Drive adjusts its speed variably to achieve optimal cooling capacity while maximizing energy efficiency.

Through updates to our variable speed compressors, improvements to intelligent algorithms, and optimization of hardware with our new Universal V-Drive cooling technology, users can now experience universally better performance across all metrics compared to the previous generation TSX Series ULT freezers, demonstrated in the below table.

A new benchmark for performance metrics

Thanks to our new and innovative Universal V-Drive technology, which is available on the Universal ULT freezers platform, users will experience tighter performance across all measurements. Setting a new benchmark for performance.


The table below compares the performance data between the new TSX Universal Series ULT freezers and the previous generation TSX Series ULT freezers. 


Smarter cabinet design


With over 80 years of experience in manufacturing ultra-low temperature freezers, you can be sure that every detail of our freezer cabinets has been optimized for performance. Starting with the selection of only top materials, our freezers are constructed of rugged galvaneel or optional stainless steel interiors. Stainless steel shelves are both adjustable and reinforced to hold up to 125 pounds each. Thoughtful compartmentalization maximizes storage capacity and utilizes inner doors that reduce frost and ambient temperature impact. Outer doors and panels achieve exceptional R-value insulation rating via vacuum panels with water blown foam insulation. Airtight closures are assured with triple point seals around door apertures. Finishing touches include integrated control panels, easy access to filter maintenance compartments and castors that make day-to-day use intuitive and easy. And it’s all delivered in a package that optimizes sample storage per square foot and cooling capacity. 

Greener by Design

We leverage the power of innovation to positively contribute to a healthier world, which includes reducing the environmental impact of our products and packaging—from design to end of life. By incorporating environmental sustainability principles into each design step, we can better understand and reduce the environmental impact of our products early in the design process, ultimately delivering on our commitment to achieve net-zero emissions by 2050 while helping customers advance their sustainability goals.

Less hazardous

Less waste

More energy efficient

Responsibly packaged

Extended life
We use natural refrigerants and insulation with extremely low GWP & ODP levels, far lower than current regulatory requirements. Asheville, NC, is a Zerowaste to Landfill site and our lab freezers are manufactured with 60-70% recycled steel. All ULTs are ENERGY STAR certified, providing substantial energy savings. We use locally sourced and 100% by-weight recycled corrugate packaging and manufacture regionally to reduce transport emissions. Our ULTs offer a 12-year industryleading warranty, helping minimize the production, shipping, and disposal of units each year.

ENERGY STAR-certified

By choosing our ULTs, labs can feel confident knowing that our solutions operate at industry-leading low energy levels, helping to contribute to a greener footprint while optimizing operational costs. Trust in our commitment to environmental sustainability and innovation to propel your research endeavors forward.


Transparency in sustainability

We believe it should be easy to make informed purchasing decisions when looking for more sustainable products. By participating in the ACT label program, run by the non-profit organization My Green Lab, we can provide easy-to-use information about our ULTs environmental impact.


Future-ready for the connected lab

Remote monitoring

Enhance sample security and streamline asset management with remote monitoring solutions. Our secure platforms provide cutting-edge asset management, predictive analytics and 24/7 remote monitoring to help ensure the integrity of products and samples vital to the work you do.  Our professional-grade solutions will transform your static lab equipment into vital, data producing assets so you can work smarter, not harder.


Learn more about Connected Solutions

Connectivity Hardware

Explore our range of connectivity hardware, designed with labs of the future in mind. You can now transform static lab equipment into smart technology capable of delivering actionable information to help enhance sustainability, increase productivity and efficiency and maintain the integrity of both equipment and samples.

DeviceLink Connect – remote monitoring

Leveraging the Thermo Fisher Connect Platform, DeviceLink Connect hardware provides peace of mind by enabling you to oversee your equipment from anywhere, at any time via the InstrumentConnect app or directly on your PC.

Smart-Vue Pro – regulatory compliance

Smart-Vue Pro stands out as a widely-deployed remote monitoring solution for sample management that helps ensure total compliance for regulatory agencies and qualification for GxP protocols.

Insight – asset performance

InSight Analytics saves time and money by offering data-driven product insights to help guide operations and purchasing decisions. Decrease downtime and improve sustainable practices with predictive health data.


Optimized storage space

Thermo Scientific ULT freezers utilize an advanced vacuum-insulated cabinet walls to increase interior space, with a standardized rack, tray and box storage configuration that allows for optimum storage in the smallest possible footprint. Choose from sizes that store 300, 400, 500, 600, or 700 2-inch boxes.

Browse storage systems and accessories

7" full capacity touch display

With the launch of the TSX Universal Series ULT freezers, we made upgrades to our 7-inch full capacitive touch display to further enhance your experience and help simplify your interactions with the unit. Below are just some of the updates we made to help improve user experience and overall lab operation.


Easy Access Warranty Registration and Manual

4 Digit PIN Access (in Full Access)

Simple Start-up Wizard

Warning and Cautions- Not Alarms and Alerts

Simplified Charts

Easy Access and Customizable Snooze

Ergonomic design

You’ll like the confidence you gain in the viability of your samples, but you may love the freezer itself once you start using it. Through years of design collaboration and testing with our customers, we’ve incorporated some notable features such as an ergonomic, smooth operating handle, well-balanced doors and intuitive, easy to see and read control panels. Our new TSX Universal ULTs operate below 44 decibels - helping reduce noise pollution in your lab.

Secure storage

Lock compatible doors enhance the security of your samples. When a standard padlock is not practical, integrated access key security system options on our ULT freezer doors allow you to define who has access to your samples and even monitor who opens the freezer door, when and how long the door is open to help ensure strict security and safe storage.

Certifications and Verifications

ENERGY STAR certified - a government backed     symbol for energy efficiency.


ACT label verified – for third-party verification of the sustainable impacts of a product, its operations, and its end of life.


Compliant with the Significant New Alternatives Policy (SNAP) program - part of the US Clean Air Act under the US Environmental Protection Agency (EPA).

cULus certified - tested to meet the safety standards of Canada and the United States by Underwriters Laboratories.


ISO Class 5.5


The TSX and TDE Series ultra-low freezers have been independently tested by Underwriters Laboratories (UL), in accordance with ISO 14644-14:2016, to meet the International Organization for Standardization (ISO) Class 5.5; operational; 0.1 μm, 0.2 μm, 0.3 μm, 0.5 μm, 1.0 μm cleanroom standard limits. This designation helps deliver innovative solutions that meet the evolving needs of the scientific and healthcare industries for sensitive cleanroom settings.


Cell and gene therapy products, including live cells, genetic materials, and viral vectors, are often highly sensitive to temperature fluctuations and contamination. Maintaining the integrity of these materials is crucial for their efficacy and safety. This designation ensures that TSX and TDE series ultra-low temperature freezers can be used in closer proximity to the workflow, preserving the quality and viability of cell and gene therapy products in controlled environments. In addition, the manufacturing of life-saving drugs, sterile preparations and biological products benefit from the safety and consistency of this series of ULT freezers. 


Having an ultra-low temperature freezer tested and designated to ISO 14644-14:2016 Class 5.5: operational; 0.1 μm, 0.2 μm, 0.3 μm, 0.5 μm, 1.0 μm provides cell and gene therapy companies with confidence in the cleanliness and control of their storage environments. It addresses key challenges related to regulatory compliance, product integrity, cross-contamination prevention, data integrity, and Good Manufacturing Practice (GMP) adherence, contributing to the safe and effective development and manufacturing of cell and gene therapies.

With five option sizes available (from 14.9cu. ft to 33.5cu ft) and three voltage options, Thermo Fisher Scientific ensures that researchers and scientists in the biopharmaceutical industry have access to a matrix of comparable models, all tested according to ISO 14644-14 and designated ISO Class 5.5; operational; 0.1 μm, 0.2 μm, 0.3 μm, 0.5 μm, 1.0 μm cleanroom standard.


Thermo Fisher Scientific is committed to delivering innovative, healthier, cleaner and safer solutions that meet the evolving needs of the scientific and healthcare industries. By obtaining ISO Class 5.5 cleanroom designation for the TSX and TDE series Ultra-Low Freezers, Thermo Fisher Scientific can now provide a full spectrum of cold storage solutions, from +5C to -86C. Manufacturing drugs, sterile preparations, and biological products. Cell and gene therapy.

  • Thermo Scientific Ultra Low Freezers tested according to ISO 14644-14 and designated ISO Class 5.5; operational; 0.1 μm, 0.2 μm, 0.3 μm, 0.5 μm, 1.0 μm
  • Large offering of solutions at ultra-low temperatures
  • Entire Cold Storage Spectrum offering (+5 to -86)
  • Five option sizes available (from 14.9cu. ft to 33.5cu ft) and three voltage options
  •  The level of classification is lower (ISO 5.5 vs competitor claims to ISO 6), and the product offering is wider (both by size configuration and temperature range) which allows flexibility in workflow.
  • Enhanced Good Manufacturing Practice (GMP) Compliance