Save time at the bench with fast, reliable Thermo Scientific Multidrop dispensers
Fill plates in seconds with excellent precision and reproducibility, helping you run tests faster and increase productivity. Compact Thermo Scientific Multidrop dispensers fit easily on the bench, and the intuitive user interface makes setup and programming a breeze. Multidrop reagent dispensers based on peristaltic pump dispensing technology utilize detachable autoclavable Multidrop cassettes for the dispensing of reagents, diluents, cells, and beads.
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Find the best tool for your dispensing needs
![]() Multidrop Combi SMART |
![]() Multidrop Combi nL |
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User interface |
On-board interface or FILLit PC software |
On-board interface or FILLit PC software |
PicoIT PC software | PicoIT PC software |
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Volumes |
0.5-2500 µl | 50 nl-50 µl | 11 pL - 20 µl or 1 nL - 200 µl |
11 pL - 20 µl or 1 nL - 200 µl |
Plate formats |
6-1536 well plates; including 96-, 384 tubes in rack format |
96-1536 well plates; including 96-, 384 tubes in rack format |
12, 24, 48, 96, 384,1536 well plate | 12, 24, 48, 96, 384 well plate |
Plate height adjustment |
Automatic | Automatic | Automatic | Manual |
Automation/robot compatible |
Yes | Yes | Yes | No |
Available cassettes** | Small tubing–plastic, Small tubing–metal, Standard tubing–plastic |
N/A | Standard tubing-plastic | Standard tubing-plastic |
Dispensing Technology |
Peristaltic Pump | Pressurized Valve System | Non-contact digital dispensing | Non-contact digital dispensing
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PC software included with the purchase |
Yes | Yes | Yes | Yes |
*E.g., alpha screen beads, polystyrene beads, yttrium oxide beads, tetra ethylene glycol carboxylated beads (0.8 µm)
Multidrop Combi Cassettes
Download specs |
Download specs | |
![]() Multidrop 384 Cassettes ONLY |
![]() Multidrop DW Cassettes ONLY |
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On-board interactive color touch screen |
No | No |
User Interface | 5-395 µl | 20-995 µl |
Plate formats |
standard 96-, 384-well plates; including low profile 384 plates | 96 standard and DW plates |
Plate height adjustment |
Fixed to 96- and 384-well plates | Fixed to standard 96- and 96 DW plates |
Cell dispensing |
Yes | Yes |
Bead* dispensing |
Yes | Yes |
Plate filling format |
Rows, columns | Rows, columns |
Automation/robot compatible |
Yes | No |
Available cassettes** |
Standard tubing–plastic | Standard tubing-plastic |
Dispensing Technology |
Peristaltic Pump |
Peristaltic Pump |
FiLLIt software included with purchase |
N/A | N/A |
*E.g., alpha screen beads, polystyrene beads, yttrium oxide beads, tetra ethylene glycol carboxylated beads (0.8 µm)
**Refer to Cassette Selection Guide for all available part numbers and configurations.
Software Solutions - Easy to use with ready to use protocols
Pico Software
An easy-to-use Multidrop PicoIT software platform with application-focused wizards and a highlighted loading guide allows effortless and quick plate set-up and operation. Available in 1-well and 8-well formats to support different throughputs and number of reagents and samples.
FILLit software
Multidrop Combi and Multidrop Combi nL reagent dispensers come with dedicated Thermo Scientific FILLit PC software, which allows users to develop protocols that can be run directly from the PC or transferred into instrument memory.
The FiLLIt Software is included free with the purchase of a MD Combi, MD Combi SMART2, or MD Combi nL.
Speed Testing Processes and Improve Reproducibility
Whether you work in a QC lab, or just want to increase the number of samples you can prepare in less time than with a pipette, Multidrop dispensers offer a convenient solution. Watch all four videos in the series to learn how Multidrop dispensers can help you.
Featured videos
Convenient, handy and ergonomic plate filling with the Thermo Scientific Multidrop dispensers
- Accommodates microplates from 6 to 1536 wells and plate heights of 5 to 50mm
- Precise dispensing over a 0.5 to 2500μL range
- Full robotic compatibility gives increased throughput
Multidrop Combi nL provides accurate, reliable low volume dispensing in the range of 50nL to 50µL
- Dispenses volumes of 50nL -50μL into 96-, 384- and 1536-well
- Fast dispensing and full robotic compatibility gives increased throughput
- Program to fill specific rows, columns or even individual wells for increased flexibility