Neurobiology ELISA Kits

Neurobiology ELISA kits are high-quality ELISA kits, designed for researchers studying neurological disorders or doing neuroscience-related research. These “neuroELISA” kits are designed to deliver accurate, sensitive, and fast Aβ (β-amyloid or amyloid beta), tau, and α-synuclein protein quantitation in sample types such as cerebrospinal fluid (CSF), cell culture supernatants, primary neurons, and brain tissue samples.

Popular neurobiology ELISA kit products

Human Amyloid beta 40 ELISA Kit
Human Amyloid beta 42 ELISA Kit
Human alpha-Synuclein ELISA Kit

Advantages of neuroELISA (neuro-ELISA) kits include:

  • Confidence in results–consistent, accurate, and sensitive measurements
  • Rigorous quality control–kits must meet quality-controlled specifications for sensitivity, dynamic range, precision, specificity, recovery, and lot-to-lot consistency
  • Ease of use–kits include pre-coated plates, capture/detection antibodies, standards, buffers and accessory reagents

Other popular neurobiology ELISA kits

Visit “Find ELISA kits by target” to search and select from all available neuroELISA kits

NeuroELISA kits to study proteins implicated in neurodegenerative disorders

ELISA enables specific, quantitative measurements of protein from a variety of biological sources including serum, plasma, and CSF (cerebrospinal fluid) from a variety of species. We offer ELISA kits for study of several proteins implicated in neurodegenerative disorders, such as:

  • Amyloid-beta (Aβ, beta amyloid or Abeta), which is crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer’s patients
  • Tau, a protein which stabilizes microtubules and which, when not functioning properly, is implicated in pathologies and dementias of the nervous system
  • Alpha synuclein (α-synuclein) which is thought to play an important role in maintaining a supply of synaptic vesicles in presynaptic terminals, and may  also help regulate the release of dopamine
PB4341_NeuroELISA_figure1

Figure 1. Typical 7-point standard curve for the Human Tau (Total) ELISA Kit (Cat. No. KHB0041). The dynamic range is 31–2,000 pg/mL, with an analytical sensitivity of <12 pg/mL.

PB4341_NeuroELISA_figure2

Figure 2. Recombinant Hu tau protein standard. Natural human (Hu) tau was serially diluted in Standard Diluent Buffer. The optical density of each dilution was plotted against the standard curve. Parallelism between the natural and recombinant protein indicates that the standard accurately reflects natural Hu tau content in samples.

Table 1. Linearity.

Human cerebrospinal fluid containing ™-amyloid 1-42 was serially diluted in Standard Diluent Buffer over the range of the assay. RPMI containing 10% fetal bovine serum was spiked with natural ™-amyloid 1-42 from APPtransfected cells and serially diluted in Standard Diluent Buffer over the range of the assay. Linear regression analysis of samples versus the expected concentration yielded a correlation coefficient of 0.99. (Occasional measurements >100% of expected are within the range of experimental values.)

Cerebrospinal fluid
Dilution Measured (pg/mL) Expected (pg/mL) Expected (%)
1/4 341.0 341.0  
1/8 185.4 170.5 108
1/16 94.6 85.3 107
1/32 41.2 42.6 97
Cell culture supernatant
Dilution Measured (pg/mL) Expected (pg/mL) Expected (%)
1/2 152.1 152.1  
1/4 76.4 76.0 101
1/8 38.4 38.0 101
1/16 15.2 19.0 80
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