A wide range of products—flexibility for your research
A wide range of surface-activated Dynabeads magnetic beads is available for covalent coupling of ligands to the bead surface. One can choose beads of different sizes, with a hydrophobic or hydrophilic surface, and with a variety of surface chemistries. For optimal results, select the right bead based on ligand type (Table 1). Note that in most applications several Dynabeads products can be used. Depending on the magnetic bead type, the ligand can be directly linked to the bead surface or indirectly linked through a reactive intermediate. Protocols can take place in a single tube, with just a few handling steps.
Table 1. Choose the right surface-activated Dynabeads for your application.
|Dynabeads Amine||Dynabeads Epoxy|
|Antibody||Low MW antigen1 or peptide|
|Protein or antibody|
|Antibody Fragment||Phage1 or antibody|
|Protein||Phage or carbohydrate|
|Peptide||Phage1 or antibody|
|Low MV antigen||Antibody|
|Nucleic acids, oligonucleotide, aptamer, PNA||Nucleic acid binding proteins1||4|
|DNA1, RNA1 or PCR amplicons1||4|
|Enzyme||Substrate or target for enzyme degradation|
|Organic chemistry derivatization, including introduction of new functional groups|
Best product choice for listed ligand and target.
Alternative choice for listed ligand and target.
Can be used for listed ligand and target.
1 Dynabeads pre-coupled with streptavidin may be the best product choice.
2 Dynabeads M-450 Epoxy.
3 Dynabeads M-450 Epoxy are recommended for isolation, stimulation, and expansion of cells.
4 Bifunctional crosslinkers may be introduced to immobilize oligonucleotides onto the surface of Dynabeads Amine.
Surface-activated Dynabeads product list
For Research Use Only. Not for use in diagnostic procedures.