Thermo Scientific™ Pierce™ Calibration Solutions for mass spectrometry are ready-to-use liquid formulations that can quickly calibrate Thermo Scientific™ LC-MS instrumentation. These mixtures are composed of highly purified, ionizable molecules or polymers specifically designed for positive or negative calibration of Thermo Scientific™ ion trap, orbitrap and triple quadrupole instruments. The calibration solutions are manufactured at an ISO 9001 facility and each lot is quality controlled with strict specifications. The stable solutions are provided in a leak-proof, high-purity PTFE bottle.

  • Strong peaks—mixture of instrument-optimized components in a mass spec compatible solvent  solution
  • Ready to use—load calibration solution into a syringe and inject into the instrument
  • High-purity—mass spectrometry-grade reagents in a non-leachable container
  • Stable—store at room temperature or refrigerator for more than one year
  • Validated—all calibration solutions have been fully tested using Thermo Scientific™ Mass Spectrometers

Choose the right calibration solution for your application

  Pierce™ LTQ ESI Positive Ion Calibration Solution Pierce™ LTQ Velos ESI Positive Ion Calibration Solution Pierce™ ESI Negative Ion Calibration Solution Pierce™ Triple Quadrapole Calibration Solution Pierce™ Triple Quadrapole Calibration Solution, Extended Mass Range
Recommended for Thermo Scientific™ mass spec instrument series LTQ, LTQ Orbitrap, LXQ, LCQ FLEET, Exactive LTQ Velos/Velos Pro, LTQ Orbitrap Velos/Orbitrap Velos Pro, Orbitrap Elite,
Q Exactive, Orbitrap Fusion Tribrid
LTQ, LTQ Velos, LTQ Orbitrap, Exactive TSQ Quantum, TSQ Discovery, TSQ Quantum Access,TSQ Vantage, TSQ Endura, TSQ Quantiva TSQ Quantum, TSQ Discovery, TSQ Quantum Access,TSQ Vantage, TSQ Endura, TSQ Quantiva
Components Caffeine, MRFA, Ultramark 1621 Caffeine, MRFA, Ultramark 1621, n-Butyl-amine SDS, sodium taurocholate,
Ultramark 1621
Tyrosine1, Tyrosine3, Tyrosine6 17 components†
Mass range 195-1522 74-1522 265-1680 182-997 69-2722 (Pos)
69-2934 (Neg)
Calibration mode Positive Positive Negative Positive Positive and Negative
Storage Room temp Room temp Room temp 2° to 8°C 2° to 8° C
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† See product page for details

Looking for a calibration solution to assess or calibrate column chromatography?

Thermo Scientific™ Pierce™ Peptide Retention Time Calibration Mixture contains a mixture of 14 heavy yeast peptides (hydrophobicity range 7.56-46.66) and is ideal for optimizing and assessing LC parameters,  identifying the total peptide elution window, and optimizing MS parameters.

Featured data

Thermo Scientific Pierce ESI Negative Calibration Solution spectra. Formulation: sodium dodecyl sulfate (2.9 μg/mL), sodium taurocholate (5.4 μg/mL) and Ultramark 1621 (0.001%) in an aqueous solution of acetonitrile (50%), methanol (25%) and acetic acid (1%).

Chromatographic analysis of the Thermo Scientific Pierce Peptide Retention Time Calibration Mixture. The Pierce™ Retention Time Calibration Mixture was also analyzed on a Thermo Scientific™ TSQ Vantage™ Mass Spectrometer using a Thermo Scientific™ Hypersil™ GOLD C18 column (1.0 x 150 mm) with a 1.0% per minute gradient at 120 μL per minute.