The most commonly used solvents or solvent blends include LC-MS grade water and acetonitrile, with ion pairing agents such as trifluoroacetic acid (TFA), formic acid (FA) or heptafluorobuteric acid (HFBA). These solvents are available as single component formulations or convenient blends. Solvents are manufactured in an ISO9001 facility and are provided with a Certificate of Analysis. Solvents and blends have been validated using Thermo Scientific™ Mass Spectrometers.

  • High purity—processed, filtered and sealed to help extend LC-MS column life
  • More choices—solvents and solvent blends to meet a variety of applications/needs
  • Stable—store for more than one year at room temperature
  • Validated—products evaluated with over 20 specifications measured and fully tested using Thermo Scientific Mass™ Spectrometers

Choose the right LC-MS solvent for your application

 Trifluoroacetic Acid (TFA)Formic Acid (FA)0.1% TFA in Acetonitrile, LC-MS Grade0.1%TFA in Water, LC-MS Grade0.1% FA in Acetonitrile, LC-MS Grade0.1% FA in Water, LC-MS Grade
StructureChemical structure of trifluoroacetic acid (TFA)Chemical structure of formic acid (FA)Chemical structure of trifluoroacetic acid (TFA)Chemical structure of trifluoroacetic acid (TFA)Chemical structure of formic acid (FA)Chemical structure of formic acid (FA)
FormulationSolventSolventSolvent BlendSolvent BlendSolvent BlendSolvent Blend
FormatsLiquid (in ampules or bottles)

Liquid (in ampules or bottles)

Liquid (bottles)Liquid (bottles)Liquid (bottles)Liquid (bottles)
Specifications measured>107-20>20>20>20>20
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Featured data

Specifications of Thermo Scientific Pierce 0.1% Trifluoroacetic Acid (v/v) in Acetonitrile.

Specifications of Thermo Scientific Pierce 0.1% Trifluoroacetic Acid (v/v) in Acetonitrile.

Related mass spec solvents and reagents

For Research Use Only. Not for use in diagnostic procedures.